Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Anne T. Bruinvels"'
Autor:
S Geisse, Anne T. Bruinvels, Bernd Sommer, Mark D. Tricklebank, Daniel Hoyer, Lucien Gazi, E. Schüpbach, Philippe Schoeffter, M Danzeisen, I. Bobirnac
Publikováno v:
British Journal of Pharmacology. 124:889-896
1. Dopamine D4 receptor antagonists are being developed by several pharmaceutical companies as putative novel antipsychotics, possibly with low propensity to side-effects. Two such compounds, L-745,870 and U-101958 have been recently introduced. 2. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9beb34fff9900f03be289828f507c57d
https://doi.org/10.1038/sj.bjp.0701921
https://doi.org/10.1038/sj.bjp.0701921
Publikováno v:
Molecular Brain Research. 21:19-29
Quantitative receptor autoradiography was used to examine the 5-hydroxytryptamine (5-HT, serotonin) binding sites labelled with serotonin -5-O- carboxymethyl-glycyl-[ 125 I]tyrosinamide ([125I]GTI) in human and guinea-pig brain. Competition experimen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a05675ae054a52d03096cb4b3c4a29d7
https://doi.org/10.1016/0169-328x(94)90374-3
https://doi.org/10.1016/0169-328x(94)90374-3
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 348:403-410
In the present experiments we investigated endothelin (ET) receptors in the human coronary artery, and in ventricular and atrial muscle using quantitative receptor autoradiography. Displacement of [125I]Sf6b (Sarafotoxin S6b) (30 pM)- and [125I]ET-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4620c507fce1b421f73b40b2c7bf407c
https://doi.org/10.1007/bf00171340
https://doi.org/10.1007/bf00171340
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 347:569-582
The regional distribution and the pharmacology of the binding sites labelled with the novel 5-hydroxytryptamine (serotonin) 5-HT1B/1D selective radioligand serotonin-O-carboxy-methyl-glycyl-[125I]tyrosinamide (abbreviated [125I]GTI for the sake of si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ca6c2a14634f996026240d75af0556f
https://doi.org/10.1007/bf00166939
https://doi.org/10.1007/bf00166939
Publikováno v:
Neuroscience. 53:465-473
Quantitative in vitro receptor autoradiography was used to characterize the [ 3 H]5-hydroxytryptamine binding sites which are not sensitive to 8-hydroxy-2-(di- N -propylamino)tetralin, mesulergine and serotonin-5- O -car☐y-methyl-glycyl-tyrosinamid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52be84c9ac048b1bd9c45a274211a7b0
https://doi.org/10.1016/0306-4522(93)90210-7
https://doi.org/10.1016/0306-4522(93)90210-7
Publikováno v:
Journal of Medicinal Chemistry. 35:3448-3462
Hydropathicity analysis of 39 G-protein-coupled receptors (GPCR) reveals seven hydrophobic stretches corresponding to membrane spanning alpha-helices. The alignment of the primary sequences shows a high degree of homology in the GPCR transmembrane re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0bb9e7c55e7741981529c065c0bf9fd
https://doi.org/10.1021/jm00097a002
https://doi.org/10.1021/jm00097a002
Publikováno v:
Neurochemistry International. 19:397-406
A basic pharmacophore of the 5-HT 1D agonist recognition site was defined from a conformation-activity relationship study of 11 different agonists. It consists of an aromatic ring and a nitrogen atom in well defined relative positions. The contributi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::003449c25b07ed8a7e01ebd3298545ef
https://doi.org/10.1016/0197-0186(91)90056-j
https://doi.org/10.1016/0197-0186(91)90056-j
Publikováno v:
European Journal of Pharmacology. 202:89-91
The novel iodinated radioligand, scrotonin-5-O-carboxymcthyl-glycyl[ 125 I]tyrosinamide. was used for binding studies with membranes of human substantia nigra. Evidence is provided for the existence in this tissue of a homogeneous population of recog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7fabb3c0c1f3a31e093fd16d85ea01d
https://doi.org/10.1016/0014-2999(91)90257-q
https://doi.org/10.1016/0014-2999(91)90257-q
Autor:
Bernhard Landwehrmeyer, José Palacios, Anne T. Bruinvels, T.A. Branchek, M.M. Durkin, Daniel Hoyer, Eric L. Gustafson, Guadalupe Mengod
Publikováno v:
Neuropharmacology. 33(3-4)
In situ hybridization histochemistry (ISHH) was used to study the distribution of various 5-HT1 receptor messenger RNAs (mRNA) in the mammalian nervous system. Since the cDNAs encoding the different 5-HT1 receptors, have not been cloned in one single
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90b772ac3eee0b43814ae736dbe3e742
https://pubmed.ncbi.nlm.nih.gov/7984275
https://pubmed.ncbi.nlm.nih.gov/7984275
Publikováno v:
Medical Science Symposia Series ISBN: 9789401048491
In spite of the title, this paper will address issues about the possible similarities and differences between what has initially been designated as 5-HTB5-HTIDand 5-HT,-like receptors, since in view of recent cloning work on 5-HTB5-HTpa5-HTI„s5-HTF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39526318d20c359a40ce7b98e3d3af32
https://doi.org/10.1007/978-94-011-1920-7_10
https://doi.org/10.1007/978-94-011-1920-7_10
