Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Anne Wuttke"'
Autor:
Anne Wuttke
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 116:281-290
Pancreatic β-cells are clustered in islets of Langerhans and secrete insulin in response to increased concentrations of circulating glucose. Insulin in turn acts on liver, muscle and fat tissue to store energy and normalize the blood glucose level.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f69d2e630c4ff9dbafc9abd0ff904ab2
https://doi.org/10.1111/bcpt.12369
https://doi.org/10.1111/bcpt.12369
Publikováno v:
The FASEB Journal. 27:1610-1620
Diacylglycerol (DAG) controls numerous cell functions by regulating the localization of C1-domain-containing proteins, including protein kinase C (PKC), but little is known about the spatiotemporal dynamics of the lipid. Here, we explored plasma memb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db1b6af187ba9c8c2308e0cb07477854
https://doi.org/10.1096/fj.12-221499
https://doi.org/10.1096/fj.12-221499
Publikováno v:
The Journal of Biological Chemistry
PKC signaling has been implicated in the regulation of many cell functions, including metabolism, cell death, proliferation, and secretion. Activation of conventional and novel PKC isoforms is associated with their Ca2+- and/or diacylglycerol (DAG)-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44b6ac626dce0dbda5e7f64535867980
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-303385
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-303385
Autor:
Klaus-Peter Stahmann, Anne Wuttke, Susann Barig, Mahesh M. Huddar, Susanne Nieland, Romy Alisch, Yvonne Gräser, Klaus Schnitzlein
Publikováno v:
Engineering in Life Sciences. 11:387-394
A disadvantage of most microbial production processes is the need for sterile techniques. The objective of this study was the development of a robust fungal system allowing monoseptic growth with a minimum of sterile technique in plastic barrels. Sel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d43327d54bf725d0cbe95be30b3f941
https://doi.org/10.1002/elsc.201000219
https://doi.org/10.1002/elsc.201000219
Publikováno v:
Journal of Cell Science. 123:1492-1502
Phosphoinositides regulate numerous processes in various subcellular compartments. Whereas many stimuli trigger changes in the plasma-membrane PtdIns(4,5)P(2) concentration, little is known about its precursor, PtdIns(4)P, in particular whether there
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3bf280b2153776a97a33e22d80d03b3
https://doi.org/10.1242/jcs.060525
https://doi.org/10.1242/jcs.060525
Publikováno v:
Diabetes. 56:818-826
Phosphatidylinositol-4,5-bisphosphate (PIP(2)) is important for a variety of cellular processes as a precursor for second messengers and by regulating ion channels, the cytoskeleton, and vesicle traffic in many types of cells, including insulin-secre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ca4fcbb039f040114ceee1ddd05acf0
https://doi.org/10.2337/db06-0843
https://doi.org/10.2337/db06-0843
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 27(4)
Diacylglycerol (DAG) controls numerous cell functions by regulating the localization of C1-domain-containing proteins, including protein kinase C (PKC), but little is known about the spatiotemporal dynamics of the lipid. Here, we explored plasma memb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::107986f1461ee4ac92c69d3aa7fe2804
https://pubmed.ncbi.nlm.nih.gov/23299857
https://pubmed.ncbi.nlm.nih.gov/23299857
Autor:
Olof Idevall-Hagren, Tingting Li, Anders Tengholm, Philippe Ravassard, Rikard G. Fred, Abdullah Al-Amin, Dariush Mokhtari, Kyrill Turpaev, Jia Li, Anne Wuttke, Raphael Scharfmann, Nils Welsh
Publikováno v:
Diabetologia. 56(6)
AIMS/HYPOTHESIS: It is not clear how small tyrosine kinase inhibitors, such as imatinib mesilate, protect against diabetes and beta cell death. The aim of this study was to determine whether imatinib, as compared with the non-cAbl-inhibitor sunitinib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0070ac18d8f245bb6063abeb623e9a9
https://pubmed.ncbi.nlm.nih.gov/23462796
https://pubmed.ncbi.nlm.nih.gov/23462796
Publikováno v:
Cryobiology
Freeze-drying of bacterial cells with retained viability and activity after storage requires appropriate formulation, i.e. mixing of physiologically adapted cell populations with suitable protective agents, and control of the freeze-drying process. P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f0002f3c299373f138413db59b488f0
https://pubmed.ncbi.nlm.nih.gov/22266474
https://pubmed.ncbi.nlm.nih.gov/22266474
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 645
To improve our understanding of the important roles played by inositol lipid derivatives in signalling and other cellular processes, it is crucial to measure phosphoinositide concentration changes in individual cells with high spatial and temporal re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7724d5e15cdf504d4f4c76392894897e
https://pubmed.ncbi.nlm.nih.gov/20645191
https://pubmed.ncbi.nlm.nih.gov/20645191