Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Anne de Cian"'
Autor:
Juliette Pulman, Catherine Botto, Hugo Malki, Duohao Ren, Paul Oudin, Anne De Cian, Marie As, Charlotte Izabelle, Bruno Saubamea, Valerie Forster, Stéphane Fouquet, Camille Robert, Céline Portal, Aziz El-Amraoui, Sylvain Fisson, Jean-Paul Concordet, Deniz Dalkara
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 4, Pp 102349- (2024)
Genome editing by CRISPR-Cas holds promise for the treatment of retinal dystrophies. For therapeutic gene editing, transient delivery of CRISPR-Cas9 is preferable to viral delivery which leads to long-term expression with potential adverse consequenc
Externí odkaz:
https://doaj.org/article/79b809bb916648639568bb98681ed82b
Autor:
Marwan Anoud, Emmanuelle Delagoutte, Quentin Helleu, Alice Brion, Evelyne Duvernois-Berthet, Marie As, Xavier Marques, Khadija Lamribet, Catherine Senamaud-Beaufort, Laurent Jourdren, Annie Adrait, Sophie Heinrich, Geraldine Toutirais, Sahima Hamlaoui, Giacomo Gropplero, Ilaria Giovannini, Loic Ponger, Marc Geze, Corinne Blugeon, Yohann Couté, Roberto Guidetti, Lorena Rebecchi, Carine Giovannangeli, Anne De Cian, Jean-Paul Concordet
Publikováno v:
eLife, Vol 13 (2024)
Tardigrades are microscopic animals renowned for their ability to withstand extreme conditions, including high doses of ionizing radiation (IR). To better understand their radio-resistance, we first characterized induction and repair of DNA double- a
Externí odkaz:
https://doaj.org/article/8cf2c13161a04e928c2749c468eb9c25
Autor:
Loélia Babin, Alice Darchen, Elie Robert, Zakia Aid, Rosalie Borry, Claire Soudais, Marion Piganeau, Anne De Cian, Carine Giovannangeli, Olivia Bawa, Charlotte Rigaud, Jean-Yves Scoazec, Lucile Couronné, Layla Veleanu, Agata Cieslak, Vahid Asnafi, David Sibon, Laurence Lamant, Fabienne Meggetto, Thomas Mercher, Erika Brunet
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-18 (2022)
Abstract Background Anaplastic large cell lymphoma positive for ALK (ALK+ ALCL) is a rare type of non-Hodgkin lymphoma. This lymphoma is caused by chromosomal translocations involving the anaplastic lymphoma kinase gene (ALK). In this study, we aimed
Externí odkaz:
https://doaj.org/article/a1c4dd48d3b24f998de122fdb6715403
Autor:
Lucie Bastin-Héline, Arthur de Fouchier, Song Cao, Fotini Koutroumpa, Gabriela Caballero-Vidal, Stefania Robakiewicz, Christelle Monsempes, Marie-Christine François, Tatiana Ribeyre, Annick Maria, Thomas Chertemps, Anne de Cian, William B Walker III, Guirong Wang, Emmanuelle Jacquin-Joly, Nicolas Montagné
Publikováno v:
eLife, Vol 8 (2019)
Sex pheromone receptors (PRs) are key players in chemical communication between mating partners in insects. In the highly diversified insect order Lepidoptera, male PRs tuned to female-emitted type I pheromones (which make up the vast majority of phe
Externí odkaz:
https://doaj.org/article/30faf62411314257b1b8412454834c8b
Autor:
Edwige B Garcin, Stéphanie Gon, Meghan R Sullivan, Gregory J Brunette, Anne De Cian, Jean-Paul Concordet, Carine Giovannangeli, Wilhelm G Dirks, Sonja Eberth, Kara A Bernstein, Rohit Prakash, Maria Jasin, Mauro Modesti
Publikováno v:
PLoS Genetics, Vol 15, Iss 10, p e1008355 (2019)
Deficiency in several of the classical human RAD51 paralogs [RAD51B, RAD51C, RAD51D, XRCC2 and XRCC3] is associated with cancer predisposition and Fanconi anemia. To investigate their functions, isogenic disruption mutants for each were generated in
