Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Anne Schepers"'
Autor:
Marc Terrones, Christophe Deben, Felicia Rodrigues-Fortes, Anne Schepers, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Introduction The study of resistance-causing mutations in oncogene-driven tumors is fundamental to guide clinical decisions. Several point mutations affecting the ROS1 kinase domain have been identified in the clinical setting, but their imp
Externí odkaz:
https://doaj.org/article/8badfa4b346b46089af6735007b9b043
Autor:
Katleen Janssens, Isabelle Neefs, Joe Ibrahim, Anne Schepers, Patrick Pauwels, Marc Peeters, Guy Van Camp, Ken Op de Beeck
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-14 (2023)
Abstract Background Biomarker discovery in colorectal cancer has mostly focused on methylation patterns in normal and colorectal tumor tissue, but adenomas remain understudied. Therefore, we performed the first epigenome-wide study to profile methyla
Externí odkaz:
https://doaj.org/article/f0195dd157dc48ceb7a73e17eb3bb1f3
Autor:
Emilie Logie, Bart Van Puyvelde, Bart Cuypers, Anne Schepers, Herald Berghmans, Jelle Verdonck, Kris Laukens, Lode Godderis, Maarten Dhaenens, Dieter Deforce, Wim Vanden Berghe
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 22, p 12234 (2021)
Disease relapse and therapy resistance remain key challenges in treating multiple myeloma. Underlying (epi-)mutational events can promote myelomagenesis and contribute to multi-drug and apoptosis resistance. Therefore, compounds inducing ferroptosis,
Externí odkaz:
https://doaj.org/article/128c5ee5fc334f36a213008aab24613c
Autor:
Hanne Valgaeren, Vedat Topsakal, Geert Vandeweyer, Alexander Hoischen, Diego Zanetti, Matthias Beyens, Ingeborg Dhooge, Guy Van Camp, Erik Fransen, Isabelle Schatteman, Henricus P. M. Kunst, Alexander M. Huber, Manou Sommen, Isabelle Schrauwen, Anne Schepers
Publikováno v:
Molecular genetics and genomics
Molecular Genetics and Genomics, 294, 1001-1006
Molecular Genetics and Genomics, 294, 4, pp. 1001-1006
Molecular Genetics and Genomics, 294, 1001-1006
Molecular Genetics and Genomics, 294, 4, pp. 1001-1006
Otosclerosis is a common form of hearing loss (HL) due to abnormal remodeling of the otic capsule. The genetic causes of otosclerosis remain largely unidentified. Only mutations in a single gene, SERPINF1, were previously published in patients with f
Autor:
G. Van Camp, K. Op de Beeck, K Biermann, W. W. de Herder, Timon Vandamme, Marc Peeters, Kimberly Kamp, Matthias Beyens, Gitta Boons, Leo J. Hofland, Patrick Pauwels, Anne Schepers
Publikováno v:
Endocrine-related cancer
Endocrine-Related Cancer, 26(1), 1-12. Bioscientifica Ltd
Endocrine-Related Cancer, 26(1), 1-12. Bioscientifica Ltd
Mutations in DAXX/ATRX, MEN1 and genes involved in the phosphoinositide-3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR) pathway have been implicated in pancreatic neuroendocrine neoplasms (pNENs). However, mainly mutations present in the m
Autor:
Dieter Deforce, Herald Berghmans, Anne Schepers, Bart Cuypers, Kris Laukens, Emilie Logie, Maarten Dhaenens, Lode Godderis, Bart Van Puyvelde, Jelle Verdonck, Wim Vanden Berghe
Publikováno v:
International journal of molecular sciences
International Journal of Molecular Sciences
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 22
Issue 22
International Journal of Molecular Sciences, Vol 22, Iss 12234, p 12234 (2021)
International Journal of Molecular Sciences
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 22
Issue 22
International Journal of Molecular Sciences, Vol 22, Iss 12234, p 12234 (2021)
Disease relapse and therapy resistance remain key challenges in treating multiple myeloma. Underlying (epi-)mutational events can promote myelomagenesis and contribute to multi-drug and apoptosis resistance. Therefore, compounds inducing ferroptosis,
Autor:
Alexander M. Huber, Manou Sommen, Anne Schepers, Erik Fransen, Isabelle Schrauwen, Umut Altunoglu, Els De Leenheer, Abdul Nasir, Ronald J.E. Pennings, Mieke Wesdorp, Diego Zanetti, George W. Padberg, Hannie Kremer, Arjan P.M. de Brouwer, Paul Van de Heyning, Matthew J. Huentelman, Berit M. Verbist, Matthias Beyens, Guy Van Camp, Cor W. R. J. Cremers, Hülya Kayserili, Christian Gilissen, Hans van Bokhoven, Hanne Valgaeren, Laura Tomás-Roca, Malika Rahmoun, Geert Vandeweyer, Ingeborg Dhooghe, Ellen van Beusekom, Erwin Offeciers, Alexander Hoischen
Publikováno v:
Genetics in medicine
Genetics in Medicine, 21, 5, pp. 1199-1208
Genetics in Medicine, 21(5), 1199-1208. NATURE PUBLISHING GROUP
Genetics in Medicine, 21, 1199-1208
Genetics in Medicine, 21, 5, pp. 1199-1208
Genetics in Medicine, 21(5), 1199-1208. NATURE PUBLISHING GROUP
Genetics in Medicine, 21, 1199-1208
Purpose To characterize new molecular factors implicated in a hereditary congenital facial paresis (HCFP) family and otosclerosis. Methods We performed exome sequencing in a four-generation family presenting nonprogressive HCFP and mixed hearing loss
Autor:
Katarzyna Szarc vel Szic, Guy Van Camp, Anne Schepers, Patrick De Boever, Sophie Traen, Greet Schoeters, Gudrun Koppen, Wim Vanden Berghe, Sabine A. S. Langie, Ken Declerck
Publikováno v:
ISEE Conference Abstracts. 2014
There is convincing evidence that environmental and lifestyle factors contribute to the development of respiratory allergies (RA), especially if these exposures occur during fetal and early-life de...
Autor:
Anne Schepers, Guy Van Camp, Joris Winderickx, Marina Caldara, Erwin Swinnen, Ken Op de Beeck, Ruben Ghillebert, Vanessa Franssens, Sofie Van Rossom
Publikováno v:
Frontiers in Oncology, Vol 2 (2012)
Frontiers in oncology
Frontiers in Oncology
Frontiers in oncology
Frontiers in Oncology
DFNA5 was first identified as a gene responsible for autosomal dominant deafness. Different mutations were found, but they all resulted in exon 8 skipping during splicing and premature termination of the protein. Later, it became clear that the prote