Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Anne Sophie Heimes"'
Autor:
Kathrin Stewen, Annika Droste, Christian Ruckes, Tania Elger, Susanne Theis, Anne-Sophie Heimes, Mona Wanda Schmidt, Lina Judit Schiestl, Philip Herbert Klecker, Katrin Almstedt, Marcus Schmidt, Walburgis Brenner, Annette Hasenburg, Roxana Schwab
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35417- (2024)
Background: Modifiable lifestyle factors exert a substantial influence on the development of various diseases. The COVID-19 pandemic necessitated the implementation of containment measures to mitigate the viral spread, which affected the maintenance
Externí odkaz:
https://doaj.org/article/0314d6e361e94367923e2d2f24a6e487
Autor:
Roxana Schwab, Lina Judit Schiestl, Lorena Cascant Ortolano, Philip Herbert Klecker, Mona Wanda Schmidt, Katrin Almstedt, Anne-Sophie Heimes, Walburgis Brenner, Kathrin Stewen, Marcus Schmidt, Annette Hasenburg
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionVulvar cancer carries a favourable prognosis in early stages. However, therapeutic options for advanced or recurrent cases are limited despite a variety of therapeutic modalities, such as extensive surgical resection, chemotherapy, and ra
Externí odkaz:
https://doaj.org/article/54a202f43ba5407589087b76f8360978
Autor:
Ina Shehaj, Slavomir Krajnak, Katrin Almstedt, Yaman Degirmenci, Sophia Herzog, Antje Lebrecht, Valerie Catherine Linz, Roxana Schwab, Kathrin Stewen, Walburgis Brenner, Annette Hasenburg, Marcus Schmidt, Anne-Sophie Heimes
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1361 (2024)
Breast cancer (BC) poses a challenge in establishing new treatment strategies and identifying new prognostic and predictive markers due to the extensive genetic heterogeneity of BC. Very few studies have investigated the impact of mRNA expression of
Externí odkaz:
https://doaj.org/article/436bd216dafe4472bd66a3ed096dbda2
Autor:
Slavomir Krajnak, Jannis Patrik Trier, Pauline Friederike Heinzmann, Katharina Anic, Anne-Sophie Heimes, Amelie Loewe, Marcus Schmidt, Marco Johannes Battista, Annette Hasenburg, Walburgis Brenner
Publikováno v:
EXCLI Journal : Experimental and Clinical Sciences, Vol 22, Pp 114-130 (2023)
In metastatic breast cancer (MBC), PIK3CA mutations, activating the phosphatidylinositol 3-kinase (PI3K) signaling pathway seem to be associated with chemotherapy resistance and poor outcome. Inhibition of the PI3K signaling pathway may lead to sensi
Externí odkaz:
https://doaj.org/article/f53593c33c4d41c089131f2ffb937c14
Autor:
Anne-Sophie Heimes, Katrin Almstedt, Slavomir Krajnak, Anne Runkel, Annika Droste, Roxana Schwab, Kathrin Stewen, Antje Lebrecht, Marco J. Battista, Walburgis Brenner, Annette Hasenburg, Mathias Gehrmann, Jan G. Hengstler, Marcus Schmidt
Publikováno v:
Biomedicines, Vol 10, Iss 10, p 2656 (2022)
Background: Monoclonal antibodies against PD-1 or PD-L1 have been established in clinical practice for the treatment of both early and advanced/metastatic triple-negative breast cancer. Beyond the established immune checkpoints (ICPs) (PD-1 and CTLA-
Externí odkaz:
https://doaj.org/article/34dbf5ecf98d4a23af271fabb54d11b1
Autor:
Slavomir Krajnak, Jana Krajnakova, Katharina Anic, Katrin Almstedt, Anne-Sophie Heimes, Valerie Catherine Linz, Amelie Loewe, Mona Wanda Schmidt, Annette Hasenburg, Marcus Schmidt, Marco Johannes Battista
Publikováno v:
Breast Care. 18:97-105
Introduction: Metronomic chemotherapy (MCT) is increasingly used in oncology due to its favorable therapeutic index. There is still a lack of evidence for MCT in metastatic breast cancer (MBC). In this retrospective unicenter study, we demonstrated r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41bdc7538aa6bea1481a74d7f6fa4aba
https://doi.org/10.1159/000528042
https://doi.org/10.1159/000528042
Autor:
Marcus Schmidt, Veronika Weyer-Elberich, Jan G. Hengstler, Anne-Sophie Heimes, Katrin Almstedt, Aslihan Gerhold-Ay, Antje Lebrecht, Marco J. Battista, Annette Hasenburg, Ugur Sahin, Konstantine T. Kalogeras, Pirkko-Liisa Kellokumpu-Lehtinen, George Fountzilas, Ralph M. Wirtz, Heikki Joensuu
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-10 (2018)
Abstract Background The clinical importance of tumor-infiltrating cluster of differentiation 4 (CD4) T cells is incompletely understood in early breast cancer. We investigated the clinical significance of CD4, forkhead box P3 (FOXP3), and B cell attr
Externí odkaz:
https://doaj.org/article/da0cf538b47445d3a9ca8a1909d519c0
Autor:
Anne-Sophie Heimes, Annette Hasenburg
Publikováno v:
Frauenheilkunde up2date. 16:25-38
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27bc463ee1c7b3a11642970ef6e3eb32
https://doi.org/10.1055/a-1372-8146
https://doi.org/10.1055/a-1372-8146
Autor:
Katrin Almstedt, Lisa Krauthauser, Franziska Kappenberg, Daniel-Christoph Wagner, Anne-Sophie Heimes, Marco J. Battista, Katharina Anic, Slavomir Krajnak, Antje Lebrecht, Roxana Schwab, Walburgis Brenner, Wolfgang Weikel, Jörg Rahnenführer, Jan G. Hengstler, Wilfried Roth, Annette Hasenburg, Kathrin Stewen, Marcus Schmidt
Publikováno v:
Cancers
Volume 15
Issue 5
Pages: 1413
Volume 15
Issue 5
Pages: 1413
Background: Novel antibody-drug conjugates (ADCs) show activity in HER2-low advanced breast cancer. We examined differences in HER2 expression between primary tumors and distant metastases, particularly within the HER2-negative cohort (HER2-low and H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::214ca1fb93129d49d5ca221e64fb156c
https://doi.org/10.21203/rs.3.rs-2478913/v1
https://doi.org/10.21203/rs.3.rs-2478913/v1
Autor:
Katharina Anic, Sophie Birkert, Mona Wanda Schmidt, Valerie Catherine Linz, Anne-Sophie Heimes, Slavomir Krajnak, Roxana Schwab, Marcus Schmidt, Christiane Westphalen, Erik Kristoffer Hartmann, Annette Hasenburg, Marco Johannes Battista
Publikováno v:
Gerontology. 68:1101-1110
Background: We evaluated the prognostic impact of various global health assessment tools in patients older than 60 years with ovarian cancer (OC). Methods: G-8 geriatric screening tool (G-8 score), Lee Schonberg prognostic index, Eastern Cooperative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b941f2d7dd4c6d64fba28a1b3611eed9
https://doi.org/10.1159/000520328
https://doi.org/10.1159/000520328