Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Anne Thuery"'
Autor:
Jason Cosgrove, Mario Novkovic, Stefan Albrecht, Natalia B. Pikor, Zhaoukun Zhou, Lucas Onder, Urs Mörbe, Jovana Cupovic, Helen Miller, Kieran Alden, Anne Thuery, Peter O’Toole, Rita Pinter, Simon Jarrett, Emily Taylor, Daniel Venetz, Manfred Heller, Mariagrazia Uguccioni, Daniel F. Legler, Charles J. Lacey, Andrew Coatesworth, Wojciech G. Polak, Tom Cupedo, Bénedicte Manoury, Marcus Thelen, Jens V. Stein, Marlene Wolf, Mark C. Leake, Jon Timmis, Burkhard Ludewig, Mark C. Coles
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Morphogens such as chemokines form gradients to direct graded responses and modulate cell behaviors. Here the authors show, using imaging and computer simulation, that the chemokine CXCL13 originated from follicular reticular cells in the lymph nodes
Externí odkaz:
https://doaj.org/article/a29fe9ea7a8d465093c19a3301a148f3
Autor:
Urs Mörbe, Rita Pinter, Mariagrazia Uguccioni, Charles J.N. Lacey, Mark Coles, Marcus Thelen, Mark C. Leake, Zhaoukun Zhou, Natalia Pikor, Jason Cosgrove, Tom Cupedo, Anne Thuery, Jens V. Stein, Jon Timmis, Jovana Cupovic, Stefan Albrecht, Manfred Heller, Bénédicte Manoury, Kieran Alden, Mario Novkovic, Daniel F. Legler, Helen Miller, Burkhard Ludewig, Wojciech G. Polak, Marlene Wolf, Andrew Coatesworth, Daniel Venetz, Lucas Onder, Emily Taylor, Peter O'Toole, Simon Jarrett
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Cosgrove, Jason; Novkovic, Mario; Albrecht, Stefan; Pikor, Natalia B; Zhou, Zhaoukun; Onder, Lucas; Mörbe, Urs; Cupovic, Jovana; Miller, Helen; Alden, Kieran; Thuery, Anne; O'Toole, Peter; Pinter, Rita; Jarrett, Simon; Taylor, Emily; Venetz, Daniel; Heller, Manfred; Uguccioni, Mariagrazia; Legler, Daniel F; Lacey, Charles J; ... (2020). B cell zone reticular cell microenvironments shape CXCL13 gradient formation. Nature Communications, 11(1), p. 3677. Springer Nature 10.1038/s41467-020-17135-2
Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11, ⟨10.1038/s41467-020-17135-2⟩
Nature Communications, 11(1):3677. Nature Publishing Group
Cosgrove, Jason; Novkovic, Mario; Albrecht, Stefan; Pikor, Natalia B; Zhou, Zhaoukun; Onder, Lucas; Mörbe, Urs; Cupovic, Jovana; Miller, Helen; Alden, Kieran; Thuery, Anne; O'Toole, Peter; Pinter, Rita; Jarrett, Simon; Taylor, Emily; Venetz, Daniel; Heller, Manfred; Uguccioni, Mariagrazia; Legler, Daniel F; Lacey, Charles J; ... (2020). B cell zone reticular cell microenvironments shape CXCL13 gradient formation. Nature Communications, 11(1), p. 3677. Springer Nature 10.1038/s41467-020-17135-2
Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11, ⟨10.1038/s41467-020-17135-2⟩
Nature Communications, 11(1):3677. Nature Publishing Group
Through the formation of concentration gradients, morphogens drive graded responses to extracellular signals, thereby fine-tuning cell behaviors in complex tissues. Here we show that the chemokine CXCL13 forms both soluble and immobilized gradients.
