Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Anne S. Calkins"'
Autor:
Matija Dreze, Anne S Calkins, Judit Gálicza, Daniel J Echelman, Mathew R Schnorenberg, Gillian L Fell, Shigenori Iwai, David E Fisher, David Szüts, J Dirk Iglehart, Jean-Bernard Lazaro
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85896 (2014)
Because cells are constantly subjected to DNA damaging insults, DNA repair pathways are critical for genome integrity [1]. DNA damage recognition protein complexes (DRCs) recognize DNA damage and initiate DNA repair. The DNA-Damage Binding protein 2
Externí odkaz:
https://doaj.org/article/75b1ffd2a6a74e609d2a41653e46bd91
Publikováno v:
Nucleic Acids Research
RNA synthesis and DNA replication cease after DNA damage. We studied RNA synthesis using an in situ run-on assay and found ribosomal RNA (rRNA) synthesis was inhibited 24 h after UV light, gamma radiation or DNA cross-linking by cisplatin in human ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::839e87234b1163de465050e1e32f35dc
https://doi.org/10.1093/nar/gkt502
https://doi.org/10.1093/nar/gkt502
Autor:
Guillaume Adelmant, Jarrod A. Marto, Bijan Sobhian, Pamela A. Silver, Brijesh K. Garg, Jean Bernard Lazaro, Yi Zhang, Anne S. Calkins, Yoshihiro Nakatani, Alex Miron, Manor Askenazi, Joseph D. Card, J. Dirk Iglehart
Publikováno v:
Molecular & Cellular Proteomics. 11:411-421
The Ku heterodimer plays an essential role in non-homologous end-joining and other cellular processes including transcription, telomere maintenance and apoptosis. While the function of Ku is regulated through its association with other proteins and n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a69b5aee6df4dfb51f4dcec99fbdbb94
https://doi.org/10.1074/mcp.m111.013581
https://doi.org/10.1074/mcp.m111.013581
Autor:
Anne S. Calkins, Matija Dreze, Dávid Szüts, Shigenori Iwai, Gillian L. Fell, Mathew R. Schnorenberg, David E. Fisher, Daniel J. Echelman, Judit Gálicza, J. Dirk Iglehart, Jean Bernard Lazaro
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 1, p e85896 (2014)
PLoS ONE, Vol 9, Iss 1, p e85896 (2014)
Because cells are constantly subjected to DNA damaging insults, DNA repair pathways are critical for genome integrity [1]. DNA damage recognition protein complexes (DRCs) recognize DNA damage and initiate DNA repair. The DNA-Damage Binding protein 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3621a3b13312ce385744f8893c21bca
https://pubmed.ncbi.nlm.nih.gov/24489677
https://pubmed.ncbi.nlm.nih.gov/24489677
Autor:
Anne S. Calkins, Mehmet Kemal Samur, Kenneth C. Anderson, Raphael Szalat, Hervé Avet-Loiseau, Matija Dreze, Jean-Bernard Lazaro, Jean-Paul Fermand, Nikhil C. Munshi, Yu-Tzu Tai, Stephane Minvielle, Alice Cleynen
Publikováno v:
Blood. 126:4187-4187
Nucleotide excision repair (NER) is involved in the removal of bulky adducts and DNA crosslinks induced by various genotoxins including alkylating agents. In cancer, somatic mutations, genes' up-regulation, and epigenetic silencing of NER may lead to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99007a42a3e1f6f584adcb3f7ceab8e7
https://doi.org/10.1182/blood.v126.23.4187.4187
https://doi.org/10.1182/blood.v126.23.4187.4187
Autor:
Jean-Bernard Lazaro, Janna Sand-Dejmek, Bijan Sobhian, Jarrod A. Marto, Anne S. Calkins, Dirk Iglehart, Guillaume Adelmant
Publikováno v:
Molecular Cancer
Molecular Cancer, Vol 10, Iss 1, p 74 (2011)
Molecular Cancer, Vol 10, Iss 1, p 74 (2011)
Background Platinum-containing chemotherapy produces specific DNA damage and is used to treat several human solid tumors. Tumors initially sensitive to platinum-based drugs frequently become resistant. Inhibition of DNA repair is a potential strategy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b270ae8093b7b10a3e529dd7460acc58
https://doi.org/10.1186/1476-4598-10-74
https://doi.org/10.1186/1476-4598-10-74
Autor:
Anne S. Calkins, M Dreze, JD Iglehart, J-B Lazaro, Schnorenberg, David E. Fisher, GL Fell, DJ Echelman
Publikováno v:
Cancer Research. 73:P3-04
The response of tumor cells to DNA damaging agents is often compromised, a weakness readily exploited for therapeutic purposes. Despite the general use of genotoxic treatments, the nature and extent of DNA damage in tumor cells is generally under-inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73124b0a1fde973c50d000e997ce62b0
https://doi.org/10.1158/0008-5472.sabcs13-p3-04-08
https://doi.org/10.1158/0008-5472.sabcs13-p3-04-08
Autor:
Matija Dreze, J. Dirk Iglehart, Raphael Ceccaldi, Anne S. Calkins, Mathew R. Schnorenberg, Raphael Szalat, Jean-Bernard Lazaro
Publikováno v:
Journal of Clinical Oncology. 33:1077-1077
1077 Background: Nucleotide excision repair (NER) of DNA is necessary for removal of crosslinks and other damage produced by UV light, genotoxins and chemotherapies. Germline NER deficiency causes ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::833395d27730815fc51dd629ab76df98
https://doi.org/10.1200/jco.2015.33.15_suppl.1077
https://doi.org/10.1200/jco.2015.33.15_suppl.1077
Nucleotide Excision Repair (NER) Is Frequently Impaired and Affects Outcome in Multiple Myeloma (MM)
Autor:
Mehmet Kemal Samur, Raphael Szalat, Hervé Avet-Loiseau, Kenneth C. Anderson, Matija Dreze, Jean-Bernard Lazaro, Giovanni Parmigiani, Anne S. Calkins, Nikhil C. Munshi, Jean-Paul Fermand
Publikováno v:
Blood. 124:2055-2055
Introduction Multiple Myeloma (MM) is a heterogeneous disease characterized by genomic instability and eventual poor outcome. Aberrations in DNA repair-related pathways have been considered to explain the instability. Nucleotide excision repair (NER)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::511ca9ae81fdf7ad2f439027c644ef13
https://doi.org/10.1182/blood.v124.21.2055.2055
https://doi.org/10.1182/blood.v124.21.2055.2055