Externí odkaz:
https://doaj.org/article/edf562de560749c6ba7db2b329674714
Autor:
Jean-Baptiste Renaud, Charlotte Boix, Marine Charpentier, Anne De Cian, Julien Cochennec, Evelyne Duvernois-Berthet, Loïc Perrouault, Laurent Tesson, Joanne Edouard, Reynald Thinard, Yacine Cherifi, Séverine Menoret, Sandra Fontanière, Noémie de Crozé, Alexandre Fraichard, Frédéric Sohm, Ignacio Anegon, Jean-Paul Concordet, Carine Giovannangeli
Publikováno v:
Cell Reports, Vol 14, Iss 9, Pp 2263-2272 (2016)
Genome editing has now been reported in many systems using TALEN and CRISPR-Cas9 nucleases. Precise mutations can be introduced during homology-directed repair with donor DNA carrying the wanted sequence edit, but efficiency is usually lower than for
Externí odkaz:
https://doaj.org/article/9e72daf905044cdabb15827d401b0355
Autor:
Patrick Torbey, Elodie Thierion, Samuel Collombet, Anne de Cian, Carole Desmarquet-Trin-Dinh, Mathilde Dura, Jean-Paul Concordet, Patrick Charnay, Pascale Gilardi-Hebenstreit
Publikováno v:
PLoS Genetics, Vol 14, Iss 8, p e1007581 (2018)
Cis-regulation plays an essential role in the control of gene expression, and is particularly complex and poorly understood for developmental genes, which are subject to multiple levels of modulation. In this study, we performed a global analysis of
Externí odkaz:
https://doaj.org/article/77074dbda8704094814e9fc95805e458
Autor:
Thibaut Larcher, Aude Lafoux, Laurent Tesson, Séverine Remy, Virginie Thepenier, Virginie François, Caroline Le Guiner, Helicia Goubin, Maéva Dutilleul, Lydie Guigand, Gilles Toumaniantz, Anne De Cian, Charlotte Boix, Jean-Baptiste Renaud, Yan Cherel, Carine Giovannangeli, Jean-Paul Concordet, Ignacio Anegon, Corinne Huchet
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110371 (2014)
A few animal models of Duchenne muscular dystrophy (DMD) are available, large ones such as pigs or dogs being expensive and difficult to handle. Mdx (X-linked muscular dystrophy) mice only partially mimic the human disease, with limited chronic muscu
Externí odkaz:
https://doaj.org/article/5360c456b3714a1faaa7b80cda6608fc
Autor:
Anne De Cian, Elise Praly, Fangyuan Ding, Vijender Singh, Christophe Lavelle, Eric Le Cam, Vincent Croquette, Olivier Piétrement, David Bensimon
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31845 (2012)
Among chromatin remodeling factors, the ISWI family displays a nucleosome-enhanced ATPase activity coupled to DNA translocation. While these enzymes are known to bind to DNA, their activity has not been fully characterized. Here we use TEM imaging an
Externí odkaz:
https://doaj.org/article/0d81eed5b47e47519dfde2a445936f3c
Autor:
Anne-Laure Gaillard, Teddy Mohamad, Feng B. Quan, Anne de Cian, Christian Mosiman, Hervé Tostivint, Guillaume Pézeron
Publikováno v:
Developmental Biology. 496:36-51
Urp1 and Urp2 are two neuropeptides, members of the Urotensin 2 family, that have been recently involved in the control of body axis morphogenesis in zebrafish. They are produced by a population of sensory spinal neurons, called cerebrospinal fluid c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c3f8a0413be8ca7f195f6f93c229b9a
https://doi.org/10.1016/j.ydbio.2023.01.010
https://doi.org/10.1016/j.ydbio.2023.01.010