Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Anne N. Cowell"'
Autor:
Janette Reader, Mariëtte E. van der Watt, Dale Taylor, Claire Le Manach, Nimisha Mittal, Sabine Ottilie, Anjo Theron, Phanankosi Moyo, Erica Erlank, Luisa Nardini, Nelius Venter, Sonja Lauterbach, Belinda Bezuidenhout, Andre Horatscheck, Ashleigh van Heerden, Natalie J. Spillman, Anne N. Cowell, Jessica Connacher, Daniel Opperman, Lindsey M. Orchard, Manuel Llinás, Eva S. Istvan, Daniel E. Goldberg, Grant A. Boyle, David Calvo, Dalu Mancama, Theresa L. Coetzer, Elizabeth A. Winzeler, James Duffy, Lizette L. Koekemoer, Gregory Basarab, Kelly Chibale, Lyn-Marié Birkholtz
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Here, Reader et al. screen the Medicines for Malaria Venture Pandemic Response Box in parallel against Plasmodiumasexual and liver stage parasites, stage IV/V gametocytes, gametes, oocysts and as endectocides. They identify two potent transmission-bl
Externí odkaz:
https://doaj.org/article/469ad5b32c23403795a07ad1d5fdbabe
Autor:
Sabine Ottilie, Dale Taylor, Mariëtte van der Watt, Phanankosi Moyo, Lizette L. Koekemoer, Claire Le Manach, Daniel Opperman, James Duffy, Erica Erlank, Kelly Chibale, Sonja B Lauterbach, Lyn-Marie Birkholtz, Daniel E. Goldberg, Nimisha Mittal, Jessica I. Connacher, Lindsey M. Orchard, Ashleigh van Heerden, Natalie J. Spillman, Theresa L. Coetzer, Gregory S. Basarab, André Horatscheck, David Calvo, Elizabeth A. Winzeler, Anjo Theron, Janette Reader, Dalu Mancama, Nelius Venter, Grant A. Boyle, Eva S. Istvan, Manuel Llinás, Belinda C. Bezuidenhout, Luisa Nardini, Anne N. Cowell
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Chemical matter is needed to target the divergent biology associated with the different life cycle stages of Plasmodium. Here, we report the parallel de novo screening of the Medicines for Malaria Venture (MMV) Pandemic Response Box against Plasmodiu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65542ff95a46fa520faa2ebd28c4b18c
https://doi.org/10.1038/s41467-020-20629-8
https://doi.org/10.1038/s41467-020-20629-8
Autor:
Lyn-Marie Birkholtz, Keith Al-Hasani, Mitchell B Batty, Belinda Joan Morahan, Jose F. Garcia-Bustos, Victoria C. Corey, Christian Doerig, Elizabeth A. Winzeler, Clarissa Abrie, Anne N. Cowell, Jandeli Niemand
Publikováno v:
Communications Biology
Communications Biology, Vol 3, Iss 1, Pp 1-10 (2020)
Communications Biology, Vol 3, Iss 1, Pp 1-10 (2020)
Mitosis has been validated by numerous anti-cancer drugs as being a druggable process, and selective inhibition of parasite proliferation provides an obvious opportunity for therapeutic intervention against malaria. Mitosis is controlled through the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbc328f026bdbecc17496f5adfdc3803
https://doi.org/10.1038/s42003-020-01424-z
https://doi.org/10.1038/s42003-020-01424-z