Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Anne-Catherine Passaquin"'
Publikováno v:
Acta Physiologica Scandinavica. 176:283-292
The modulation of glucose uptake by cytosolic calcium and the role of insulin on calcium homeostasis in insulin-target cells are incompletely understood and results are contradictory. To address this issue, we used the C2C12 murine skeletal muscle ce
Autor:
Mathilde Renard, Urs T. Ruegg, Laurence Kay, Anne-Catherine Passaquin, Corinne Challet, Armand Mokhtarian, Theo Wallimann
Publikováno v:
Neuromuscular Disorders. 12:174-182
The mdx mouse serves as animal model for Duchenne muscular dystrophy. Energy status in muscles of mdx mice is impaired and we have demonstrated recently that the energy precursor creatine exerts beneficial effects on mdx skeletal muscle cells in cult
Publikováno v:
British Journal of Pharmacology. 124:1751-1759
Glucocorticoids, namely alpha-methylprednisolone (PDN) and deflazacort, are the only drugs reported to have a beneficial effect on the degenerative course of Duchenne muscular dystrophy (DMD). Increased cytosolic calcium concentrations ([Ca2+]c) have
Publikováno v:
British Journal of Pharmacology. 121:248-252
The use of the immunosuppressive drug cyclosporin A (CsA) is limited by two major side effects, nephrotoxicity and hypertension, which are caused by drug-induced local vasoconstriction. We have recently shown that CsA potentiates the contraction of i
Regulation of cytosolic calcium in skeletal muscle cells of the mdx mouse under conditions of stress
Publikováno v:
Scopus-Elsevier
1. In Duchenne muscular dystrophy (DMD) dysregulation of cytosolic calcium appears to be involved in the degeneration of skeletal muscle fibres. Therefore, we have studied the regulation of the free cytosolic calcium concentration ([Ca2+]c) under spe
Autor:
Laurent Metzinger, Urs T. Ruegg, Wim J. Leijendekker, Anne-Catherine Passaquin, Philippe Poindron
Publikováno v:
British Journal of Pharmacology. 116:2811-2816
1. Increased calcium (Ca2+) influx has been incriminated as a potential pathological mechanism in the chronic skeletal muscle degeneration exhibited by Duchenne muscular dystrophy (DMD) patients. We have studied the influence of the glucocorticoid al
Publikováno v:
Neuroscience Letters. 186:177-180
We have examined the incidence of new oxidant compounds, so-called lazaroids, on the morphological and biochemical aspects of differentiation of C2 mouse skeletal muscle cells. We show that three lazaroids (U-74006F, U-74389F and U-83836E) enhance fu
Publikováno v:
International Journal of Developmental Neuroscience. 12:363-372
We have investigated the effects of cell passaging and time in culture on astrocyte morphology, transferrin expression and the expression of two main astrocyte markers, glial fibrillary acidic protein (GFAP) and glutamine synthetase (GS: EC 6.3.1.2).
Publikováno v:
Journal of Neuroscience Research. 35:363-372
The differentiation of skeletal muscle cells from mdx mice which lack dystrophin expression was examined after glucocorticoid treatment, namely α-methylprednisolone (PDN). Primary skeletal muscle cell cultures were established from newborn mdx, cong
α-Methylprednisolone promotes skeletal myogenesis in dystrophin-deficient and control mouse cultures
Publikováno v:
Neuroscience Letters. 155:171-174
We have examined the influence of the glucocorticoid α-methylprednisolone (PDN) on the morphological differentiation of skeletal muscle cells derived from dystrophin-deficient C57BL/10 mdx , congenic C57BL/10 and allogenic Balb/c newborn mice. We sh