Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Anne T. Collins"'
Autor:
Conor M. Devlin, Fiona M. Frame, Leanne K. Archer, Vincent M. Mann, Hannah Walker, Matthew S. Simms, Daniel M. Berney, Anne T. Collins, Norman J. Maitland
Publikováno v:
European Urology Open Science, Vol 21, Iss , Pp 29-32 (2020)
Externí odkaz:
https://doaj.org/article/2769066dae164640bd16b32114735e25
Autor:
Anne T. Collins, Shona H. Lang
Publikováno v:
PeerJ, Vol 6, p e5981 (2018)
Patient-derived xenograft (PDX) models are increasingly being used in oncology drug development because they offer greater predictive value than traditional cell line models. Using novel tools to critique model validity and reliability we performed a
Externí odkaz:
https://doaj.org/article/b0b2bcd01cb44c54a007ca3c9fcfb0da
Autor:
Jayant K. Rane, Alastair P. Droop, Davide Pellacani, Euan S. Polson, Matthew S. Simms, Anne T. Collins, Leo S.D. Caves, Norman J. Maitland
Publikováno v:
Stem Cell Reports, Vol 2, Iss 2, Pp 180-188 (2014)
Human epithelia are organized in a hierarchical structure, where stem cells generate terminally differentiated cells via intermediate progenitors. This two-step differentiation process is conserved in all tissues, but it is not known whether a common
Externí odkaz:
https://doaj.org/article/224cf99a347c42e9aa68aa3823822cce
Autor:
Anne T. Collins, Norman J. Maitland, Pui-Kai Li, Chenglong Li, Somsundaram Chettiar, Deepak Bhasin, Matthew Simms, Vincent M. Mann, Greta Rodrigues, Michael J. Stower, Paul A. Berry, Paula Kroon
PDF file, 84K, 4.IL-6 levels (pg/ml/103 cells) in the supernatant of prostatic primary cultures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d6002e5aeeb9c48dc8c76fa3608fa0c
https://doi.org/10.1158/0008-5472.22404449.v1
https://doi.org/10.1158/0008-5472.22404449.v1
Autor:
Anne T. Collins, Norman J. Maitland, Pui-Kai Li, Chenglong Li, Somsundaram Chettiar, Deepak Bhasin, Matthew Simms, Vincent M. Mann, Greta Rodrigues, Michael J. Stower, Paul A. Berry, Paula Kroon
Interleukin (IL)-6 overexpression and constitutive STAT3 activation occur in many cancers, including prostate cancer. However, their contribution to prostate stem and progenitor cells has not been explored. In this study, we show that stem-like cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3759079a1cd74807e03543c8d654275f
https://doi.org/10.1158/0008-5472.c.6506609
https://doi.org/10.1158/0008-5472.c.6506609
Autor:
Anne T. Collins, Norman J. Maitland, Pui-Kai Li, Chenglong Li, Somsundaram Chettiar, Deepak Bhasin, Matthew Simms, Vincent M. Mann, Greta Rodrigues, Michael J. Stower, Paul A. Berry, Paula Kroon
PDF file, 8K, 3.mRNA expression of IL-6 (fold change) in prostatic primary cultures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dfe8b03c975ddbe5c5743ba5a98750d
https://doi.org/10.1158/0008-5472.22404452
https://doi.org/10.1158/0008-5472.22404452
Autor:
Anne T. Collins, Norman J. Maitland, Pui-Kai Li, Chenglong Li, Somsundaram Chettiar, Deepak Bhasin, Matthew Simms, Vincent M. Mann, Greta Rodrigues, Michael J. Stower, Paul A. Berry, Paula Kroon
PDF file, 7896K, A. Histology of mouse xenograft. H&E stain of a mouse xenograft derived from a patient with castrate-resistant prostate cancer. Small glandular structures are apparent with large, prominent nucleoli within sheets of undifferentiated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9b53d35697d0aaec54104f3fe6aec43
https://doi.org/10.1158/0008-5472.22404455.v1
https://doi.org/10.1158/0008-5472.22404455.v1
Autor:
Vincent M. Mann, Norman J. Maitland, Fiona M. Frame, Conor M Devlin, Leanne K. Archer, Hannah F. Walker, Daniel M. Berney, Matthew S. Simms, Anne T. Collins
Publikováno v:
European Urology Open Science, Vol 21, Iss, Pp 29-32 (2020)
European Urology Open Science
European Urology Open Science
Autor:
Connie J. Eaves, Fiona M. Frame, Vincent M. Mann, Norman J. Maitland, Alastair Droop, Davide Pellacani, Anne T. Collins, Matthew S. Simms
Publikováno v:
British Journal of Cancer
BACKGROUND: Human prostate cancers display numerous DNA methylation changes compared to normal tissue samples. However, definitive identification of features related to the cells' malignant status has been compromised by the predominance of cells wit
Autor:
Robert L. Vessella, Nora M. Navone, Frédéric R. Santer, Anne T. Collins, Yuzhuo Wang, Peter Shepherd, Rute B. Marques, Wytske M. van Weerden, Cyril A. Rentsch, Eva Corey, William Nathaniel Brennen, Elizabeth D. Williams, Norman J. Maitland, Jeroen T. Buijs, Renea A. Taylor, Ariel H Achtman, Tjalling Bosse, Zoran Culig, Holly M. Nguyen, Gabri van der Pluijm, Gail P. Risbridger, Dong Lin, Hui Xue, Mark Buzza, John T. Isaacs, Lukas Bubendorf, George N. Thalmann, Patrizia Moser, Michelle M. Kouspou, Corrina M.A. de Ridder, Eleni Efstathiou
Publikováno v:
Prostate, 78(16), 1262-1282. Wiley-Liss Inc.
Prostate, 78(16), 1262-1282. WILEY
Prostate, 78(16), 1262-1282. WILEY
BACKGROUND: While it has been challenging to establish prostate cancer patient-derived xenografts (PDXs), with a take rate of 10-40% and long latency time, multiple groups throughout the world have developed methods for the successful establishment o