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Akademický článek

Enhanced preservation of the human intestinal microbiota by ridinilazole, a novel Clostridium difficile-targeting antibacterial, compared to vancomycin.

Autor: Cheleste M Thorpe, Anne V Kane, Justin Chang, Albert Tai, Richard J Vickers, David R Snydman

Publikováno v: PLoS ONE, Vol 13, Iss 8, p e0199810 (2018)

Ridinilazole, a novel targeted antibacterial being developed for the treatment of C. difficile infection (CDI) and prevention of recurrence, was shown in a recent Phase 2 study to be superior to vancomycin with regard to the primary efficacy measure,

Externí odkaz: https://doaj.org/article/62f7690d5aaa4b0095f88aad8342d6f5

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Differential Response to the Course of Cryptosporidium parvum Infection and Its Impact on Epithelial Integrity in Differentiated versus Undifferentiated Human Intestinal Enteroids

Autor: Hymlaire Lamisere, Seema Bhalchandra, Anne V. Kane, Xi-Lei Zeng, Devons Mo, Walter Adams, Mary K. Estes, Honorine D. Ward

Publikováno v: Infect Immun

Cryptosporidium is a leading cause of diarrhea and death in young children and untreated AIDS patients and causes waterborne outbreaks. Pathogenic mechanisms underlying diarrhea and intestinal dysfunction are poorly understood. We previously develope

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::941713ad90ba8a7195c494355e42ba2a
https://doi.org/10.1128/iai.00397-22

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Akademický článek

Longitudinal Analysis of the Intestinal Microbiota in Persistently Stunted Young Children in South India.

Autor: Duy M Dinh, Balamurugan Ramadass, Deepthi Kattula, Rajiv Sarkar, Philip Braunstein, Albert Tai, Christine A Wanke, Soha Hassoun, Anne V Kane, Elena N Naumova, Gagandeep Kang, Honorine D Ward

Publikováno v: PLoS ONE, Vol 11, Iss 5, p e0155405 (2016)

Stunting or reduced linear growth is very prevalent in low-income countries. Recent studies have demonstrated a causal relationship between alterations in the gut microbiome and moderate or severe acute malnutrition in children in these countries. Ho

Externí odkaz: https://doaj.org/article/7a8a50ea4442437fa010e5d665dd918c

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Akademický článek

Diet- and Genetically-Induced Obesity Differentially Affect the Fecal Microbiome and Metabolome in Apc1638N Mice.

Autor: Anna C Pfalzer, Paula-Dene C Nesbeth, Laurence D Parnell, Lakshmanan K Iyer, Zhenhua Liu, Anne V Kane, C-Y Oliver Chen, Albert K Tai, Thomas A Bowman, Martin S Obin, Joel B Mason, Andrew S Greenberg, Sang-Woon Choi, Jacob Selhub, Ligi Paul, Jimmy W Crott

Publikováno v: PLoS ONE, Vol 10, Iss 8, p e0135758 (2015)

Obesity is a risk factor for colorectal cancer (CRC), and alterations in the colonic microbiome and metabolome may be mechanistically involved in this relationship. The relative contribution of diet and obesity per se are unclear. We compared the eff

Externí odkaz: https://doaj.org/article/cc36309c2341488d87ff417fd811eb56

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Akademický článek

High Prevalence of Spirochetosis in Cholera Patients, Bangladesh

Autor: Eric J. Nelson, Angela Tanudra, Ashrafuzzaman Chowdhury, Anne V. Kane, Firdausi Qadri, Stephen B. Calderwood, Jenifer Coburn, Andrew Camilli

Publikováno v: Emerging Infectious Diseases, Vol 15, Iss 4, Pp 571-573 (2009)

The microbes that accompany the etiologic agent of cholera, Vibrio cholerae, are only now being defined. In this study, spirochetes from the genus Brachyspira were identified at high titers in more than one third of cholera patients in Bangladesh. Sp

Externí odkaz: https://doaj.org/article/25e000c698f64c44a91f63598286e07f

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Abstract 17335: Dietary Carbohydrate Quality Affects Plasma Lipid Profile and the Microbiome

Autor: Nirupa R Matthan, Anne V Kane, William Evan Johnson, Solaiappan Manimaran, Tyler Faits, Alice H Lichtenstein

Publikováno v: Circulation. 132

Considerable data is available on the effect of carbohydrate (carb) quantity on CVD risk factors but data for carb quality is limited. Our objective was to determine the relative comparability for an isocaloric exchange of unrefined-carb (endosperm+g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d53d9f3c1455b2bb9f3e36c855357d26
https://doi.org/10.1161/circ.132.suppl_3.17335

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