Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Anne S. Robinson"'
Publikováno v:
Biomedicines, Vol 8, Iss 12, p 603 (2020)
Recent efforts to determine the high-resolution crystal structures for the adenosine receptors (A1R and A2AR) have utilized modifications to the native receptors in order to facilitate receptor crystallization and structure determination. One common
Externí odkaz:
https://doaj.org/article/e0c81720420346868720279e94a2c1cb
Publikováno v:
Antibodies, Vol 7, Iss 1, p 1 (2017)
In order to meet desired drug product quality targets, the glycosylation profile of biotherapeutics such as monoclonal antibodies (mAbs) must be maintained consistently during manufacturing. Achieving consistent glycan distribution profiles requires
Externí odkaz:
https://doaj.org/article/9d23206bae0a4559b3e4140477a89929
Publikováno v:
Biotechnology Progress.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f329008468937c68a5b7d15a93c57e49
https://doi.org/10.1002/btpr.3365
https://doi.org/10.1002/btpr.3365
Publikováno v:
Trends in Biotechnology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe6fad900d3e739dd75601a7961de744
https://doi.org/10.1016/j.tibtech.2023.02.006
https://doi.org/10.1016/j.tibtech.2023.02.006
Autor:
Claire McGraw, Steven H. Stradley, Kirsten S. Koretz, Anne S. Robinson, Noah Malmstadt, Ahmed Elbaradei
Publikováno v:
Biophysical Journal. 120:1641-1649
Because of their surface localization, G protein-coupled receptors (GPCRs) are often pharmaceutical targets as they respond to a variety of extracellular stimuli (e.g., light, hormones, small molecules) that may activate or inhibit a downstream signa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9f2968c778a4dc6e99eb9167b9fae17
https://doi.org/10.1016/j.bpj.2021.02.032
https://doi.org/10.1016/j.bpj.2021.02.032
Publikováno v:
Biophysical Journal. 122:15a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05c7a1f297bb7a6a5f4028a6df6f9ee9
https://doi.org/10.1016/j.bpj.2022.11.310
https://doi.org/10.1016/j.bpj.2022.11.310
The conversion of soluble tau protein to insoluble, hyperphosphorylated neurofibrillary tangles is a major hallmark leading to neuronal death observed in neurodegenerative tauopathies. Recent work suggests that extracellular, soluble tau binds to neg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::237da0e4c67baf6e288086c8a0c4127f
https://doi.org/10.21203/rs.3.rs-647000/v1
https://doi.org/10.21203/rs.3.rs-647000/v1
Publikováno v:
Journal of Molecular Neuroscience
The conversion of soluble tau protein to insoluble, hyperphosphorylated neurofibrillary tangles (NFTs) is a major hallmark leading to neuronal death observed in neurodegenerative tauopathies. Unlike NFTs, the involvement of monomeric tau in the progr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64762dd90a49ddb70f1b811c496a6dfe
https://pubmed.ncbi.nlm.nih.gov/35040015
https://pubmed.ncbi.nlm.nih.gov/35040015
Publikováno v:
Current Opinion in Chemical Engineering. 22:81-88
The production of commercially valuable biotherapeutic molecules in mammalian systems has expanded significantly in the last thirty years, but growing economic pressures within the industry are driving efforts to reduce costs and enhance process yiel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3703e080ad39bf8bc541124a2b30a78b
https://doi.org/10.1016/j.coche.2018.09.005
https://doi.org/10.1016/j.coche.2018.09.005
Publikováno v:
Biomedicines
Biomedicines, Vol 9, Iss 190, p 190 (2021)
Biomedicines, Vol 9, Iss 190, p 190 (2021)
Tauopathies represent a group of neurodegenerative diseases including Alzheimer’s disease (AD) that are characterized by the deposition of filamentous tau aggregates in the brain. The pathogenesis of tauopathies starts from the formation of toxic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d55d72ce30d14c7f0a36bed62f5b67b
http://europepmc.org/articles/PMC7918468
http://europepmc.org/articles/PMC7918468