Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Anne W. Wyke"'
Publikováno v:
European Journal of Biochemistry. 127:553-558
The cell-wall composition and degree of cross-linking of peptidoglycan in a strain of Staphylococcus aureus (strain MR-1) which is highly resistant to methicillin were similar to those of other strains of S. aureus. When the organism was grown in the
Autor:
Richard Jones, Valerie G. Brunton, Anne W. Wyke, Margaret C. Frame, David G.C. Owens, Egle Avizienyte
Publikováno v:
British Journal of Cancer
Elevated expression and/or activity of c-Src, the prototype of the Src family of protein tyrosine kinases, is associated with the development of human colon cancer. However, despite the known pleiotropic effects of these kinases in promoting (a) cell
Autor:
Anne W. Wyke, Valerie G. Brunton, Gordon W. McLean, Robert Jones, Margaret C. Frame, Egle Avizienyte, M. Andrew Westhoff
Publikováno v:
Nature cell biology. 4(8)
Although Src expression and activity are often elevated in colon cancer, the precise consequences of overexpression of the non-catalytic Src homology (SH) domains, or enhanced catalytic activity, are unknown. We show that, in KM12C colon cancer cells
Publikováno v:
Cellular signalling. 4(3)
When Rat-1 cells bearing the ts LA29 mutant of Rous sarcoma virus (Rat1 LA29) are shifted from restrictive to permissive temperature, the pp60v-Src tyrosine kinase is activated and there is an increase in the cellular level of sn1,2-diacylglycerol (D
Autor:
Anne W. Wyke, H. R. Perkins
Publikováno v:
Journal of General Microbiology. 88:159-168
SUMMARY: A soluble extract from Corynebacterium poinsettiae able to synthesize the nucleotide precursor of its peptidoglycan was prepared. This extract contained all the enzymes necessary for the synthesis of the peptide side-chain. The specificity o
Publikováno v:
FEMS Microbiology Letters. 10:119-122
Autor:
Anne W. Wyke
Publikováno v:
FEMS Microbiology Letters. 22:133-138
Five penicillin-binding proteins have been isolated from detergent-solubilized membranes of Staphylococcus aureus and have been separated from other membrane proteins by covalent affinity chromatography on 6-aminopenicillanic acid-Sepharose. The PBPs
Publikováno v:
Journal of Biological Chemistry. 247:2808-2813
Embryonic chick calvaria (cranial bones) were cultured in the presence of [35S]cysteine and labeled procollagen, a collagen precursor, was isolated. Incorporation of the 35S label in the pro-α1 chain of procollagen permitted its use as a relatively
Publikováno v:
Biochemical and Biophysical Research Communications. 48:892-897
In medium from cultured chick embryo fibroblasts a species of collagen molecule was found which contained chains that were like α 1 , but were larger and contained cysteine. Pepsin treatment or reduction of disulfide linkages was required for separa
Publikováno v:
European journal of biochemistry. 119(2)
The degree of cross-linking of the peotidoglycan of Staphylococcus aureus H and mutants lacking penicillin-binding proteins 1 and 4 was studies. No major changes were ovserved in organisms lacking protein 1 whereas oloss of protein 4 was accompanied