Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Anne R. Greenlee"'
Autor:
Anne R Greenlee, Meng-Shin Shiao, Elizabeth Snyder, F William Buaas, Tongjun Gu, Timothy M Stearns, Manju Sharma, Elizabeth P Murchison, Gabriella C Puente, Robert E Braun
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46359 (2012)
MicroRNAs (miRNAs) are a class of endogenous, non-coding RNAs that mediate post-transcriptional gene silencing by inhibiting mRNA translation and promoting mRNA decay. DICER1, an RNase III endonuclease encoded by Dicer1, is required for processing sh
Externí odkaz:
https://doaj.org/article/4d91b14f715944f5ba42139b4d96e81d
Publikováno v:
Biology of Reproduction. 85:254-260
In the mammalian testis, meiotic and postmeiotic germ cell antigens are granted immune privilege. Both local immune suppression and specialized intercellular junctions between somatic Sertoli cells have been proposed to contribute to a highly restric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba408314ae0e4c3269d2e278ca8bb98e
https://doi.org/10.1095/biolreprod.110.090621
https://doi.org/10.1095/biolreprod.110.090621
Publikováno v:
Carcinogenesis. 32:713-722
Gastric cancer is the fourth most common cancer and the second leading cause of cancer mortality worldwide but the underlying molecular mechanism is not entirely clear. The objective of this study was to explore the role of let-7a microRNA (miRNA) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ee088efe6d2c42c3a17ea0adf3f6027
https://doi.org/10.1093/carcin/bgr035
https://doi.org/10.1093/carcin/bgr035
Publikováno v:
Toxicological Sciences. 119:50-60
microRNAs (miRNAs) are an abundant class of small noncoding RNAs that function primarily as oncogenes and tumor suppressors by mediating translational repression or mRNA degradation via binding target genes. In this study, malignant human bronchial e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7c7e43c870261c9467cb6e9cf5a0067
https://doi.org/10.1093/toxsci/kfq306
https://doi.org/10.1093/toxsci/kfq306
Publikováno v:
Biomedical and Environmental Sciences. 22:14-21
Objective To screen miRNA profiles of malignantly transformed human bronchial epithelial cells, 16HBE-T, induced by anti-benzo[a]pyrene-trans-7,8-diol-9,10-epoxide (anti-BPDE), and to analyze putative miR-10a targets in 16HBE-T. Methods A novel micro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8298ac1e0ae729d58cf4ea2c271a94bf
https://doi.org/10.1016/s0895-3988(09)60016-7
https://doi.org/10.1016/s0895-3988(09)60016-7
Publikováno v:
Toxicology in Vitro. 23:53-59
Anti-benzo[a]pyrene-7,8-diol-9,10-epoxide (anti-BPDE) is a metabolite of benzo[a]pyrene (B[a]P) and acts as a potent mutagen in mammalian systems. However, the molecular mechanisms related to anti-BPDE-induced carcinogenesis are poorly understood. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7e16c170ebe33405b37db1e3f52eb3d
https://doi.org/10.1016/j.tiv.2008.10.002
https://doi.org/10.1016/j.tiv.2008.10.002
Autor:
Anne R. Greenlee, Qiaoyuan Yang, Aijun Tan, Yiguo Jiang, Yuelan Shen, Linhua Liu, Lanlan Zhou
Publikováno v:
Toxicological Sciences. 105:286-294
Anti-benzo[a]pyrene-trans-7,8-diol-9,10-epoxide (anti-BPDE) is the most important metabolite of benzo[a]pyrene which is a ubiquitous environmental pollutant, and may cause human cancer, especially of the lung. Ras genes (H, K, and N) are activated in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79762c56aede2b5f9a164004f189802a
https://doi.org/10.1093/toxsci/kfn122
https://doi.org/10.1093/toxsci/kfn122
Publikováno v:
Toxicology in Vitro. 22:515-524
The objective of this in vitro study was to use a mouse embryonic stem (mES) cell model to better understand pesticide injury that may adversely affect early pregnancy and to evaluate an antioxidant intervention. Undifferentiated D3 mES cells were in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cdbfd68e89e6c2eba0c3fe481564fc2
https://doi.org/10.1016/j.tiv.2007.11.008
https://doi.org/10.1016/j.tiv.2007.11.008
Publikováno v:
Reproductive Toxicology. 20:229-238
Pregnancy outcomes were evaluated following uterine transfer of murine preimplantation embryos exposed in vitro to the estrogenic pesticide o , p ′-dichlorodiphenyltrichloroethane ( o , p ′-DDT). Single-cell embryos were incubated 72 h in medium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d25a2edc6544b74099a0b02123e09c23
https://doi.org/10.1016/j.reprotox.2005.02.004
https://doi.org/10.1016/j.reprotox.2005.02.004
Publikováno v:
Environmental Health Perspectives
Occupational exposures to pesticides may increase parental risk of infertility and adverse pregnancy outcomes such as spontaneous abortion, preterm delivery, and congenital anomalies. Less is known about residential use of pesticides and the risks th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::449882e92a220cfc0924da440250a7ad
https://doi.org/10.1289/ehp.6774
https://doi.org/10.1289/ehp.6774