Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Anne N. Kovochich"'
Autor:
Anna R. Lay, Xin-Min Li, Timothy R. Donahue, Michael D. Arensman, Anne N. Kovochich, Samuel W. French, Nagesh Rao, David W. Dawson
Publikováno v:
Cancer. 119:529-539
BACKGROUND: The homeobox gene HOXB7 is overexpressed across a range of cancers and promotes tumorigenesis through varying effects on proliferation, survival, invasion, and angiogenesis. Although published microarray data suggest HOXB7 is overexpresse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bd6afe447f3a38ec0a414693fbf793e
https://doi.org/10.1002/cncr.27725
https://doi.org/10.1002/cncr.27725
Autor:
David J. Adams, David W. Dawson, Todd E. Sheetz, Benjamin T. Brett, Christopher Chin Kuan Yew, Nicola Waddell, Anne N. Kovochich, Karin S. Kassahn, David K. Chang, Jerrold M. Ward, Adam J. Dupuy, Neal G. Copeland, Karen M. Mann, Nancy A. Jenkins, Sean M. Grimmond, Alistair G. Rust, Michael A. Black, Andrew V. Biankin
Publikováno v:
Proceedings of the National Academy of Sciences. 109:5934-5941
Pancreatic cancer is one of the most deadly cancers affecting the Western world. Because the disease is highly metastatic and difficult to diagnosis until late stages, the 5-y survival rate is around 5%. The identification of molecular cancer drivers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0f4d3676aadf3699f67002afbe0409c
https://doi.org/10.1073/pnas.1202490109
https://doi.org/10.1073/pnas.1202490109
Autor:
Xin-Min Li, Timothy R. Donahue, Hong Wu, Linh M. Tran, David W. Dawson, Nanping Wu, Anne N. Kovochich, Reginald Hill, Yunfeng Li, James J. Farrell, Joseph Hargan Calvopina, Sanjeet G. Patel, Antreas Hindoyan
Publikováno v:
Clinical Cancer Research. 18:1352-1363
Purpose: To carry out an integrative profile of human pancreatic ductal adenocarcinoma (PDAC) to identify prognosis-significant genes and their related pathways. Experimental Design: A concordant survival-based whole genome in silico array analysis o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0533abb500c249ae32bbbc83fdca1a94
https://doi.org/10.1158/1078-0432.ccr-11-1539
https://doi.org/10.1158/1078-0432.ccr-11-1539
Autor:
Xin-Min Li, Michael D. Arensman, Anna R. Lay, Pei-Tzu Yang, Rima M. Kulikauskas, Randall T. Moon, Michael B. Major, Timothy R. Donahue, Anne N. Kovochich, Andy J. Chien, David W. Dawson
Publikováno v:
Oncogene, vol 33, iss 7
Oncogene
Oncogene
Developmental and cancer models show Wnt/β-catenin-dependent signaling mediates diverse phenotypic outcomes in the pancreas that are dictated by context, duration and strength of activation. While generally assumed to be pro-tumorigenic, it is uncle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbabf24e1523186e1d25ae2078d57d7c
https://escholarship.org/uc/item/88p764cn
https://escholarship.org/uc/item/88p764cn
Autor:
Samuel W. French, Timothy R. Donahue, Michael A. Arensman, Anne N. Kovochich, David W. Dawson
Publikováno v:
Tumor Biology.
HOX genes encode transcription factors that not only regulate normal growth and differentiation during embryonic development, but also promote oncogenesis through their aberrant expression and functional deregulation in cancer. Published microarray d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::156b1f16c4372cb76d9645a775bb8e60
https://doi.org/10.1158/1538-7445.panca2012-b50
https://doi.org/10.1158/1538-7445.panca2012-b50
Autor:
Anne N. Kovochich, Andy J. Chien, Michael D. Arensman, Rima M. Kulikauskas, David W. Dawson, Anna R. Lay
Publikováno v:
Tumor Biology.
Developmental and cancer models show Wnt/β-catenin signaling mediates diverse phenotypic outcomes in the pancreas dictated by its temporospatial context and relative levels of activation. While Wnt/β-catenin signaling is generally thought to promot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::181aba4931f0e04b8fab26d696d08d71
https://doi.org/10.1158/1538-7445.panca2012-b72
https://doi.org/10.1158/1538-7445.panca2012-b72