Výsledky vyhledávání - "Anne Pfisterer"

Site-Selective Lysine Modification of Native Proteins and Peptides via Kinetically Controlled Labeling

Autor: Xi Chen, Kasturi Muthoosamy, Anne Pfisterer, Boris Neumann, Tanja Weil

Publikováno v: Bioconjugate Chemistry. 23:500-508

The site-selective modification of the proteins RNase A, lysozyme C, and the peptide hormone somatostatin is presented via a kinetically controlled labeling approach. A single lysine residue on the surface of these biomolecules reacts with an activat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f15328e6743411afa6a361c0ad985491
https://doi.org/10.1021/bc200556n

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Bioactive Unnatural Somatostatin Analogues through Bioorthogonal Iodo- and Ethynyl-Disulfide Intercalators

Autor: Anne Pfisterer, Xi Chen, Klaus Müllen, Tanja Weil, Klaus Eisele, Manfred Wagner

Publikováno v: Chemistry - A European Journal. 17:9697-9707

Iodo- and ethynyl-containing bisalkylating bioconjugation agents 5 and 8 were achieved and allow the introduction of reactive unnatural substituents into proteins and peptides whilst the bioactive 3D structure is retained. Derivatives of the peptide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98bc5841f69da6a4374f0ec73600f5a9
https://doi.org/10.1002/chem.201100287

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