Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Anne Rupprecht"'
Autor:
Christin Riess, Katharina del Moral, Adina Fiebig, Philipp Kaps, Charlotte Linke, Burkhard Hinz, Anne Rupprecht, Marcus Frank, Tomas Fiedler, Dirk Koczan, Sascha Troschke-Meurer, Holger N. Lode, Nadja Engel, Thomas Freitag, Carl Friedrich Classen, Claudia Maletzki
Publikováno v:
Cell Death and Disease, Vol 13, Iss 6, Pp 1-14 (2022)
The complex effects of combined CDki/SPyADI application on arginine-auxotrophic glioblastoma multiforme cells. CDki/SPyADI combination therapy impairs cell proliferation, invasiveness, gene expression, induces mitochondrial impairment, and vacuole fo
Externí odkaz:
https://doaj.org/article/e4a237d57e9d4704bd9c0f69a431ba27
Autor:
Franziska Wendt, Felix Wittig, Anne Rupprecht, Robert Ramer, Peter Langer, Steffen Emmert, Marcus Frank, Burkhard Hinz
Publikováno v:
Cells, Vol 12, Iss 19, p 2409 (2023)
Skin cancer is the most common malignant disease worldwide and, therefore, also poses a challenge from a pharmacotherapeutic perspective. Derivatives of indirubin are an interesting option in this context. In the present study, the effects of 3-[3′
Externí odkaz:
https://doaj.org/article/e4d653d7f8ce482784066c1f5d33ff3b
Autor:
Michael Moschinger, Karolina E. Hilse, Anne Rupprecht, Ute Zeitz, Reinhold G. Erben, Thomas Rülicke, Elena E. Pohl
Publikováno v:
Biology of Sex Differences, Vol 10, Iss 1, Pp 1-10 (2019)
Abstract The prevalence and progression of many illnesses, such as neurodegenerative and cardiovascular diseases, obesity, and cancer, vary between women and men, often in an age-dependent manner. A joint hallmark of these diseases is some type of mi
Externí odkaz:
https://doaj.org/article/35c1374042454c87a4079c1d5b107eea
Autor:
Doris Kaltenecker, Katrin Spirk, Frank Ruge, Florian Grebien, Marco Herling, Anne Rupprecht, Lukas Kenner, Elena E. Pohl, Kristina M. Mueller, Richard Moriggl
Publikováno v:
Molecular Metabolism, Vol 40, Iss , Pp 101026- (2020)
Objective: Increasing energy expenditure through activation of brown adipose tissue (BAT) thermogenesis is an attractive approach to counteract obesity. It is therefore essential to understand the molecular mechanisms that control BAT functions. Unti
Externí odkaz:
https://doaj.org/article/f475183fc9204449837848d6d6031f90
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Membrane uncoupling protein 3 (UCP3), a member of the mitochondrial uncoupling protein family, was discovered in 1997. UCP3′s properties, such as its high homology to other mitochondrial carriers, especially to UCP2, its short lifetime and low spec
Externí odkaz:
https://doaj.org/article/8a5dc88c45d243ff8dacced5dd514b54
Autor:
Jürgen Kreiter, Anne Rupprecht, Sanja Škulj, Zlatko Brkljača, Kristina Žuna, Denis G. Knyazev, Sarah Bardakji, Mario Vazdar, Elena E. Pohl
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5, p 2490 (2021)
Adenine nucleotide translocase (ANT) is a well-known mitochondrial exchanger of ATP against ADP. In contrast, few studies have shown that ANT also mediates proton transport across the inner mitochondrial membrane. The results of these studies are con
Externí odkaz:
https://doaj.org/article/7f5aa2b59eb94367aef99742c938413e
Autor:
Karolina E. Hilse, Anne Rupprecht, Monika Egerbacher, Sarah Bardakji, Lars Zimmermann, Andrea E. M. Seiler Wulczyn, Elena E. Pohl
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
The involvement of mitochondrial uncoupling proteins 2 and 3 in the pathogenesis of cardiovascular diseases is widely acknowledged. However, contradictory reports show that the functions of UCP2/UCP3 are still disputed. We have previously described t
Externí odkaz:
https://doaj.org/article/fcd3117471464676be3d98981d4c03a8
Autor:
Anne Rupprecht, Dana Sittner, Alina Smorodchenko, Karolina E Hilse, Justus Goyn, Rudolf Moldzio, Andrea E M Seiler, Anja U Bräuer, Elena E Pohl
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88474 (2014)
Apart from the first family member, uncoupling protein 1 (UCP1), the functions of other UCPs (UCP2-UCP5) are still unknown. In analyzing our own results and those previously published by others, we have assumed that UCP's cellular expression pattern
Externí odkaz:
https://doaj.org/article/2cc7e5101ac945e5933c7ab41eba3e5c
Autor:
Elena A Malingriaux, Anne Rupprecht, Lars Gille, Olga Jovanovic, Petr Jezek, Martin Jaburek, Elena E Pohl
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77786 (2013)
The production of reactive oxygen species (ROS) in mitochondria is very sensitive to the proton motive force and may be decreased by mild uncoupling, mediated e.g. by mitochondrial uncoupling proteins (UCPs). UCPs were conversely hypothesized to be a
Externí odkaz:
https://doaj.org/article/73c5601a52bc489dafef0f5e07e71a33
Autor:
Anne Rupprecht, Anja U Bräuer, Alina Smorodchenko, Justus Goyn, Karolina E Hilse, Irina G Shabalina, Carmen Infante-Duarte, Elena E Pohl
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e41406 (2012)
Uncoupling protein 2 (UCP2) is an inner mitochondrial membrane protein. Although the protein was discovered in 1997, its function and even its tissue distribution are still under debate. Here we present a quantitative analysis of mRNA and protein exp
Externí odkaz:
https://doaj.org/article/244f9c58fc104505a2261f1df08d6914