Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Anne Routledge"'
Autor:
Chidi Amadi‐Kamalu, Holly Clarke, Matthew McRobie, James Mortimer, Prof. Michael North, Yanrui Ran, Dr. Anne Routledge, Dani Sibbald, Matthew Tickias, Kai Tse, Helen Willway
Publikováno v:
ChemistryOpen, Vol 9, Iss 4, Pp 431-441 (2020)
Abstract The influence of various physical and chemical factors on the swelling of polystyrene and PEG based resins in greener organic solvents has been systematically investigated. In general, chemical factors: the nature of the functionality/linker
Externí odkaz:
https://doaj.org/article/b1b9f64cfe5a4577b987c70e5f0664ef
Publikováno v:
Journal of inorganic biochemistry. 234
A novel Trojan Horse conjugate consisting of an SO
Autor:
Eszter Boros, Ellis J. Wilde, Anne Routledge, Conor M. Black, Anne-Kathrin Duhme-Klair, Apurva Pandey, James W. Southwell, Reyme Herman, Gavin H. Thomas, Thomas J. Sanderson
A novel ciprofloxacin-siderophore Trojan Horse antimicrobial was prepared by incorporating key design features of salmochelin S4, a stealth siderophore that evades mammalian siderocalin capture via its glycosylated catechol units. As-sessment of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72fb5caca9fe56330a2161a740d53d39
https://eprints.whiterose.ac.uk/164830/8/acsinfecdis.0c00568.pdf
https://eprints.whiterose.ac.uk/164830/8/acsinfecdis.0c00568.pdf
Autor:
Yanrui Ran, Helen Willway, Holly Clarke, James Mortimer, Kai Tse, Matthew McRobie, Michael North, Chidi Amadi-Kamalu, Matthew Tickias, Dani Sibbald, Anne Routledge
Publikováno v:
ChemistryOpen
ChemistryOpen, Vol 9, Iss 4, Pp 431-441 (2020)
ChemistryOpen, Vol 9, Iss 4, Pp 431-441 (2020)
The influence of various physical and chemical factors on the swelling of polystyrene and PEG based resins in greener organic solvents has been systematically investigated. In general, chemical factors: the nature of the functionality/linker and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6bbe4ccf48628923a33033e549756ec
https://eprints.whiterose.ac.uk/159310/1/open.202000030.pdf
https://eprints.whiterose.ac.uk/159310/1/open.202000030.pdf
Autor:
Ursula Bilitewski, Anne-Kathrin Duhme-Klair, Sabine Laschat, Joshua A. V. Blodgett, Anne Routledge, Sabrina Dallavalle, Rainer Schobert
Publikováno v:
Angewandte Chemie. 129:14552-14575
Eine der Verteidigungsstrategien eines Wirtes gegen bakterielle Infektionen ist der Entzug essentieller Metallionen, insbesondere von Eisenionen, durch Komplexierung. Dies wird als Nahrstoffimmunitat (“nutritional immunity”) bezeichnet. Bakterien
Autor:
Keith S. Wilson, Anne-Kathrin Duhme-Klair, Thomas J. Sanderson, Ellis J. Wilde, Anne Routledge, Elena Blagova, Ross P. Thomas, Daniel J. Raines
A mimic of the tetradentate stealth siderophore salmochelin S1, was synthesised, characterised and shown to form Fe(III) complexes with ligand-to-metal ratios of 1:1 and 3:2. Circular dichroism spectroscopy confirmed that the periplasmic binding prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4104165926e68d0c85155bb9e188341
https://eprints.whiterose.ac.uk/137417/1/E_Wilde_author_accepted_manuscript.pdf
https://eprints.whiterose.ac.uk/137417/1/E_Wilde_author_accepted_manuscript.pdf
The use of a variety of green solvents to swell a diverse range of resins used in solid-phase synthesis is investigated. Good swelling is shown to depend on the structure of the resin and the solvent. A modelling approach based on use of a training s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f34d1bdac81d5ff40455e5543bc1906
https://eprints.whiterose.ac.uk/115811/1/c6gc03147a.pdf
https://eprints.whiterose.ac.uk/115811/1/c6gc03147a.pdf
Autor:
Anne Routledge, Anne-Kathrin Duhme-Klair, Sabine Laschat, Joshua A. V. Blodgett, Sabrina Dallavalle, Rainer Schobert, Ursula Bilitewski
Publikováno v:
Angewandte Chemie (International ed. in English). 56(46)
Upon bacterial infection, one of the defense mechanisms of the host is the withdrawal of essential metal ions, in particular iron, which leads to "nutritional immunity". However, bacteria have evolved strategies to overcome iron starvation, for examp
Autor:
Anne-Kathrin Duhme-Klair, Anna M. Snelling, Roderick E. Hubbard, Gavin H. Thomas, Anne Routledge, Kevin G. Kerr, Ahmad Abd-El-Aziz, Stephen J. Milner
Publikováno v:
Bioorganic & Medicinal Chemistry. 22:4499-4505
A series of structurally related citric acid–ciprofloxacin conjugates was synthesised to investigate the influence of the linker between citric acid and ciprofloxacin on antibacterial activities. Minimum inhibitory concentrations (MICs) were determ
Autor:
Siân R. Hudson, Roberto Castangia, Sabine L. Flitsch, Helen K. Robinson, Jane Thomas-Oates, Anne Routledge
Publikováno v:
Castangia, R, Hudson, S R, Robinson, H K, Flitsch, S, Thomas-Oates, J & Routledge, A 2016, ' Fabrication and Application of Isotopically-Labelled Gold Arrays for Multiplexed Peptide Analysis ', CHEMBIOCHEM, vol. 17, no. 21 . https://doi.org/10.1002/cbic.201600347
A new array-based technology for the simultaneous capture, chemical labelling and mass spectrometry analysis of peptides is presented. Isotopically labelled self-assembled monolayer (SAM) gold arrays are constructed and used simultaneously to capture