Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Anne Vehlow"'
Autor:
Mandy Schott, Anne Vehlow, Moritz Benka, Simon Lagies, Bernd Kammerer, Thorsten Rieckmann, Nils Cordes
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 179, Iss , Pp 117305- (2024)
Numerous natural substances have anti-cancer properties. Especially indigenous people use aqueous plant extracts for tea or ointments including Dioscorea sansibarensis Pax to treat various diseases. The aim of this study was to evaluate the cytotoxic
Externí odkaz:
https://doaj.org/article/4ca15d34ee5f47ccb2649950b218fa55
Publikováno v:
Cells, Vol 11, Iss 14, p 2133 (2022)
Glioblastoma is a devastating malignant disease with poor patient overall survival. Strong invasiveness and resistance to radiochemotherapy have challenged the identification of molecular targets that can finally improve treatment outcomes. This stud
Externí odkaz:
https://doaj.org/article/02d569570af7414ca8faad7976f17c9e
Autor:
Marcel Naumann, Arun Pal, Anand Goswami, Xenia Lojewski, Julia Japtok, Anne Vehlow, Maximilian Naujock, René Günther, Mengmeng Jin, Nancy Stanslowsky, Peter Reinhardt, Jared Sterneckert, Marie Frickenhaus, Francisco Pan-Montojo, Erik Storkebaum, Ina Poser, Axel Freischmidt, Jochen H. Weishaupt, Karlheinz Holzmann, Dirk Troost, Albert C. Ludolph, Tobias M. Boeckers, Stefan Liebau, Susanne Petri, Nils Cordes, Anthony A. Hyman, Florian Wegner, Stephan W. Grill, Joachim Weis, Alexander Storch, Andreas Hermann
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Abnormal cytoplasmic aggregates of FUS are a hallmark of some forms of amyotrophic lateral sclerosis (ALS). Here, using neurons derived from patients with FUS-ALS, the authors demonstrate that impairment of PARP-dependent DNA damage signaling is an e
Externí odkaz:
https://doaj.org/article/421d7fe19126448d9734fe819843c747
Autor:
Anne Vehlow, Erik Klapproth, Sha Jin, Ricarda Hannen, Maria Hauswald, Jörg-Walter Bartsch, Christopher Nimsky, Achim Temme, Birgit Leitinger, Nils Cordes
Publikováno v:
Cell Reports, Vol 26, Iss 13, Pp 3672-3683.e7 (2019)
Summary: Glioblastoma (GBM) is highly refractory to therapy and associated with poor clinical outcome. Here, we reveal a critical function of the promitotic and adhesion-mediating discoidin domain receptor 1 (DDR1) in modulating GBM therapy resistanc
Externí odkaz:
https://doaj.org/article/8ca7cfecc7974b7baf61298ff2fc4784
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 19, p 7277 (2020)
The intermediate filament synemin has been previously identified as novel regulator of cancer cell therapy resistance and DNA double strand break (DSB) repair. c-Abl tyrosine kinase is involved in both of these processes. Using PamGene technology, we
Externí odkaz:
https://doaj.org/article/3306ed14dd3846628f1385333bfa93b3
Autor:
Anne Vehlow, Nils Cordes
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 58:169-178
Cell adhesion to extracellular matrix proteins mediates resistance to radio- and chemotherapy by activating integrin signaling. In addition, mutual and cooperative interactions between integrin and growth factor receptor signaling contribute to the c
Autor:
Marie Pascaline Rahelivao, Ingmar Bauer, Tilo Lübken, Olga Kataeva, Anne Vehlow, Nils Cordes, Hans‐Joachim Knölker
Publikováno v:
European Journal of Organic Chemistry. 2022
Publikováno v:
Cancers
Volume 13
Issue 21
Cancers, Vol 13, Iss 5337, p 5337 (2021)
Cancers 13(2021), 5337
Volume 13
Issue 21
Cancers, Vol 13, Iss 5337, p 5337 (2021)
Cancers 13(2021), 5337
Simple Summary Glioblastoma patients suffer from a poor prognosis with a limited survival of just a few months. Incurability of this tumor mainly results from glioblastoma cell invasiveness as well as therapy resistance. A better understanding of the
Publikováno v:
Neuro-Oncology (2022), noac237
Background Glioblastoma (GBM) is a fast-growing primary brain tumor characterized by high invasiveness and resistance. This results in poor patient survival. Resistance is caused by many factors, including cell-extracellular matrix (ECM) interactions
Publikováno v:
Cancer Drug Discovery and Development ISBN: 9783030497002
The development and clinical implementation of novel therapeutics for the improvement of cancer patient survival is based on innovative and reproducible translational research. Despite extensive efforts from large-scale preclinical initiatives, many
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc908dd954b4eeab203cd2d80f80335c
https://doi.org/10.1007/978-3-030-49701-9_6
https://doi.org/10.1007/978-3-030-49701-9_6