Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Anne-Catherine Dolens"'
Autor:
Siebe Loontiens, Anne-Catherine Dolens, Steven Strubbe, Inge Van de Walle, Finola E. Moore, Lisa Depestel, Suzanne Vanhauwaert, Filip Matthijssens, David M. Langenau, Frank Speleman, Pieter Van Vlierberghe, Kaat Durinck, Tom Taghon
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Transcriptional control of hematopoiesis involves complex regulatory networks and functional perturbations in one of these components often results in malignancies. Loss-of-function mutations in PHF6, encoding a presumed epigenetic regulator, have be
Externí odkaz:
https://doaj.org/article/5648833cfe364bd6bb29257e785baafe
Autor:
Inge Van de Walle, Anne-Catherine Dolens, Kaat Durinck, Katrien De Mulder, Wouter Van Loocke, Sagar Damle, Els Waegemans, Jelle De Medts, Imke Velghe, Magda De Smedt, Bart Vandekerckhove, Tessa Kerre, Jean Plum, Georges Leclercq, Ellen V. Rothenberg, Pieter Van Vlierberghe, Frank Speleman, Tom Taghon
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Strong Notch signalling promotes initial T cell lineage specification of lymphoid progenitors but is also permissive for thymic natural killer (NK) cell development. Here the authors show that GATA3 directs human T-lineage commitment by modulating No
Externí odkaz:
https://doaj.org/article/69f154ad67fa47219da5b76adf207d5e
Autor:
Nina Lambrechts, Kai Ling Liang, Imke Velghe, Steven Strubbe, Anne-Catherine Dolens, Tom Taghon
Publikováno v:
T-Cell Development ISBN: 9781071627396
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::038d680cb3f332910b255762c2375bca
https://doi.org/10.1007/978-1-0716-2740-2_21
https://doi.org/10.1007/978-1-0716-2740-2_21
Autor:
Nina, Lambrechts, Kai Ling, Liang, Imke, Velghe, Steven, Strubbe, Anne-Catherine, Dolens, Tom, Taghon
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2580
Not only is human T cell development characterized by unique changes in surface marker expression, but it also requires specific growth factors and conditions to mimic and study T cell development in vitro. In this chapter, we provide an overview of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d1bd075e0da0ce2df3e5cc7fab482b81
https://pubmed.ncbi.nlm.nih.gov/36374468
https://pubmed.ncbi.nlm.nih.gov/36374468
Autor:
Pieter-Jan Volders, Marieke Lavaert, Kaat Durinck, Anne-Catherine Dolens, Bart Vandekerckhove, Pieter Van Vlierberghe, Tessa Kerre, Karin Weening, Pieter Mestdagh, Juliette Roels, Franki Speleman, Joni Van der Meulen, Jo Vandesompele, Katleen De Preter, Imke Velghe, Jelle De Medts, Tom Taghon, Katrien De Mulder, Georges Leclercq
Publikováno v:
EMBO Rep
γδ and αβ T cells have unique roles in immunity and both originate in the thymus from T‐lineage committed precursors through distinct but unclear mechanisms. Here, we show that Notch1 activation is more stringently required for human γδ devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baedfbe25616434c5f7c4ed256549ede
https://doi.org/10.15252/embr.201949006
https://doi.org/10.15252/embr.201949006
Autor:
Kaat Durinck, Bart Vandekerckhove, Jelle De Medts, Ellen V. Rothenberg, Els Waegemans, Anne-Catherine Dolens, Frank Speleman, Tom Taghon, Pieter Van Vlierberghe, Georges Leclercq, Inge Van de Walle, Wouter Van Loocke, Magda De Smedt, Tessa Kerre, Sagar S. Damle, Imke Velghe, Katrien De Mulder, Jean Plum
Publikováno v:
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
NATURE COMMUNICATIONS
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
NATURE COMMUNICATIONS
The gradual reprogramming of haematopoietic precursors into the T-cell fate is characterized by at least two sequential developmental stages. Following Notch1-dependent T-cell lineage specification during which the first T-cell lineage genes are expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e33d29bec94b33dcf4cde80dad85cdd
https://doi.org/10.1038/ncomms11171
https://doi.org/10.1038/ncomms11171
Publikováno v:
T-Cell Development ISBN: 9781493928088
Not only is human T cell development characterized by unique changes in surface marker expression, but it also requires specific growth factors and conditions to mimic and study T cell development in vitro. In this chapter, we provide an overview of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a66d331bd593742f9d2d591ffe89dbba
https://doi.org/10.1007/978-1-4939-2809-5_20
https://doi.org/10.1007/978-1-4939-2809-5_20
Autor:
Tessa Kerre, Stijn Vanhee, Tom Taghon, Bart Vandekerckhove, Sarah Bonte, Anne-Catherine Dolens, Sylvia Snauwaert
Publikováno v:
T-Cell Development ISBN: 9781493928088
While in vitro models exist to study human T cell development, they still lack the precise environmental stimuli, such as the exact combination and levels of cytokines and chemokines, that are present in vivo. Moreover, studying the homing of hematop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59b3c0a8be0c3d0f7e3b363fe2f4683e
https://doi.org/10.1007/978-1-4939-2809-5_21
https://doi.org/10.1007/978-1-4939-2809-5_21
Autor:
Tom Taghon, Anne-Catherine Dolens
Publikováno v:
Nature Methods. 14:477-478
Two complementary approaches for directing human hematopoietic stem cells along the T cell lineage will have applications in both fundamental and translational research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56c2bd1307c880969eb06afd049d6ca9
https://doi.org/10.1038/nmeth.4277
https://doi.org/10.1038/nmeth.4277
Autor:
Sarah, Bonte, Sylvia, Snauwaert, Stijn, Vanhee, Anne-Catherine, Dolens, Tom, Taghon, Bart, Vandekerckhove, Tessa, Kerre
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1323
While in vitro models exist to study human T cell development, they still lack the precise environmental stimuli, such as the exact combination and levels of cytokines and chemokines, that are present in vivo. Moreover, studying the homing of hematop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b079e72ea012691d28f4ed6c7f373484
https://pubmed.ncbi.nlm.nih.gov/26294414
https://pubmed.ncbi.nlm.nih.gov/26294414