Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Anne V. Bedigian"'
Autor:
Sergi Garcia-Manyes, Eleonora Muro, Ulrike S. Eggert, Anne V. Bedigian, Sofia Sasse, Margaret Coughlin, G. Ekin Atilla-Gokcumen, Josep Relat-Goberna
Publikováno v:
Cell
Atilla-Gokcumen, G E, Muro, E, Relat-Goberna, J, Sasse, S, Bedigian, A, Coughlin, M L, Garcia-Manyes, S & Eggert, U S 2014, ' Dividing cells regulate their lipid composition and localization ', Cell, vol. 156, no. 3, pp. 428-439 . https://doi.org/10.1016/j.cell.2013.12.015
Atilla-Gokcumen, G E, Muro, E, Relat-Goberna, J, Sasse, S, Bedigian, A, Coughlin, M L, Garcia-Manyes, S & Eggert, U S 2014, ' Dividing cells regulate their lipid composition and localization ', Cell, vol. 156, no. 3, pp. 428-439 . https://doi.org/10.1016/j.cell.2013.12.015
Summary Although massive membrane rearrangements occur during cell division, little is known about specific roles that lipids might play in this process. We report that the lipidome changes with the cell cycle. LC-MS-based lipid profiling shows that
Autor:
Xin Zhang, Timothy J. Mitchison, Anne V. Bedigian, Ulrike S. Eggert, Wenchao Wang, Margaret Coughlin
Publikováno v:
Proceedings of the National Academy of Sciences. 109:12485-12490
Macromolecules enter cells by endocytosis and are sorted to different cellular destinations in early/sorting endosomes. The mechanism and regulation of sorting are poorly understood, although transitions between vesicular and tubular endosomes are im
Publikováno v:
Cytoskeleton (Hoboken, N.J.). 69(10)
Cytokinesis, the last step during cell division, is a highly coordinated process that involves the relay of signals from both the outside and inside of the cell. We have a basic understanding of how cells regulate internal events, but how cells respo
Publikováno v:
Journal of the American Chemical Society. 133(26)
Although cells undergo dramatic shape changes during cytokinesis, the role of the plasma membrane and lipids is poorly understood. We report that inactivation of glucosyl ceramide synthase (GCS), either by RNAi or with the small molecule PPMP, causes