Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Anne Mobergslien"'
Autor:
Axel Berg-Larsen, Anne Mobergslien, Ingrid Moen, Gebregziabher Petros, Alexander Kristian, Kristine Sponheim Gunvaldsen, Véronique Cruciani, Katrine Wickstroem, Roger Malerbakken Bjerke, Jenny Karlsson, Alan Cuthbertson
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Targeted thorium-227 conjugates comprise the combination of a monoclonal antibody with specificity for a tumor cell antigen and a 3,2-HOPO chelator enabling complexation of thorium-227 (Th-227). The radiolabeled conjugate functions as an effective de
Externí odkaz:
https://doaj.org/article/35a8807e6b7b47ed8e2cafef073f9330
Autor:
Pascale Lejeune, Véronique Cruciani, Axel Berg-Larsen, Andreas Schlicker, Anne Mobergslien, Lisa Bartnitzky, Sandra Berndt, Sabine Zitzmann-Kolbe, Claudia Kamfenkel, Stefan Stargard, Stefanie Hammer, Jennifer S Jørgensen, Malene Jackerott, Carsten H Nielsen, Christoph A Schatz, Hartwig Hennekes, Jenny Karlsson, Alan S Cuthbertson, Dominik Mumberg, Urs B Hagemann
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 10 (2021)
Externí odkaz:
https://doaj.org/article/05e7344e8ce54a129a43af0ebbd6ec6f
Autor:
Mouldy Sioud, Marta Nyakas, Stein Sæbøe-Larssen, Anne Mobergslien, Steinar Aamdal, Gunnar Kvalheim
Publikováno v:
Case Reports in Medicine, Vol 2016 (2016)
Indoleamine 2,3-dioxygenase (IDO) expression in dendritic cells (DCs) inhibits T-cell activation and promotes T-cell differentiation into regulatory T-cells. Moreover, IDO expression promotes resistance to immunotherapies targeting immune checkpoints
Externí odkaz:
https://doaj.org/article/e405f936753c43219f659d34e32ad15d
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 2, Iss , Pp - (2015)
Antibody-dependent cellular cytotoxicity (ADCC), a key effector function for the clinical effectiveness of monoclonal antibodies, is triggered by the engagement of the antibody Fc domain with the Fcγ receptors expressed by innate immune cells such
Externí odkaz:
https://doaj.org/article/b6cd2cb1bcd24d088d44524d215b570c
Autor:
Alan S. Cuthbertson, Karl Ziegelbauer, Dominik Mumberg, Olav B. Ryan, Roger M. Bjerke, Jenny Karlsson, Hartwig Hennekes, Steinar Uran, Roger Smeets, Sven Golfier, Christoph Kneip, Christoph A. Schatz, Katrine Wickstroem, Véronique Cruciani, Anne Mobergslien, Alexander Kristian, Joachim Schuhmacher, Christine Ellingsen, Urs B. Hagemann
The file contains Supporting Figures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01f92bea6c9a4be445515d2bb9d07c53
https://doi.org/10.1158/1078-0432.22469934.v1
https://doi.org/10.1158/1078-0432.22469934.v1
Autor:
Alan S. Cuthbertson, Karl Ziegelbauer, Dominik Mumberg, Olav B. Ryan, Roger M. Bjerke, Jenny Karlsson, Hartwig Hennekes, Steinar Uran, Roger Smeets, Sven Golfier, Christoph Kneip, Christoph A. Schatz, Katrine Wickstroem, Véronique Cruciani, Anne Mobergslien, Alexander Kristian, Joachim Schuhmacher, Christine Ellingsen, Urs B. Hagemann
The file contains Supporting Tables.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b85eabb5ba146556946119f951b1f86d
https://doi.org/10.1158/1078-0432.22469928.v1
https://doi.org/10.1158/1078-0432.22469928.v1
Autor:
Alan S. Cuthbertson, Karl Ziegelbauer, Dominik Mumberg, Olav B. Ryan, Roger M. Bjerke, Jenny Karlsson, Hartwig Hennekes, Steinar Uran, Roger Smeets, Sven Golfier, Christoph Kneip, Christoph A. Schatz, Katrine Wickstroem, Véronique Cruciani, Anne Mobergslien, Alexander Kristian, Joachim Schuhmacher, Christine Ellingsen, Urs B. Hagemann
Purpose:Targeted thorium-227 conjugates (TTC) represent a new class of molecules for targeted alpha therapy (TAT). Covalent attachment of a 3,2-HOPO chelator to an antibody enables specific complexation and delivery of the alpha particle emitter thor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c8d604b059f9778e1c4ed95e26f2f98
https://doi.org/10.1158/1078-0432.c.6527394.v1
https://doi.org/10.1158/1078-0432.c.6527394.v1
Autor:
Alan S. Cuthbertson, Karl Ziegelbauer, Dominik Mumberg, Olav B. Ryan, Roger M. Bjerke, Jenny Karlsson, Hartwig Hennekes, Steinar Uran, Roger Smeets, Sven Golfier, Christoph Kneip, Christoph A. Schatz, Katrine Wickstroem, Véronique Cruciani, Anne Mobergslien, Alexander Kristian, Joachim Schuhmacher, Christine Ellingsen, Urs B. Hagemann
The file contains description of Supporting Methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6a100d6b45ed95e4fe5bf2e9c82fdcb
https://doi.org/10.1158/1078-0432.22469931.v1
https://doi.org/10.1158/1078-0432.22469931.v1
Autor:
Véronique Cruciani, Dominik Mumberg, Axel Berg-Larsen, Carsten H. Nielsen, Andreas Schlicker, Sandra Berndt, Anne Mobergslien, Sabine Zitzmann-Kolbe, Stefan Stargard, Jenny Karlsson, Christoph A. Schatz, Claudia Kamfenkel, Pascale Lejeune, Alan Cuthbertson, Malene Jackerott, Lisa Bartnitzky, Urs B. Hagemann, Hartwig Hennekes, Jennifer S Jørgensen, Stefanie Hammer
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 10 (2021)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
BackgroundTargeted thorium-227 conjugates (TTCs) are an emerging class of targeted alpha therapies (TATs). Their unique mode of action (MoA) is the induction of difficult-to-repair clustered DNA double-strand breaks. However, thus far, their effects
Autor:
Anne, Mobergslien, Mouldy, Sioud
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2115
Although RNA interference is widely used for gene silencing, unintended gene modulation generated by off-target effects represents a major barrier to its applications in biology and medicine. Off-targeting can be induced by both the sense and antisen