Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Anne Pedata"'
Autor:
Haotian Zou, Varun Aggarwal, Glenn T. Stebbins, Martijn L. T. M. Müller, Jesse M. Cedarbaum, Anne Pedata, Diane Stephenson, Tanya Simuni, Sheng Luo
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 10, Pp 1382-1392 (2022)
Abstract The Movement Disorder Society revised version of the Unified Parkinson’s Disease Rating Scale (MDS‐UPDRS) parts 2 and 3 reflect patient‐reported functional impact and clinician‐reported severity of motor signs of Parkinson’s diseas
Externí odkaz:
https://doaj.org/article/ee3e3e53b9774dd6a46eb395e7981514
Autor:
Kirsi M. Kinnunen, Adam J. Schwarz, Emily C. Turner, Dorian Pustina, Emily C. Gantman, Mark F. Gordon, Richard Joules, Ariana P. Mullin, Rachael I. Scahill, Nellie Georgiou-Karistianis, The Huntington's Disease Regulatory Science Consortium (HD-RSC), Varun Aggarwal, Shazia Ali, Irina Antonijevic, Astri Arnesen, Nazem Atassi, Brian Beers, Beth Belluscio, Limor Ben Har, Angele Benard, Caroline Benn, Brian Bettencourt, Anu Bhattacharyya, Robi Blumenstein, Beth Borowsky, Bret Bostwick, Jackson Burton, Angelika Caputo, David Cooper, Brad Elmer, Rebecca Evans, Andrew Feigen, Terrence Fisher, Rebecca Fuller, Emily Gantman, Danielle Gartner, Michal Geva, Sandra Gonzalez, Adam Good, Mark Gordon, Jaya Goyal, Michael Hayden, Priyantha Herath, Steve Hersch, Jianying Hu, Elise Kayson, Eileen Koski, Bernhard Landwehrmeyer, Michelle Lax, Blair Leavitt, Dorothy Leong, Oren Levy, Enchi Liu, Jeff Long, Doug Macdonald, Jacqueline Major, Lahar Mehta, Tiago Mestre, Eric Miller, Christian Mueller, Catherine O'Riordan, Jennifer Panagoulias, Mike Panzara, Anne Pedata, Jennifer Petrillo-Billet, Dave Podskalny, Alisha Reader, Shelly Redman, Ralf Reilmann, Klaus Romero, Christopher Ross, Anne Rosser, Cristina Sampaio, Jan Samzelius, Scott Schobel, Adam Schwarz, Sudhir Sivakumaran, Jennie Socha, Glenn Stebbins, Julie Stout, Sarah Tabrizi, Emily Turner, Charles Venuto, Louise Vetter, Vissia Viglietta, Sarah Wahlstrom Helgren, Beth White, Ed Wild, George Yohrling, Maurice Zauderer
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Huntington's disease (HD) is an autosomal-dominant inherited neurodegenerative disorder that is caused by expansion of a CAG-repeat tract in the huntingtin gene and characterized by motor impairment, cognitive decline, and neuropsychiatric disturbanc
Externí odkaz:
https://doaj.org/article/ca6c677056d045fbbeff255dc7be3a75
Autor:
Caroline H. Williams-Gray, Diane Stephenson, Klaus Romero, Judith Anton, Ferdous Gheyas, Nathan J. Hanan, Jonas Weidemann, Minhua Yang, Malidi Ahamadi, Massimo Bani, Bob Stafford, Charles S. Venuto, Chao Chen, Vincent Thuillier, Ka Lai Yee, Gennaro Pagano, Monica Javidnia, Sreeraj Macha, Nitin Mehrotra, Vikram Sinha, Kenneth Marek, Yaming Hang, Hans Smit, Anne Pedata, Mussie Akalu, Babak Boroojerdi, David T. Dexter, Glenn T. Stebbins
Publikováno v:
Clinical Pharmacology & Therapeutics. 110:508-518
Leucine-rich repeat kinase 2 (LRRK2) inhibitors are currently in clinical development as interventions to slow progression of Parkinson's disease (PD). Understanding the rate of progression in PD as measured by both motor and non-motor features is pa
Autor:
Lauren Behman, Mark Lefever, Jerry Kosmeder, Larry E. Morrison, Robert L. Ochs, Esteban Roberts, Julia Ashworth-Sharpe, James Grille, Donald Johnson, Anne Pedata, Eric May, William Day
Publikováno v:
Laboratory Investigation. 97:104-113
Multiplexed analysis of multiple biomarkers in a tissue sample requires use of reporter dyes with specific spectral properties that enable discrimination of signals. Conventional chromogens with broad absorbance spectra, widely used in immunohistoche
Publikováno v:
Cancer Research. 74:525-525
The human genome encodes more than one thousand short (17-24 base) non-coding microRNA molecules which regulate diverse cellular functions. Several of these functions are also involved in tumorigenesis including cell growth, motility, and immune surv
Autor:
James R. Cook, Anne Pedata, Lisa M. Rimsza, Teresa Marafioti, Thomas M. Grogan, Roger A. Warnke, Sarah G. McGinn, Yasodha Natkunam, William Day
Publikováno v:
Diagnostic Pathology
Background: Detection of B cell clonality is useful for assisting in the diagnosis of B cell lymphomas. Clonality assessment can be accomplished through evaluation of KAPPA and LAMBDA light chain expression. Currently, only slide based methods are av