Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Anne Sadewasser"'
Autor:
Markus Kastner, Andreas Karner, Rong Zhu, Qiang Huang, Andreas Geissner, Anne Sadewasser, Markus Lesch, Xenia Wörmann, Alexander Karlas, Peter H. Seeberger, Thorsten Wolff, Peter Hinterdorfer, Andreas Herrmann, Christian Sieben
Publikováno v:
Viruses, Vol 15, Iss 7, p 1507 (2023)
Influenza A viruses (IAVs) initiate infection via binding of the viral hemagglutinin (HA) to sialylated glycans on host cells. HA’s receptor specificity towards individual glycans is well studied and clearly critical for virus infection, but the co
Externí odkaz:
https://doaj.org/article/1ae2a970a61c4f8eb500c10316c51fb6
Autor:
Mingjuan Deng, Elda Kutrolli, Anne Sadewasser, Sven Michel, Masoumeh Motamedi Joibari, Frank Jaschinski, Gunilla Olivecrona, Stefan K. Nilsson, Sander Kersten
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 7, Pp 100237- (2022)
Angiopoietin-like 4 (ANGPTL4) is an important regulator of plasma triglyceride (TG) levels and an attractive pharmacological target for lowering plasma lipids and reducing cardiovascular risk. Here, we aimed to study the efficacy and safety of silenc
Externí odkaz:
https://doaj.org/article/d5cff7e2f7ae4032a5fb717f4f1072c3
Autor:
Boris Bogdanow, Xi Wang, Katrin Eichelbaum, Anne Sadewasser, Immanuel Husic, Katharina Paki, Matthias Budt, Martha Hergeselle, Barbara Vetter, Jingyi Hou, Wei Chen, Lüder Wiebusch, Irmtraud M. Meyer, Thorsten Wolff, Matthias Selbach
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Avian influenza A virus (IAV) strains replicate poorly in mammalian hosts, but mechanisms underlying species restriction are incompletely understood. Here, Bogdanow et al. show that avian and mammalian adapted IAV strains have evolved different RNA s
Externí odkaz:
https://doaj.org/article/31c5226fb8bf4e6b9bc945e1829498fd
Autor:
Anne Sadewasser, Erik Dietzel, Sven Michel, Michael Klüver, Markus Helfer, Tamara Thelemann, Richard Klar, Markus Eickmann, Stephan Becker, Frank Jaschinski
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 16, Iss , Pp 686-697 (2019)
Ebola virus is the causative agent of Ebola virus disease, a severe, often fatal illness in humans. So far, there are no US Food and Drug Administration (FDA)-approved therapeutics directed against Ebola virus. Here, we selected the host factor Niema
Externí odkaz:
https://doaj.org/article/308c7be2e7a44d74b79da85945b8925c
Autor:
Rocío Daviña Núñez, Matthias Budt, Sandra Saenger, Katharina Paki, Ulrike Arnold, Anne Sadewasser, Thorsten Wolff
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 7, p 1877 (2018)
Virus infections induce sensitive antiviral responses within the host cell. The RNA helicase retinoic acid-inducible gene I (RIG-I) is a key sensor of influenza virus RNA that induces the expression of antiviral type I interferons. Recent evidence su
Externí odkaz:
https://doaj.org/article/55f840af451f469baea794c97130fc76
Autor:
Markus Eickmann, Anne Sadewasser, Tamara Thelemann, Frank Jaschinski, Sven Michel, Michael Klüver, Erik Dietzel, Stephan Becker, Richard Klar, Markus Helfer
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 16, Iss, Pp 686-697 (2019)
Molecular Therapy: Nucleic Acids, Vol 16, Iss, Pp 686-697 (2019)
Ebola virus is the causative agent of Ebola virus disease, a severe, often fatal illness in humans. So far, there are no US Food and Drug Administration (FDA)-approved therapeutics directed against Ebola virus. Here, we selected the host factor Niema
Publikováno v:
Journal of General Virology. 97:2856-2867
The influenza virus non-structural protein 1 (NS1) is a multifunctional virulence factor that plays a crucial role during infection by blocking the innate antiviral immune response of infected cells. In contrast to the well-studied NS1 protein of inf
Autor:
Nan Zhang, Styliani Taka, B. Alashkar Alhamwe, Chrysanthi Skevaki, Spyridon Megremis, Stephan Becker, Sebastian D. Unger, Nikolaos G. Papadopoulos, M. Akdis, Michael R. Edwards, Daniel P. Potaczek, Markus Eickmann, Anne Sadewasser, Feng Lan, Markus Helfer, Sven Michel, Cezmi A. Akdis, Claus Bachert, Holger Garn, Harald Renz, Christoph Hudemann, Nesibe Akdag, Fahd Alhamdan, Sebastian L. Johnston
Publikováno v:
B33. ASTHMA: MECHANISMS OF DISEASE II.
Autor:
Michael R. Edwards, Markus Eickmann, Anne Sadewasser, Bilal Alashkar Alhamwe, Sebastian L. Johnston, Nikolaos G. Papadopoulos, Stephan Becker, Nan Zhang, Styliani Taka, Markus Helfer, Sven Michel, Spyridon Megremis, Sebastian D. Unger, Cezmi A. Akdis, Claus Bachert, Daniel P. Potaczek, Fahd Alhamdan, Holger Garn, Nesibe Akdag, Mübeccel Akdis, Christoph Hudemann, Feng Lan, Chrysanthi Skevaki, Harald Renz
Publikováno v:
Potaczek, D P, Unger, S D, Zhang, N, Taka, S, Michel, S, Akdağ, N, Lan, F, Helfer, M, Hudemann, C, Eickmann, M, Skevaki, C, Megremis, S, Sadewasser, A, Alashkar Alhamwe, B, Alhamdan, F, Akdis, M, Edwards, M R, Johnston, S L, Akdis, C A, Becker, S, Bachert, C, Papadopoulos, N G, Garn, H & Renz, H 2019, ' Development and characterization of DNAzyme candidates demonstrating significant efficiency against human rhinoviruses ', Journal of Allergy and Clinical Immunology, vol. 143, no. 4, pp. 1403-1415 . https://doi.org/10.1016/j.jaci.2018.07.026, https://doi.org/10.1016/j.jaci.2018.07.026
BACKGROUND: Infections with human rhinoviruses (RVs) are responsible for millions of common cold episodes and the majority of asthma exacerbations, especially in childhood. No drugs specifically targeting RVs are available.OBJECTIVE: We sought to ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e541982fd313122949588ef1785f6c3c
https://doi.org/10.1016/j.jaci.2018.07.026
https://doi.org/10.1016/j.jaci.2018.07.026
Autor:
Xi Wang, Boris Bogdanow, Katrin Eichelbaum, Anne Sadewasser, Lueder Wiebusch, Wei Chen, Thorsten Wolff, Martha Hergeselle, Immanuel Husic, Irmtraud M. Meyer, Katharina Paki, Jingyi Hou, Barbara Vetter, Matthias Selbach
SUMMARYA century ago, influenza A virus (IAV) infection caused the 1918 flu pandemic and killed an estimated 20-40 million people. Pandemic IAV outbreaks occur when strains from animal reservoirs acquire the ability to infect and spread among humans.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9476124cee7880617c92e121a3311872
https://doi.org/10.1101/438176
https://doi.org/10.1101/438176