Supplementary Methods, Figure 1, Table 1 from A Phase I First-in-Human Study of Enoticumab (REGN421), a Fully Human Delta-like Ligand 4 (Dll4) Monoclonal Antibody in Patients with Advanced Solid Tumors

Autor: Antonio Jimeno, Adrian Harris, Russell Leek, Ana Kostic, Albert Thomas DiCioccio, Richard J. Kao, Liming Liu, Lieve Adriaens, Wells A. Messersmith, Anne Younger, Jennifer R. Diamond, Robert Matthew Strother, Patricia LoRusso, Elena Gabriela Chiorean

Supplementary Methods, Figure 1, Table 1. Supplementary Figure 1: Vascular expression of Dll4 versus CD31 in archive tumor tissue biopsies -Supplementary Table 1: Correlations between VEGFR-2 VQ and Notch1, Notch3, Dll4 Expression in Archive Samples

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b636fa0c01ede30739e416fd50d2d258
https://doi.org/10.1158/1078-0432.22461600

Innovation in work-integrated learning

Autor: Judie Kay, Leoni Russell, Judith Smith, Sonia Ferns, Anne Younger

Publikováno v: Advances in Research, Theory and Practice in Work-Integrated Learning ISBN: 9781003021049
Advances in Research, Theory and Practice in Work-Integrated Learning

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b6768d0a942babc492cbbb75b5eda5a1
https://doi.org/10.4324/9781003021049-16

What encourages and constrains parent participation on boards of trustees of low-decile primary schools?

Autor: Lexie Grudnoff, Anne Younger

Publikováno v: set: Research Information for Teachers. :16-22

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::07e40b15793f35357d10135dd2b9d0e0
https://doi.org/10.18296/set.0079

Phase I/IB multicenter study of afatinib in combination with capecitabine in patients (pts) with refractory solid tumors and pancreatico-biliary cancers

Autor: Mary W. Redman, Hannah H Lee, Kinsey A. McCormick, Safi Shahda, Colin C. Pritchard, Vijayakrishna K. Gadi, Bert H. O'Neil, Reina Hibbert, Stacey A. Cohen, Anne Younger, Andrew L. Coveler, William P. Harris, Amy E. Chang, E. Gabriela Chiorean

Publikováno v: Journal of Clinical Oncology. 35:TPS515-TPS515

TPS515 Background: The epidermal growth factor receptor (EGFR)/HER2 pathway is overactive in several solid tumors, including gastroesophageal, hepatic, colorectal, and pancreatico-biliary cancers. Afatinib is an irreversible inhibitor of the Erb fami

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ee22c3e0046586d82c8298ba2321def7
https://doi.org/10.1200/jco.2017.35.4_suppl.tps515

Phase I study of REGN421 (R)/SAR153192, a fully-human delta-like ligand 4 (Dll4) monoclonal antibody (mAb), in patients with advanced solid tumors

Autor: Lieve Adriaens, Robert Matthew Strother, Wells A. Messersmith, E. Gabriela Chiorean, Leah Plato, Anne Younger, Antonio Jimeno, A. Thomas DiCioccio, Liming Liu, Israel Lowy, Muaiad Kittaneh, Richard J. Kao, Patricia LoRusso, Jennifer R. Diamond, Doug Sawyer, Carrie Brownstein, Pamela Trail

Publikováno v: Journal of Clinical Oncology. 31:2502-2502

2502 Background: Dll4, a Notch receptor ligand, may have a role in tumor angiogenesis and is an emerging anticancer target. REGN421 (R) is a fully human IgG1mAb that binds human Dll4 and disrupts Notch-mediated signaling. Methods: Primary objectives

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a9790dda4352a2cbc58d7e49ef532d65
https://doi.org/10.1200/jco.2013.31.15_suppl.2502