Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Anne Wing-Mui Lee"'
Autor:
Lanqi Gong, Jie Luo, Yu Zhang, Yuma Yang, Shanshan Li, Xiaona Fang, Baifeng Zhang, Jiao Huang, Larry Ka-Yue Chow, Dittman Chung, Jinlin Huang, Cuicui Huang, Qin Liu, Lu Bai, Yuen Chak Tiu, Pingan Wu, Yan Wang, George Sai-Wah Tsao, Dora Lai-wan Kwong, Anne Wing-Mui Lee, Wei Dai, Xin-Yuan Guan
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-24 (2023)
Response rates to immunotherapies in patients with nasopharyngeal carcinoma (NPC) are still limited. Here the authors show that tumor-restricted CD70 correlates with regulatory T cell abundance and suppressive activity in NPC and that CD70 blockade i
Externí odkaz:
https://doaj.org/article/b6da0bb5eab74ad7aa459a56759ab2ba
Autor:
Lanqi Gong, Yu Zhang, Yuma Yang, Qian Yan, Jifeng Ren, Jie Luo, Yuen Chak Tiu, Xiaona Fang, Beilei Liu, Raymond Hiu Wai Lam, Ka‐On Lam, Anne Wing‐Mui Lee, Xin‐Yuan Guan
Publikováno v:
Hepatology Communications, Vol 6, Iss 11, Pp 3194-3211 (2022)
Abstract The tumor microenvironment (TME) is considered to be one of the vital mediators of tumor progression. Extracellular matrix (ECM), infiltrating immune cells, and stromal cells collectively constitute the complex ecosystem with varied biochemi
Externí odkaz:
https://doaj.org/article/2417c7107cde4ecc955f2f98a29b0b82
Autor:
Larry Ka-Yue Chow, Dittman Lai-Shun Chung, Lihua Tao, Kui Fat Chan, Stewart Yuk Tung, Roger Kai Cheong Ngan, Wai Tong Ng, Anne Wing-Mui Lee, Chun Chung Yau, Dora Lai-Wan Kwong, Victor Ho-Fun Lee, Ka-On Lam, Jiayan Liu, Honglin Chen, Wei Dai, Maria Li Lung
Publikováno v:
EBioMedicine, Vol 86, Iss , Pp 104357- (2022)
Summary: Background: Epstein-Barr virus (EBV) latent infection is associated with genome-wide epigenomic changes in several malignancies, but its role in epigenetic dysregulation remains unclear in nasopharyngeal carcinoma (NPC). Methods: To investig
Externí odkaz:
https://doaj.org/article/2bc6dad55c7b4c878e2ab635d488677a
Autor:
Kin-Sang Lau, Ben Man-Fei Cheung, Ka-On Lam, Sum-Yin Chan, Ka-Ming Lam, Chun-Fai Yeung, Ivan Fan-Ngai Hung, Dora Lai-Wan Kwong, Chi-Chung Tong, To-Wai Leung, Mai-Yee Luk, Anne Wing-Mui Lee, Kwok-Keung Yuen, Victor Ho-Fun Lee
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-5 (2021)
Abstract Background Tuberculosis (TB) reactivation has been increasingly identified following immune checkpoint inhibitor (ICI) therapy for cancer patients. However there has been no report on TB reactivation in the gastrointestinal tract. In the rep
Externí odkaz:
https://doaj.org/article/2540bea4e0744c0db3e2bb0711216fb7
Autor:
Lanqi Gong, Dora Lai-Wan Kwong, Wei Dai, Pingan Wu, Shanshan Li, Qian Yan, Yu Zhang, Baifeng Zhang, Xiaona Fang, Li Liu, Min Luo, Beilei Liu, Larry Ka-Yue Chow, Qingyun Chen, Jinlin Huang, Victor Ho-Fun Lee, Ka-On Lam, Anthony Wing-Ip Lo, Zhiwei Chen, Yan Wang, Anne Wing-Mui Lee, Xin-Yuan Guan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
The tumor microenvironment can influence patient survival response to therapy. Here, the authors used single-cell sequencing to investigate the microenvironment of nasopharyngeal cancer and identify tumor-specific signatures in five stromal clusters
