Total synthesis of erythromycin B

Autor: Andrew S. Judd, Tsuneaki Hida, Philippe Breton, Stephen F. Martin, Philip R. Kym, Masayuki Yamashita, Erica Kraynack, Paul J. Hergenrother, W.‐C. Lee, Michael S. Loft, Anne V. Hodgson

Publikováno v: Tetrahedron. 63:5709-5729

We report the details of the first total synthesis of erythromycin B using two different strategies for the end game. The first of these follows a classical approach in which the desosamine and cladinose residues are sequentially appended to a macroc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0182a626edc3b18b6a226b76392dcf25
https://doi.org/10.1016/j.tet.2007.02.044

Characterization of the FAD Binding Domain of Cytochrome P450 Reductase

Autor: Henry W. Strobel, Anne V. Hodgson

Publikováno v: Archives of Biochemistry and Biophysics. 325:99-106

The redox potentials of FAD and FMN of Cytochrome P450 reductase (reductase) are equivalent in solution but differ by 138 mV when bound to reductase. The interaction of each flavin with its flavin binding domain confers the unique electron transferri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4376a2c7a2e38e2dd50311ad1d802dbc
https://doi.org/10.1006/abbi.1996.0012

The finished DNA sequence of human chromosome 12

Autor: Steven E, Scherer, Donna M, Muzny, Christian J, Buhay, Rui, Chen, Andrew, Cree, Yan, Ding, Shannon, Dugan-Rocha, Rachel, Gill, Preethi, Gunaratne, R Alan, Harris, Alicia C, Hawes, Judith, Hernandez, Anne V, Hodgson, Jennifer, Hume, Andrew, Jackson, Ziad Mohid, Khan, Christie, Kovar-Smith, Lora R, Lewis, Ryan J, Lozado, Michael L, Metzker, Aleksandar, Milosavljevic, George R, Miner, Kate T, Montgomery, Margaret B, Morgan, Lynne V, Nazareth, Graham, Scott, Erica, Sodergren, Xing-Zhi, Song, David, Steffen, Ruth C, Lovering, David A, Wheeler, Kim C, Worley, Yi, Yuan, Zhengdong, Zhang, Charles Q, Adams, M Ali, Ansari-Lari, Mulu, Ayele, Mary J, Brown, Guan, Chen, Zhijian, Chen, Kerstin P, Clerc-Blankenburg, Clay, Davis, Oliver, Delgado, Huyen H, Dinh, Heather, Draper, Manuel L, Gonzalez-Garay, Paul, Havlak, Laronda R, Jackson, Leni S, Jacob, Susan H, Kelly, Li, Li, Zhangwan, Li, Jing, Liu, Wen, Liu, Jing, Lu, Manjula, Maheshwari, Bao-Viet, Nguyen, Geoffrey O, Okwuonu, Shiran, Pasternak, Lesette M, Perez, Farah J H, Plopper, Jireh, Santibanez, Hua, Shen, Paul E, Tabor, Daniel, Verduzco, Lenee, Waldron, Qiaoyan, Wang, Gabrielle A, Williams, Jingkun, Zhang, Jianling, Zhou, Carlana C, Allen, Anita G, Amin, Vivian, Anyalebechi, Michael, Bailey, Joseph A, Barbaria, Kesha E, Bimage, Nathaniel P, Bryant, Paula E, Burch, Carrie E, Burkett, Kevin L, Burrell, Eliana, Calderon, Veronica, Cardenas, Kelvin, Carter, Kristal, Casias, Iracema, Cavazos, Sandra R, Cavazos, Heather, Ceasar, Joseph, Chacko, Sheryl N, Chan, Dean, Chavez, Constantine, Christopoulos, Joseph, Chu, Raynard, Cockrell, Caroline D, Cox, Michelle, Dang, Stephanie R, Dathorne, Robert, David, Candi Mon'Et, Davis, Latarsha, Davy-Carroll, Denise R, Deshazo, Jeremy E, Donlin, Lisa, D'Souza, Kristy A, Eaves, Amy, Egan, Alexandra J, Emery-Cohen, Michael, Escotto, Nicole, Flagg, Lisa D, Forbes, Abdul M, Gabisi, Melissa, Garza, Cerissa, Hamilton, Nicholas, Henderson, Omar, Hernandez, Sandra, Hines, Marilyn E, Hogues, Mei, Huang, DeVincent G, Idlebird, Rudy, Johnson, Angela, Jolivet, Sally, Jones, Ryan, Kagan, Laquisha M, King, Belita, Leal, Heather, Lebow, Sandra, Lee, Jaclyn M, LeVan, Lakeshia C, Lewis, Pamela, London, Lorna M, Lorensuhewa, Hermela, Loulseged, Demetria A, Lovett, Alice, Lucier, Raymond L, Lucier, Jie, Ma, Renita C, Madu, Patricia, Mapua, Ashley D, Martindale, Evangelina, Martinez, Elizabeth, Massey, Samantha, Mawhiney, Michael G, Meador, Sylvia, Mendez, Christian, Mercado, Iracema C, Mercado, Christina E, Merritt, Zachary L, Miner, Emmanuel, Minja, Teresa, Mitchell, Farida, Mohabbat, Khatera, Mohabbat, Baize, Montgomery, Niki, Moore, Sidney, Morris, Mala, Munidasa, Robin N, Ngo, Ngoc B, Nguyen, Elizabeth, Nickerson, Ogechi O, Nwaokelemeh, Stanley, Nwokenkwo, Melissa, Obregon, Maryann, Oguh, Njideka, Oragunye, Rodolfo J, Oviedo, Bridgette J, Parish, David N, Parker, Julia, Parrish, Kenya L, Parks, Heidie A, Paul, Brett A, Payton, Agapito, Perez, William, Perrin, Adam, Pickens, Eltrick L, Primus, Ling-Ling, Pu, Maria, Puazo, Miyo M, Quiles, Juana B, Quiroz, Dina, Rabata, Kacy, Reeves, San Juana, Ruiz, Hongmei, Shao, Ida, Sisson, Titilola, Sonaike, Richard P, Sorelle, Angelica E, Sutton, Amanda F, Svatek, Leah Anne, Svetz, Kavitha S, Tamerisa, Tineace R, Taylor, Brian, Teague, Nicole, Thomas, Rachel D, Thorn, Zulma Y, Trejos, Brenda K, Trevino, Ogechi N, Ukegbu, Jeremy B, Urban, Lydia I, Vasquez, Virginia A, Vera, Donna M, Villasana, Ling, Wang, Stephanie, Ward-Moore, James T, Warren, Xuehong, Wei, Flower, White, Angela L, Williamson, Regina, Wleczyk, Hailey S, Wooden, Steven H, Wooden, Jennifer, Yen, Lillienne, Yoon, Vivienne, Yoon, Sara E, Zorrilla, David, Nelson, Raju, Kucherlapati, George, Weinstock, Richard A, Gibbs

