Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Anne Steininger"'
Autor:
Anne Steininger, Grit Ebert, Benjamin V. Becker, Chalid Assaf, Markus Möbs, Christian A. Schmidt, Piotr Grabarczyk, Lars R. Jensen, Grzegorz K. Przybylski, Matthias Port, Andreas W. Kuss, Reinhard Ullmann
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
In classical models of tumorigenesis, the accumulation of tumor promoting chromosomal aberrations is described as a gradual process. Next-generation sequencing-based methods have recently revealed complex patterns of chromosomal aberrations, which ar
Externí odkaz:
https://doaj.org/article/5eb923c91bc748f2aa8e9d9b0088e1a8
Autor:
Markus Möbs, Ahmed Haider, Wolfram Sterry, Anne Steininger, Michael Hummel, Reinhard Ullmann, Staffan Vandersee, Chalid Assaf, Marc Beyer, Lora Dimitrova, Dido Lenze
Publikováno v:
Journal of Investigative Dermatology. 136:2287-2296
The key role of RUNX3 in physiological T-cell differentiation has been extensively documented. However, information on its relevance for the development of human T-cell lymphomas or leukemias is scarce. Here, we show that alterations of RUNX3 by eith
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3cf0e0f415d1de6e2eba8baee9e261f
https://doi.org/10.1016/j.jid.2016.05.126
https://doi.org/10.1016/j.jid.2016.05.126
Autor:
Markus Möbs, Piotr Grabarczyk, Matthias Port, Grzegorz K. Przybylski, Anne Steininger, Benjamin Valentin Becker, Andreas W. Kuss, Lars R. Jensen, Chalid Assaf, Grit Ebert, Reinhard Ullmann, Christian Schmidt
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 8 (2018)
Frontiers in Oncology, Vol 8 (2018)
In classical models of tumorigenesis, the accumulation of tumor promoting chromosomal aberrations is described as a gradual process. Next-generation sequencing-based methods have recently revealed complex patterns of chromosomal aberrations, which ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06f7a4cf57fc8edeecf5448f5d32523a
https://doi.org/10.3389/fonc.2018.00183
https://doi.org/10.3389/fonc.2018.00183
Autor:
Reinhard Ullmann, Nuran Sabir, Dilihan Gumus, Mine Cinbiş, Anne Steininger, Baki Yagci, Osvaldo M. Mutchinick, Emre Tepeli, C. Nur Semerci, Muhterem Bahçe, Serap Özden, Jazmín Arteaga
Publikováno v:
American Journal of Medical Genetics Part A. :1724-1729
We report on a patient with partial monosomy 6p and partial trisomy 12q identified by fluorescent in situ hybridization (FISH) and array-based comparative genomic hybridization (aCGH). She had a complex phenotype characterized by mental retardation (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2229de342c59a21c30d865462798b798
https://doi.org/10.1002/ajmg.a.33383
https://doi.org/10.1002/ajmg.a.33383
Autor:
Annette Grüters, Markus Schuelke, Christof Dame, Ines Müller, Heike Biebermann, Hans-Jürgen Christen, Carsten G. Bönnemann, Patricia Crock, Reinhard Ullmann, Hans-Hilger Ropers, Grit Ebert, Matthias Griese, Anne Steininger, Pamela Schrumpf, Sabine Jyrch, Dietz Rating, Jacqueline K. Hewitt, Juri Katchanov, Iva Stoeva, Sarah Schnittert-Hübener, Francis deZegher, Anne Thorwarth, Heiko Krude, Christoph Hübner, Gunnar Kleinau, Barbara Plecko, Klaus Kapelari, Sten A. Ivarsson, Knut Brockmann
Publikováno v:
Journal of Medical Genetics
BACKGROUND: NKX2-1 encodes a transcription factor with large impact on the development of brain, lung and thyroid. Germline mutations of NKX2-1 can lead to dysfunction and malformations of these organs. Starting from the largest coherent collection o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87c4bb0d75cc5953a338ec723c1f6671
https://www.zora.uzh.ch/id/eprint/104724/
https://www.zora.uzh.ch/id/eprint/104724/
Autor:
Grit, Ebert, Anne, Steininger, Robert, Weißmann, Vivien, Boldt, Allan, Lind-Thomsen, Jana, Grune, Stefan, Badelt, Melanie, Heßler, Matthias, Peiser, Manuel, Hitzler, Lars R, Jensen, Ines, Müller, Hao, Hu, Peter F, Arndt, Andreas W, Kuss, Katrin, Tebel, Reinhard, Ullmann
Publikováno v:
BMC Genomics
Background Segmental duplications (SDs) are not evenly distributed along chromosomes. The reasons for this biased susceptibility to SD insertion are poorly understood. Accumulation of SDs is associated with increased genomic instability, which can le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::780cf09ab0de42740eecfa96249f76a2
https://pubmed.ncbi.nlm.nih.gov/24973960
https://pubmed.ncbi.nlm.nih.gov/24973960
Autor:
Artur Muradyan, Vivien Boldt, Anne Steininger, Stephanie Stabentheiner, Katrin Tebel, Jürgen Kreutzberger, Ines Müller, Hannelore Madle, Helmut H. Popper, Reinhard Ullmann
Publikováno v:
Archives of pathologylaboratory medicine. 132(10)
The accumulation of chromosomal aberrations is a characteristic feature of tumor development. However, an understanding of tumorigenesis that assumes that changes in DNA copy number always cause equivalent changes in the corresponding RNA and protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6542c1b60128d644c6a751b4cdd3bfe
https://pubmed.ncbi.nlm.nih.gov/18834209
https://pubmed.ncbi.nlm.nih.gov/18834209
Publikováno v:
BMC Bioinformatics
Background The analysis of DNA copy number variants (CNV) has increasing impact in the field of genetic diagnostics and research. However, the interpretation of CNV data derived from high resolution array CGH or NGS platforms is complicated by the co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6cf5d947dcfe1e161954ba82c188aa6