Short and long-read ultra-deep sequencing profiles emerging heterogeneity across five platform Escherichia coli strains

Autor: Anne Sofie Brask Dyerberg, Peter Rugbjerg, Christian Munck, Scott Quainoo, Morten Otto Alexander Sommer

Publikováno v: Rugbjerg, P, Dyerberg, A S B, Quainoo, S, Munck, C & Sommer, M O A 2021, ' Short and long-read ultra-deep sequencing profiles emerging heterogeneity across five platform Escherichia coli strains ', Metabolic Engineering, vol. 65, pp. 197-206 . https://doi.org/10.1016/j.ymben.2020.11.006

Reprogramming organisms for large-scale bioproduction counters their evolutionary objectives of fast growth and often leads to mutational collapse of the engineered production pathways during cultivation. Yet, the mutational susceptibility of academi

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https://orbit.dtu.dk/en/publications/4e46de50-d25d-4569-8ae3-95713731a44c