New Pathophysiological Insights from Serum Proteome Profiling in Equine Atypical Myopathy

Autor: Caroline-J. Kruse, Marc Dieu, Benoît Renaud, Anne-Christine François, David Stern, Catherine Demazy, Sophie Burteau, François Boemer, Tatiana Art, Patricia Renard, Dominique-M. Votion

Publikováno v: ACS Omega, Vol 9, Iss 6, Pp 6505-6526 (2024)

Externí odkaz: https://doaj.org/article/e347f13f3c1c4c108aac0c7ea6dc020b

Tissue Specific Distribution and Activation of Sapindaceae Toxins in Horses Suffering from Atypical Myopathy

Autor: Johannes Sander, Michael Terhardt, Nils Janzen, Benoît Renaud, Caroline-Julia Kruse, Anne-Christine François, Clovis P. Wouters, François Boemer, Dominique-Marie Votion

Publikováno v: Animals, Vol 13, Iss 15, p 2410 (2023)

Equine atypical myopathy is caused by hypoglycin A (HGA) and methylenecyclopropylglycine (MCPrG), the known protoxins of sycamore maple (Acer pseudoplatanus). Various tissues from five atypical myopathy cases were analyzed but only HGA was found. Whe

Externí odkaz: https://doaj.org/article/857c4888d3f3431c8190123f28b23af2

Acer pseudoplatanus: A Potential Risk of Poisoning for Several Herbivore Species

Autor: Benoît Renaud, Caroline-Julia Kruse, Anne-Christine François, Lisa Grund, Carolin Bunert, Lucie Brisson, François Boemer, Gilbert Gault, Barbara Ghislain, Thierry Petitjean, Pascal Gustin, Dominique-Marie Votion

Publikováno v: Toxins, Vol 14, Iss 8, p 512 (2022)

Acer pseudoplatanus is a worldwide-distributed tree which contains toxins, among them hypoglycin A (HGA). This toxin is known to be responsible for poisoning in various species, including humans, equids, Père David’s deer and two-humped camels. We

Externí odkaz: https://doaj.org/article/be42c8a5accc4eaf93874ed18375f7fa

Answers to the Frequently Asked Questions Regarding Horse Feeding and Management Practices to Reduce the Risk of Atypical Myopathy

Autor: Dominique-Marie Votion, Anne-Christine François, Caroline Kruse, Benoit Renaud, Arnaud Farinelle, Marie-Catherine Bouquieaux, Christel Marcillaud-Pitel, Pascal Gustin

Publikováno v: Animals, Vol 10, Iss 2, p 365 (2020)

In 2014, atypical myopathy (AM) was linked to Acer pseudoplatanus (sycamore maple) in Europe. The emergence of this seasonal intoxication caused by a native tree has raised many questions. This manuscript aims at answering the five most frequently as

Externí odkaz: https://doaj.org/article/820514d06e9f4f35a45d76ed9bc0ba80

Metabolomic Signatures Discriminate Horses with Clinical Signs of Atypical Myopathy from Healthy Co-grazing Horses

Autor: François Boemer, Marie-Pierre Toquet, Eric Richard, Clovis Wouters, Anne-Christine François, Christel Marcillaud-Pitel, Justine Fortier-Guillaume, Pascal De Tullio, Benoît Renaud, D. Votion

Publikováno v: Journal of Proteome Research
Journal of Proteome Research, American Chemical Society, 2021, 20 (10), pp.4681-4692. ⟨10.1021/acs.jproteome.1c00225⟩

International audience; Atypical myopathy (AM) is a severe rhabdomyolysis syndrome that occurs in grazing horses. Despite the presence of toxins in their blood, all horses from the same pasture are not prone to display clinical signs of AM. The objec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dde2658a8502b8a43e0ac7c6aa93ab03
https://hal-normandie-univ.archives-ouvertes.fr/hal-03336827