Enhanced Pathogenesis Caused by Influenza D Virus and Mycoplasma bovis Coinfection in Calves: a Disease Severity Linked with Overexpression of IFN-γ as a Key Player of the Enhanced Innate Immune Response in Lungs

Autor: Adrien Lion, Aurélie Secula, Camille Rançon, Olivier Boulesteix, Anne Pinard, Alain Deslis, Sara Hägglund, Elias Salem, Hervé Cassard, Katarina Näslund, Maria Gaudino, Ana Moreno, Emiliana Brocchi, Maxence Delverdier, Siamak Zohari, Eric Baranowski, Jean-François Valarcher, Mariette F. Ducatez, Gilles Meyer

Publikováno v: Microbiology Spectrum, Vol 9, Iss 3 (2021)

ABSTRACT Bovine respiratory disease (BRD) is a major disease of young cattle whose etiology lies in complex interactions between pathogens and environmental and host factors. Despite a high frequency of codetection of respiratory pathogens in BRD, da

Externí odkaz: https://doaj.org/article/e60eff23050246cd859e469b993099f3

Establishment of a Newborn Lamb Gut-Loop Model to Evaluate New Methods of Enteric Disease Control and Reduce Experimental Animal Use

Autor: Ambre Baillou, Nathalie Kasal-Hoc, Céline Barc, Juliette Cognié, Anne Pinard, Jérémy Pezant, Julie Schulthess, Pauline Peltier-Pain, Sonia Lacroix-Lamandé, Fabrice Laurent

Publikováno v: Veterinary Sciences, Vol 8, Iss 9, p 170 (2021)

Enteric infectious diseases are not all well controlled, which leads to animal suffering and sometimes death in the most severe cases, in addition to economic losses for farmers. Typical symptoms of enteric infections include watery diarrhea, stomach

Externí odkaz: https://doaj.org/article/733d9beb8f3f43fb8ccbe448872f178d

Single-Shot Vaccines against Bovine Respiratory Syncytial Virus (BRSV): Comparative Evaluation of Long-Term Protection after Immunization in the Presence of BRSV-Specific Maternal Antibodies

Autor: Jean François Valarcher, Sara Hägglund, Katarina Näslund, Luc Jouneau, Ester Malmström, Olivier Boulesteix, Anne Pinard, Dany Leguéré, Alain Deslis, David Gauthier, Catherine Dubuquoy, Vincent Pietralunga, Aude Rémot, Alexander Falk, Ganna Shevchenko, Sara Bergström Lind, Claudia Von Brömssen, Karin Vargmar, Baoshan Zhang, Peter D. Kwong, María Jose Rodriguez, Marga Garcia Duran, Isabelle Schwartz-Cornil, Geraldine Taylor, Sabine Riffault

Publikováno v: Vaccines, Vol 9, Iss 3, p 236 (2021)

The induction of long-lasting clinical and virological protection is needed for a successful vaccination program against the bovine respiratory syncytial virus (BRSV). In this study, calves with BRSV-specific maternally derived antibodies were vaccin

Externí odkaz: https://doaj.org/article/14e8581d0527445b8ffbe4eb17e80d8b

In Vivo Tracking of Bacterial Colonization in Different Murine Models Using Bioluminescence: The Example of Salmonella

Autor: Michaël, Koczerka, Isabelle, Lantier, Anne, Pinard, Marie, Morillon, Justine, Deperne, Ohad, Gal-Mor, Olivier, Grépinet, Isabelle, Virlogeux-Payant

Publikováno v: Methods in molecular biology (Clifton, N.J.). 2427

Applications of bioluminescence for the in vivo study of pathogenic microorganisms are numerous, ranging from the quantification of virulence gene expression to measuring the effect of antimicrobial molecules on the colonization of tissues and organs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::639a9828af9b95b2cb0b2e9cd448aefd
https://pubmed.ncbi.nlm.nih.gov/35619038

Tetrafunctional Block Copolymers Promote Lung Gene Transfer in Newborn Piglets

Autor: Océane Hacquin, Jérémy Pezant, Anne Pinard, Bruno Pitard, Claire Chevaleyre, Julien Fassy, Céline Barc, Mickaël Riou, Georges Vassaux, Roger Rezzonico, Bernard Mari, Ignacio S. Caballero, Nathalie Heuzé-Vourc'h

Publikováno v: Molecular Therapy-Nucleic Acids
Molecular Therapy-Nucleic Acids, Elsevier, 2019, 16, pp.186-193. ⟨10.1016/j.omtn.2019.02.016⟩
Molecular Therapy-Nucleic Acids, 2019, 16, pp.186-193. ⟨10.1016/j.omtn.2019.02.016⟩
Molecular Therapy-Nucleic Acids, Nature Publishing Group, 2019, 16, pp.186-193. ⟨10.1016/j.omtn.2019.02.016⟩
Molecular Therapy: Nucleic Acids, Vol 16, Iss, Pp 186-193 (2019)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids (16), 186-193. (2019)

Tetrafunctional block copolymers are molecules capable of complexing DNA. Although ineffective in vitro, studies in mice have shown that the tetrafunctional block copolymer 704 is a more efficient lung gene transfer agent than the cationic liposome G

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b91f894ca5e4145c1a99620c1d9a4255
https://www.hal.inserm.fr/inserm-02080870/file/CaballeroEq52019.pdf