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Autor:
Anne Raisanen-Sokolwski, Suzanne E. Connaughton, Mark A. Labow, Abhay R. Satoskar, Mitsuhiro Okano, John R. David
Publikováno v:
European Journal of Immunology. 28:2066-2074
IL-1 has a number of effects on T cell growth but a specific role for IL-1 in T cell responses in vivo has not been elucidated. In this study the role of IL-1 in Th1/Th2 responses was examined in mice deficient for the IL-1 type 1 receptor (IL-1RI-/-