Výsledky vyhledávání - "Anne Vaahtokari"

Akademický článek

Identification of novel p53 pathway activating small-molecule compounds reveals unexpected similarities with known therapeutic agents.

Autor: Karita Peltonen, Laureen Colis, Hester Liu, Sari Jäämaa, Henna M Moore, Juulia Enbäck, Pirjo Laakkonen, Anne Vaahtokari, Richard J Jones, Taija M af Hällström, Marikki Laiho

Publikováno v: PLoS ONE, Vol 5, Iss 9, p e12996 (2010)

Manipulation of the activity of the p53 tumor suppressor pathway has demonstrated potential benefit in preclinical mouse tumor models and has entered human clinical trials. We describe here an improved, extensive small-molecule chemical compound libr

Externí odkaz: https://doaj.org/article/ea4046a4634841ed92099e4f7335fd74

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PML‐like subnuclear bodies, containing XRCC1, juxtaposed to DNA replication‐based single‐strand breaks

Autor: Jurek Dobrucki, Oskar Szelest, Kamil Solarczyk, Magdalena Tworzydło, Christoph Cremer, Magdalena Kordon, Krzysztof Berniak, Sebastian Wachsmann-Hogiu, Aleksander Szczurek, Anne Vaahtokari, Thoru Pederson

Publikováno v: The FASEB Journal. 33:2301-2313

DNA lesions induce recruitment and accumulation of various repair factors, resulting in formation of discrete nuclear foci. Using superresolution fluorescence microscopy as well as live cell and quantitative imaging, we demonstrate that X-ray repair

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7503dd669f225e1204fb253acbbaa4ae
https://doi.org/10.1096/fj.201801379r

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Fluoxetine targets early progenitor cells in the adult brain

Autor: Juan M. Encinas, Grigori Enikolopov, Anne Vaahtokari

Publikováno v: Proceedings of the National Academy of Sciences. 103:8233-8238

Chronic treatment with antidepressants increases neurogenesis in the adult hippocampus. This increase in the production of new neurons may be required for the behavioral effects of antidepressants. However, it is not known which class of cells within

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46c216b1b1386247d5ef158dacefa32e
https://doi.org/10.1073/pnas.0601992103

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SRF selectively controls tip cell invasive behavior in angiogenesis

Autor: Ian Rosewell, Markus Fruttiger, Raquel Blanco, Irene M. Aspalter, Elena Mylonas, Holger Gerhardt, Nicolas Diguet, Virgine Penard-Lacronique, Zhenlin Li, Jacqueline Gao-Li, Anne Vaahtokari, Natalia Kazakova, Jocelyne Blanc, Mathias Mericskay, Ara Parlakian, Claudio A. Franco

Publikováno v: Development (Cambridge, England)
Development (Cambridge, England), Company of Biologists, 2013, 140 (11), pp.2321-2333. ⟨10.1242/dev.091074⟩
Development
Development (Cambridge, England), 2013, 140 (11), pp.2321-2333. ⟨10.1242/dev.091074⟩

International audience; Efficient angiogenic sprouting is essential for embryonic, postnatal and tumor development. Serum response factor (SRF) is known to be important for embryonic vascular development. Here, we studied the effect of inducible endo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::690b206fbd8456a7dfedc2d405a26c1e
https://hal.archives-ouvertes.fr/hal-01545744

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Molecular mechanisms of cell and tissue interactions during early tooth development

Autor: Irma Thesleff, Adrian K. Jowett, Anne Vaahtokari, Seppo Vainio

Publikováno v: The Anatomical Record. 245:151-161

Background Morphogenesis and cell differentiation during the development of all organs, including the tooth, are regulated by interactions between cells and tissues. The developing tooth is one of the organs in which the molecular mechanisms of such

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58b120b86a66c9167c5bd14a87a62755
https://doi.org/10.1002/(sici)1097-0185(199606)245:2<151::aid-ar4>3.0.co

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Transient Expression of Type III Collagen by Odontoblasts: Developmental Changes in the Distribution of Pro-α1 (III) and Pro-α1 (I) Collagen mRNAs in Dental Tissues

Autor: Minna Sandberg, Irma Thesleff, Pirjo-Liisa Lukinmaa, Anne Vaahtokari, Seppo Vainio, Janna Waltimo

Publikováno v: Matrix. 13:503-515

The expression of pro-alpha 1(III) and pro-alpha 1(I) collagen mRNAs in mouse and human dental tissues during tooth development and after its completion was analyzed by in situ hybridization, with use of [35S]-labeled RNA probes. The expression of pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80d002e3b144f53edcb348b0aaa26034
https://doi.org/10.1016/s0934-8832(11)80116-2

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Identification of Novel p53 Pathway Activating Small-Molecule Compounds Reveals Unexpected Similarities with Known Therapeutic Agents

Autor: Marikki Laiho, Pirjo Laakkonen, Henna M. Moore, Anne Vaahtokari, Sari Jäämaa, Hester Liu, Karita Peltonen, Richard J. Jones, Taija af Hällström, Juulia Enbäck, Laureen Colis

Publikováno v: PLoS ONE
PLoS ONE, Vol 5, Iss 9, p e12996 (2010)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aa1a5fd0ae80096e8eab0a23c83c850
http://europepmc.org/articles/PMC2946317

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Expression of Type I Collagen Pro-α2 Chain mRNA in Adult Human Permanent Teeth as Revealed by in situ Hybridization

Autor: Irma Thesleff, Pirjo-Liisa Lukinmaa, Seppo Vainio, Anne Vaahtokari

Publikováno v: Journal of Dental Research. 71:36-42

The expression of the gene COL1A2, coding for the pro-α2chain of type I pro-collagen, was analyzed in fully developed human permanent teeth. The teeth were fixed with formalin, demineralized with EDTA for about ten weeks, and embedded in paraffin. P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a111d80d2c3d55233064da3d7cd5a66
https://doi.org/10.1177/00220345920710010601

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Apoptosis in the developing tooth: association with an embryonic signaling center and suppression by EGF and FGF-4

Autor: Irma Thesleff, Anne Vaahtokari, Thomas Åberg

Publikováno v: Development (Cambridge, England). 122(1)

Apoptosis was localized in developing mouse teeth from initiation of morphogenesis to completion of cusp formation by using modified TUNEL method for serial sections and Nile Blue staining for whole mounts. Apoptosis was first detected at bud stage (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::356a57cf4f83f9fdf743dd30a0b2ba10
https://pubmed.ncbi.nlm.nih.gov/8565823

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The enamel knot as a signaling center in the developing mouse tooth

Autor: Soile Keränen, Irma Thesleff, Thomas Åberg, Jukka Jernvall, Anne Vaahtokari

Publikováno v: Mechanisms of development. 54(1)

Mammalian tooth forms are produced during development by folding of the enamel epithelium but the molecular mechanisms involved in the formation and patterning of tooth cusps are not understood. We now report that several key signaling molecules foun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71bfc3a7de81f348d4006a9fdd560ce0
https://pubmed.ncbi.nlm.nih.gov/8808404

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