Autor:
Simon Wöhrle, Andreas Weiss, Moriko Ito, Audrey Kauffmann, Masato Murakami, Zainab Jagani, Anne Thuery, Beatrice Bauer-Probst, Flavia Reimann, Christelle Stamm, Astrid Pornon, Vincent Romanet, Vito Guagnano, Thomas Brümmendorf, William R Sellers, Francesco Hofmann, Charles W M Roberts, Diana Graus Porta
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77652 (2013)
Malignant rhabdoid tumors (MRTs) are aggressive pediatric cancers arising in brain, kidney and soft tissues, which are characterized by loss of the tumor suppressor SNF5/SMARCB1. MRTs are poorly responsive to chemotherapy and thus a high unmet clinic
Externí odkaz:
https://doaj.org/article/5ddabf7e37d840fe9ce647ad449900b5
Autor:
Mark Coles, Zhi Li, Anne Thuery, Natalie Papazian, Priyanka Narang, Kerim Hoorweg, Tom Cupedo, David R. Withers
Publikováno v:
Journal of Immunology, 195(9), 4257-4263. American Association of Immunologists
Adaptive immunity critically depends on the functional compartmentalization of secondary lymphoid organs. Mesenchymal stromal cells create and maintain specialized niches that support survival, activation, and expansion of T and B cells, and integrat
Autor:
Christine Henninger, Anne Thuery, Olivier Bonny, Simon Wöhrle, Noemie Beluch, Francesco Hofmann, Vito Guagnano, Nancy E. Hynes, William R. Sellers, Diana Graus Porta, Michaela Kneissel
Publikováno v:
Journal of Bone and Mineral Research. 28:899-911
Fibroblast growth factor 23 (FGF23) is a circulating factor secreted by osteocytes that is essential for phosphate homeostasis. In kidney proximal tubular cells FGF23 inhibits phosphate reabsorption and leads to decreased synthesis and enhanced catab
Autor:
Noemie Beluch, Christelle Stamm, Swann Gaulis, Simon Wöhrle, Marcel Scheibler, Diana Graus-Porta, Francesco Hofmann, Olivier Bonny, Bernd Kinzel, William R. Sellers, Nancy E. Hynes, Joseph Brueggen, Anne Thuery, Matthias Müller
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 26(10)
The functional interaction between fibroblast growth factor 23 (FGF-23) and Klotho in the control of vitamin D and phosphate homeostasis is manifested by the largely overlapping phenotypes of Fgf23- and Klotho-deficient mouse models. However, to date
Autor:
Charles W. M. Roberts, Flavia Reimann, Simon Wöhrle, Audrey Kauffmann, Thomas Brümmendorf, Masato Murakami, Vito Guagnano, Andreas Weiss, Zainab Jagani, Astrid Pornon, Beatrice Bauer-Probst, Vincent Romanet, Christelle Stamm, Moriko Ito, William R. Sellers, Francesco Hofmann, Diana Graus Porta, Anne Thuery
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 10, p e77652 (2013)
PLoS ONE, Vol 8, Iss 10, p e77652 (2013)
Malignant rhabdoid tumors (MRTs) are aggressive pediatric cancers arising in brain, kidney and soft tissues, which are characterized by loss of the tumor suppressor SNF5/SMARCB1. MRTs are poorly responsive to chemotherapy and thus a high unmet clinic
Autor:
Wöhrle, Simon1, Weiss, Andreas1, Ito, Moriko1, Kauffmann, Audrey1, Murakami, Masato1, Jagani, Zainab2, Thuery, Anne1, Bauer-Probst, Beatrice1, Reimann, Flavia1, Stamm, Christelle1, Pornon, Astrid1, Romanet, Vincent1, Guagnano, Vito1, Brümmendorf, Thomas1, Sellers, William R.2, Hofmann, Francesco1, Roberts, Charles W. M.3, Graus Porta, Diana1 diana.graus_porta@novartis.com
Publikováno v:
PLoS ONE. Oct2013, Vol. 8 Issue 10, p1-11. 11p.
Autor:
Cosgrove, Jason, Novkovic, Mario, Albrecht, Stefan, Pikor, Natalia B., Zhou, Zhaoukun, Onder, Lucas, Mörbe, Urs, Cupovic, Jovana, Miller, Helen, Alden, Kieran, Thuery, Anne, O'Toole, Peter, Pinter, Rita, Jarrett, Simon, Taylor, Emily, Venetz, Daniel, Heller, Manfred, Uguccioni, Mariagrazia, Legler, Daniel F., Lacey, Charles J.
Publikováno v:
Nature Communications; 7/22/2020, Vol. 11 Issue 1, p1-15, 15p