Externí odkaz:
https://doaj.org/article/0b2c6fcf4f674aa2b645939100155c52
Autor:
Zhi-Ming MAI, Roger Kai-Cheong NGAN, Dora Lai-Wan KWONG, Wai-Tong NG, Kam-Tong Yuen, Dennis Kai-Ming Ip, Yap-Hang CHAN, Anne Wing-Mui LEE, Sai-Yin HO, Maria Li LUNG, Tai-Hing LAM
Publikováno v:
Nutrition Journal, Vol 20, Iss 1, Pp 1-10 (2021)
Abstract Background The role of dietary fiber intake on risk of nasopharyngeal carcinoma (NPC) remains unclear. We examined the associations of dietary fiber intake on the risk of NPC adjusting for a comprehensive list of potential confounders. Metho
Externí odkaz:
https://doaj.org/article/9d7f399651a34e27adccd4d327da2c01
Autor:
Lvwen Ning, Josephine Mun-Yee Ko, Valen Zhuoyou Yu, Hoi Yan Ng, Candy King-Chi Chan, Lihua Tao, Shiu-Yeung Lam, Merrin Man-Long Leong, Roger Kai-Cheong Ngan, Dora Lai-Wan Kwong, Anne Wing-Mui Lee, Wai-Tong Ng, Ashley Cheng, Stewart Tung, Victor Ho-Fun Lee, Ka-On Lam, Chung-Kong Kwan, Wing-Sum Li, Stephen Yau, Jin-Xin Bei, Maria Li Lung
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-13 (2020)
Here the authors report a major histocompatibility complex (MHC) association analysis for nasopharyngeal carcinoma in Chinese individuals from Hong Kong, finding 8 independent associated loci associated with lower risk for developing nasopharyngeal c
Externí odkaz:
https://doaj.org/article/f82cb968f4d947bb91dd4a6ed21c1e75
Autor:
Lanqi Gong, Dora Lai-Wan Kwong, Wei Dai, Pingan Wu, Yan Wang, Anne Wing-Mui Lee, Xin-Yuan Guan
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
The evolution of the tumor microenvironment (TME) is a cancer-dependent and dynamic process. The TME is often a complex ecosystem with immunosuppressive and tumor-promoting functions. Conventional chemotherapy and radiotherapy, primarily focus on ind
Externí odkaz:
https://doaj.org/article/f39dc4c770664c44ac4ec6fe5d1f35c6
Autor:
Lijun Wang, Zhi-Ming Mai, Roger Kai-Cheong Ngan, Wai-Tong Ng, Jia-Huang Lin, Dora Lai-Wan Kwong, Shing-Chun Chiang, Kam-Tong Yuen, Alice Wan-Ying Ng, Dennis Kai-Ming Ip, Yap-Hang Chan, Anne Wing-Mui Lee, Maria Li Lung, Sai Yin Ho, Tai-Hing Lam
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundCigarette smoking is associated with nasopharyngeal cancer (NPC) risk. Whether quitting reduces the risk is unclear. We investigated the associations of NPC with duration of and age at quitting in an endemic region.MethodsWe investigated th
Externí odkaz:
https://doaj.org/article/a8a72060e5ed4c35a521dd9c3b4c7893
Autor:
Sik-Kwan Chan BSc, Sze-Chun Chau BSc, Sum-Yin Chan FRCR, Chi-Chung Tong FRCR, Ka-On Lam FRCR, Dora Lai-Wan Kwong MD, To-Wai Leung MD, Mai-Yee Luk FRCR, Anne Wing-Mui Lee MD, Horace Cheuk-Wai Choi PhD, Victor Ho-Fun Lee MD
Publikováno v:
Cancer Control, Vol 28 (2021)
Background Nasopharyngeal carcinoma (NPC) is endemic in Hong Kong with a skewed geographical and ethnic distribution. We performed an epidemiological study of NPC in Cheung Chau Island, a fishing village with very minimal residential mobility, and co
Externí odkaz:
https://doaj.org/article/a73dbb25e36e46d2bc886a774cf77a25