Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Anne Sofie Busk Heitmann"'
Autor:
Malene Laage Ebstrup, Stine Lauritzen Sønder, Ditte Louise Fogde, Anne Sofie Busk Heitmann, Tiina Naumanen Dietrich, Catarina Dias, Marja Jäättelä, Kenji Maeda, Jesper Nylandsted
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2024)
Lysosomes are crucial organelles essential for various cellular processes, and any damage to them can severely compromise cell viability. This study uncovers a previously unrecognized function of the calcium- and phospholipid-binding protein Annexin
Externí odkaz:
https://doaj.org/article/bd1103947a9b433d9ba7b5a9098218ad
Autor:
Anna Mularski, Stine Lauritzen Sønder, Anne Sofie Busk Heitmann, Mayank Prakash Pandey, Himanshu Khandelia, Jesper Nylandsted, Adam Cohen Simonsen
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Efficient plasma membrane repair (PMR) is required to repair damage sustained in the cellular life cycle. The annexin family of proteins, involved in PMR, are activated by Ca2+ influx from extracellular media at the site of injury. Mechanist
Externí odkaz:
https://doaj.org/article/fc244366550b4d8d8d1720e03effac7a
Autor:
Swantje Christin Häger, Catarina Dias, Stine Lauritzen Sønder, André Vidas Olsen, Isabelle da Piedade, Anne Sofie Busk Heitmann, Elena Papaleo, Jesper Nylandsted
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Plasma membrane repair mechanisms are activated within seconds post-injury to promote rapid membrane resealing in eukaryotic cells and prevent cell death. However, less is known about the regeneration phase that follows and how cells respond
Externí odkaz:
https://doaj.org/article/99adb3dc3d88401b94736e0dc7c6ae80
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Plasma membrane repair is essential for eukaryotic cell life and is triggered by the influx of calcium through membrane wounds. Repair consists of sequential steps, with closure of the membrane hole being the key event that allows the cell t
Externí odkaz:
https://doaj.org/article/cb50f1d96543458da9d5ea6e6d198add
Autor:
Ali Asghar Hakami Zanjani, Anna Mularski, Anne Sofie Busk Heitmann, Catarina Dias, Michelle Ege Møller, Kenji Maeda, Jesper Nylandsted, Adam Cohen Simonsen, Himanshu Khandelia
Publikováno v:
Biophysical Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e66c274263d07b319da16ed81e0cae8b
https://doi.org/10.1016/j.bpj.2023.04.002
https://doi.org/10.1016/j.bpj.2023.04.002
Autor:
Adam Cohen Simonsen, Anna Mularski, Anne Sofie Busk Heitmann, Jesper Nylandsted, Stine Lauritzen Sønder
Publikováno v:
Mularski, A, Sønder, S L, Heitmann, A S B, Nylandsted, J & Simonsen, A C 2021, ' Simultaneous membrane binding of Annexin A4 and A5 suppresses 2D lattice formation while maintaining curvature induction ', Journal of Colloid and Interface Science, vol. 600, pp. 854-864 . https://doi.org/10.1016/j.jcis.2021.05.067
Hypothesis Annexin A4 and A5 (ANXA4, ANXA5), both shown to be required for efficient plasma membrane repair (PMR) in living cells, bind as trimers to anionic membranes in the presence of calcium. Both annexins induce membrane curvature and self-assem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbc71ad7de910bfd515ede799a07bb03
https://doi.org/10.1016/j.jcis.2021.05.067
https://doi.org/10.1016/j.jcis.2021.05.067
Autor:
Anne Sofie Busk Heitmann, Anna Mularski, Christoffer Iversen, Jesper Nylandsted, Frederik W. Lund, Catarina Dias, Adam Cohen Simonsen, Martin Berg Klenow
Publikováno v:
Berg Klenow, M, Iversen, C, Wendelboe Lund, F, Mularski, A, Busk Heitmann, A S, Dias, C, Nylandsted, J & Simonsen, A C 2021, ' Annexins A1 and A2 Accumulate and Are Immobilized at Cross-Linked Membrane-Membrane Interfaces ', Biochemistry, vol. 60, no. 16, pp. 1248-1259 . https://doi.org/10.1021/acs.biochem.1c00126
Rapid membrane repair is required to ensure cell survival after rupture of the plasma membrane. The annexin family of proteins is involved in plasma membrane repair (PMR) and is activated by the influx of Ca2+ from the extracellular medium at the sit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8087dd731ce6588c54a9d227ce6aec45
https://doi.org/10.1021/acs.biochem.1c00126
https://doi.org/10.1021/acs.biochem.1c00126
Publikováno v:
Biophysical Journal. 122:85a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a21541d3d8a0feba7831419fa66d754
https://doi.org/10.1016/j.bpj.2022.11.662
https://doi.org/10.1016/j.bpj.2022.11.662
Autor:
Anne Sofie Busk Heitmann, Jesper Nylandsted, André Vidas Olsen, Catarina Dias, Isabelle da Piedade, Elena Papaleo, Stine Lauritzen Sønder, Swantje Christin Häger
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Häger, S C, Dias, C, Sønder, S L, Olsen, A V, da Piedade, I, Heitmann, A S B, Papaleo, E & Nylandsted, J 2021, ' Short-term transcriptomic response to plasma membrane injury ', Scientific Reports, vol. 11, 19141 . https://doi.org/10.1038/s41598-021-98420-y
Scientific Reports
Häger, S C, Dias, C, Sønder, S L, Olsen, A V, da Piedade, I, Heitmann, A S B, Papaleo, E & Nylandsted, J 2021, ' Short-term transcriptomic response to plasma membrane injury ', Scientific Reports, vol. 11, 19141 . https://doi.org/10.1038/s41598-021-98420-y
Scientific Reports
Plasma membrane repair mechanisms are activated within seconds post-injury to promote rapid membrane resealing in eukaryotic cells and prevent cell death. However, less is known about the regeneration phase that follows and how cells respond to injur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bf17cbfa1acba0a3e5b041cf23a1bbc
https://doi.org/10.1038/s41598-021-98420-y
https://doi.org/10.1038/s41598-021-98420-y
Autor:
Martin Berg Klenow, Jesper Nylandsted, Poul Martin Bendix, Himanshu Khandelia, Anna Mularski, Theresa Louise Boye, Stine Lauritzen Sønder, Adam Cohen Simonsen, Frederik W. Lund, Ali Asghar Hakami Zanjani, Catarina Dias, Anne Sofie Busk Heitmann
Publikováno v:
Heitmann, A S B, Zanjani, A A H, Klenow, M B, Mularski, A, Sønder, S L, Lund, F W, Boye, T L, Dias, C, Bendix, P M, Simonsen, A C, Khandelia, H & Nylandsted, J 2021, ' Phenothiazines alter plasma membrane properties and sensitize cancer cells to injury by inhibiting annexin-mediated repair ', Journal of Biological Chemistry, vol. 297, no. 2, 101012 . https://doi.org/10.1016/j.jbc.2021.101012
The Journal of Biological Chemistry
The Journal of Biological Chemistry
Repair of damaged plasma membrane in eukaryotic cells is largely dependent on the binding of annexin repair proteins to phospholipids. Changing the biophysical properties of the plasma membrane may provide means to compromise annexin-mediated repair
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::762986de24e1d386d2da4f6e961eb250
https://findresearcher.sdu.dk:8443/ws/files/191223600/PIIS0021925821008140.pdf
https://findresearcher.sdu.dk:8443/ws/files/191223600/PIIS0021925821008140.pdf