Publikováno v: Nature. 440(7082)

Human chromosome 12 contains more than 1,400 coding genes and 487 loci that have been directly implicated in human disease. The q arm of chromosome 12 contains one of the largest blocks of linkage disequilibrium found in the human genome. Here we pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b388f525fc0ae54d0bb314d806450da4
https://pubmed.ncbi.nlm.nih.gov/16541075

Expression of multiple forms of brain cytochrome P450

Autor: Huamin Wang, Jun Geng, Henry W. Strobel, David Sequeira, Anne V. Hodgson, Sijiu Shen, Arthur Bergh, Hidenori Kawashima

Publikováno v: Toxicology letters.

Multiple forms of cytochrome P450 (P450) in brain tissue have been demonstrated to be expressible in brain tissue using polymerase chain reaction (PCR) techniques, Northern blotting, hydroxylation activity assessment and cloning approaches. The antid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::959ad216b1c6e298553f50800f17f474
https://pubmed.ncbi.nlm.nih.gov/8597121

The Asymmetric Synthesis of Erythromycin B

Autor: Philip R. Kym, Stephen F. Martin, Michael S. Loft, Anne V. Hodgson, Tsuneaki Hida

Publikováno v: Journal of the American Chemical Society. 119:3193-3194

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::818f236a311b6531975b3de4ffaf8167
https://doi.org/10.1021/ja963575y