Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Anne Schohl"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract The N-methyl-d-aspartate type glutamate receptor (NMDAR) is a molecular coincidence detector which converts correlated patterns of neuronal activity into cues for the structural and functional refinement of developing circuits in the brain.
Externí odkaz:
https://doaj.org/article/379033e731bd4b3c9cacd71cbb63ef2b
Autor:
Elena Kutsarova, Anne Schohl, Martin Munz, Alex Wang, Yuan Yuan Zhang, Olesia M Bilash, Edward S Ruthazer
Publikováno v:
PLoS Biology, Vol 21, Iss 4, p e3002070 (2023)
During development, patterned neural activity instructs topographic map refinement. Axons with similar patterns of neural activity converge onto target neurons and stabilize their synapses with these postsynaptic partners, restricting exploratory bra
Externí odkaz:
https://doaj.org/article/6d6aaaa6895e4143929ccd17caced66e
Publikováno v:
Cell Reports, Vol 37, Iss 1, Pp 109791- (2021)
Summary: Various types of sensory stimuli have been shown to induce Ca2+ elevations in glia. However, a mechanistic understanding of the signaling pathways mediating sensory-evoked activity in glia in intact animals is still emerging. During early de
Externí odkaz:
https://doaj.org/article/6e545cd321604089b693a19cd5add043
Autor:
Yong Qian, Danielle M Orozco Cosio, Kiryl D Piatkevich, Sarah Aufmkolk, Wan-Chi Su, Orhan T Celiker, Anne Schohl, Mitchell H Murdock, Abhi Aggarwal, Yu-Fen Chang, Paul W Wiseman, Edward S Ruthazer, Edward S Boyden, Robert E Campbell
Publikováno v:
PLoS Biology, Vol 18, Iss 11, p e3000965 (2020)
Near-infrared (NIR) genetically encoded calcium ion (Ca2+) indicators (GECIs) can provide advantages over visible wavelength fluorescent GECIs in terms of reduced phototoxicity, minimal spectral cross talk with visible light excitable optogenetic too
Externí odkaz:
https://doaj.org/article/c61b9ef989474c1c9da003b377045026
Publikováno v:
Frontiers in Neural Circuits, Vol 14 (2020)
Efficient methods for visualizing cell morphology in the intact animal are of great benefit to the study of structural development in the nervous system. Quantitative analysis of the complex arborization patterns of brain cells informs cell-type clas
Externí odkaz:
https://doaj.org/article/bd2c40bdd2324cd4b46f554222f75e1d
Publikováno v:
Cell Reports, Vol 32, Iss 4, Pp 107955- (2020)
Summary: To study contributions of N-methyl-D-aspartate receptors (NMDARs) in presynaptic and postsynaptic neurons of the developing visual system, we microinject antisense Morpholino oligonucleotide (MO) against GluN1 into one cell of two-cell-stage
Externí odkaz:
https://doaj.org/article/bd51f93a3fe444898235283958cd98df
Autor:
Loïs S Miraucourt, Jennifer Tsui, Delphine Gobert, Jean-François Desjardins, Anne Schohl, Mari Sild, Perry Spratt, Annie Castonguay, Yves De Koninck, Nicholas Marsh-Armstrong, Paul W Wiseman, Edward S Ruthazer
Publikováno v:
eLife, Vol 5 (2016)
Type 1 cannabinoid receptors (CB1Rs) are widely expressed in the vertebrate retina, but the role of endocannabinoids in vision is not fully understood. Here, we identified a novel mechanism underlying a CB1R-mediated increase in retinal ganglion cell
Externí odkaz:
https://doaj.org/article/c2fa602935ed4280aa687251b41efb0a
Autor:
Nasr Farooqi, Niklas Brake, Anne Schohl, Edward S. Ruthazer, Philip Kesner, Jack P. Antel, Cynthia M. Solek
Publikováno v:
The Journal of Neuroscience. 41:6353-6366
Neuro-immune interaction during development is strongly implicated in the pathogenesis of neurodevelopmental disorders, but the mechanisms that cause neuronal circuit dysregulation are not well understood. We performed in vivo imaging of the developi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d1879c111c32322c87104ce5b6f2eae
https://doi.org/10.1523/jneurosci.2159-20.2021
https://doi.org/10.1523/jneurosci.2159-20.2021
Autor:
Edward S. Ruthazer, Anne Schohl, Elena Kutsarova, Alex Wang, Yuan Yuan Zhang, Martin Munz, Olesia M. Bilash
Publikováno v:
PLOS Biology. 21:e3002070
During development, patterned neural activity instructs topographic map refinement. Axons with similar patterns of neural activity, converge onto target neurons and stabilize their synapses with these postsynaptic partners, restricting exploratory br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b83454e2d9f7c8051f498b39341279a7
https://doi.org/10.1371/journal.pbio.3002070
https://doi.org/10.1371/journal.pbio.3002070
Publikováno v:
Developmental Neurobiology. 80:332-350
Newly synthesized proteins support the development of functional neural circuits and previous work has suggested that dysregulated translation mediates certain forms of autism spectrum disorder (ASD). Here, we investigated the role of Target of Rapam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fe3a4d72472b8c130f13f26e65deb03
https://doi.org/10.1002/dneu.22782
https://doi.org/10.1002/dneu.22782