Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Anne Zeck"'
Autor:
Teresa R. Wagner, Simone Blaess, Inga B. Leske, Desiree I. Frecot, Marius Gramlich, Bjoern Traenkle, Philipp D. Kaiser, Dominik Seyfried, Sandra Maier, Amélie Rezza, Fabiane Sônego, Kader Thiam, Stefania Pezzana, Anne Zeck, Cécile Gouttefangeas, Armin M. Scholz, Stefan Nueske, Andreas Maurer, Manfred Kneilling, Bernd J. Pichler, Dominik Sonanini, Ulrich Rothbauer
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Signal-regulatory protein α (SIRPα) expressed by myeloid cells is of particular interest for therapeutic strategies targeting the interaction between SIRPα and the “don’t eat me” ligand CD47 and as a marker to monitor macrophage infiltration
Externí odkaz:
https://doaj.org/article/29efe43cd84c4093b9130cdff8fcf447
Autor:
Matthias Becker, Monika Strengert, Daniel Junker, Philipp D. Kaiser, Tobias Kerrinnes, Bjoern Traenkle, Heiko Dinter, Julia Häring, Stéphane Ghozzi, Anne Zeck, Frank Weise, Andreas Peter, Sebastian Hörber, Simon Fink, Felix Ruoff, Alex Dulovic, Tamam Bakchoul, Armin Baillot, Stefan Lohse, Markus Cornberg, Thomas Illig, Jens Gottlieb, Sigrun Smola, André Karch, Klaus Berger, Hans-Georg Rammensee, Katja Schenke-Layland, Annika Nelde, Melanie Märklin, Jonas S. Heitmann, Juliane S. Walz, Markus Templin, Thomas O. Joos, Ulrich Rothbauer, Gérard Krause, Nicole Schneiderhan-Marra
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Serology is an important way to monitor SARS-CoV-2 infection in the population and support vaccine development. Here the authors develop a multiplex immunoassay including spike and nucleocapsid proteins of SARS-CoV-2 and the endemic human coronavirus
Externí odkaz:
https://doaj.org/article/873a2271e3d141e88ecbd175b0df6297
Autor:
Bjoern Traenkle, Philipp D. Kaiser, Stefania Pezzana, Jennifer Richardson, Marius Gramlich, Teresa R. Wagner, Dominik Seyfried, Melissa Weldle, Stefanie Holz, Yana Parfyonova, Stefan Nueske, Armin M. Scholz, Anne Zeck, Meike Jakobi, Nicole Schneiderhan-Marra, Martin Schaller, Andreas Maurer, Cécile Gouttefangeas, Manfred Kneilling, Bernd J. Pichler, Dominik Sonanini, Ulrich Rothbauer
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The advancement of new immunotherapies necessitates appropriate probes to monitor the presence and distribution of distinct immune cell populations. Considering the key role of CD4+ cells in regulating immunological processes, we generated novel sing
Externí odkaz:
https://doaj.org/article/843af024f10946eba486517b59dfb1c6
Autor:
Rui-Rui Guo, Gerard Comamala, Huan-Huan Yang, Marius Gramlich, Ya-Min Du, Ting Wang, Anne Zeck, Kasper Dyrberg Rand, Li Liu, Josef Voglmeir
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Peptide-N4-(N-acetyl-β-glucosaminyl) asparagine amidases (PNGases, N-glycanases, EC 3.5.1.52) are indispensable tools in releasing N-glycans from glycoproteins. So far, only a limited number of PNGase candidates are available for the structural anal
Externí odkaz:
https://doaj.org/article/65b1797d3ed742ffaccd2da19fde2d33
Autor:
Marius Gramlich, Henry C. W. Hays, Scott Crichton, Philipp D. Kaiser, Anne Heine, Nicole Schneiderhan-Marra, Ulrich Rothbauer, Dieter Stoll, Sandra Maier, Anne Zeck
Publikováno v:
Antibodies, Vol 10, Iss 1, p 11 (2021)
Annexin-A1 (ANXA1) belongs to a class of highly homologous Ca2+-dependent phospholipid-binding proteins. Its structure consists of a core region composed of four homologous repeats arranged in a compact, hydrolysis-resistant structure and an N-termin
Externí odkaz:
https://doaj.org/article/79e6141a86e64fa8b9714ae476fdbe1c
Autor:
Anne Zeck, Nicole Schneiderhan-Marra, Sandra Maier, Markus F. Templin, Meike Jakobi, Christopher Shipp, Claus Burkhardt, Luisa Pickarski, Nora Feuerer, Elsa Arefaine, Florian Billing, Simon Fink, Robin Kretz, Rumen Krastev, Hanna Hartmann, Bernadette Walter
Publikováno v:
ACS Applied Materials & Interfaces. 13:55534-55549
A full understanding of the relationship between surface properties, protein adsorption, and immune responses is lacking but is of great interest for the design of biomaterials with desired biological profiles. In this study, polyelectrolyte multilay
Autor:
Ulrich Rothbauer, Anne Zeck, Cornelia Sommersdorf, Markus F. Templin, Oliver Poetz, Sandra Maier, Thomas O. Joos, Ulrich Kratzer, Teresa R Wagner
Publikováno v:
Bioconjugate Chemistry. 32:1960-1965
N-Hydroxysuccinimide esters of small molecules are widely used to modify biomolecules such as antibodies or proteins. Primary amine groups preferably react with the ester to form covalent amide bonds. Currently, protocols strongly recommend replacing
Autor:
Marius Gramlich, Sandra Maier, Philipp D. Kaiser, Bjoern Traenkle, Teresa R. Wagner, Josef Voglmeir, Dieter Stoll, Ulrich Rothbauer, Anne Zeck
Publikováno v:
Analytical chemistry. 94(27)
N-linked glycosylation is a ubiquitous posttranslational modification of proteins. While it plays an important role in the biological function of proteins, it often poses a major challenge for their analytical characterization. Currently available pe
Autor:
Gérard Krause, Sebastian Hörber, Anne Zeck, Alex Dulovic, Philipp D. Kaiser, Tamam Bakchoul, Katja Schenke-Layland, Klaus Berger, Nicole Schneiderhan-Marra, Andreas Peter, Bjoern Traenkle, Armin Baillot, Frank Weise, Monika Strengert, Markus F. Templin, Annika Nelde, Tobias Kerrinnes, Thomas Illig, Melanie Märklin, Matthias Becker, Daniel Junker, Julia Häring, Heiko Dinter, Markus Cornberg, Jonas S. Heitmann, Stéphane Ghozzi, Hans-Georg Rammensee, Sigrun Smola, Jens Gottlieb, Simon Fink, Ulrich Rothbauer, Juliane S. Walz, Felix Ruoff, André Karch, Stefan Lohse, Thomas O. Joos
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nat. Commun. 12:1152 (2021)
Nature Communications
Nature communications
England
Nat. Commun. 12:1152 (2021)
Nature Communications
Nature communications
England
The humoral immune response to SARS-CoV-2 is a benchmark for immunity and detailed analysis is required to understand the manifestation and progression of COVID-19, monitor seroconversion within the general population, and support vaccine development
Autor:
Andreas Unsoeld, David Mentrup, Elke Prade, Anne Zeck, Ingo Gorr, Fabian Stiefel, Erik Arango Gutierrez
Publikováno v:
Biotechnology and Bioengineering
A high degree of charge heterogeneity is an unfavorable phenomenon commonly observed for therapeutic monoclonal antibodies (mAbs). Removal of these impurities during manufacturing often comes at the cost of impaired step yields. A wide spectrum of po