Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Anne Minnich"'
Autor:
Elizabeth A. Brown, Anne Minnich, Arun J. Sanyal, Rohit Loomba, Shuyan Du, John Schwarz, Richard L. Ehman, Morten Karsdal, Diana J. Leeming, Giovanni Cizza, Edgar D. Charles
Publikováno v:
JHEP Reports, Vol 5, Iss 4, Pp 100661- (2023)
Background & Aims: FALCON 1 was a phase IIb study of pegbelfermin in patients with non-alcoholic steatohepatitis (NASH) and stage 3 fibrosis. This FALCON 1 post hoc analysis aimed to further assess the effect of pegbelfermin on NASH-related biomarker
Externí odkaz:
https://doaj.org/article/20c05779d241409e8ccca9f583b55976
Autor:
Benjamin E. Decato, Diana Julie Leeming, Jannie Marie Bülow Sand, Aryeh Fischer, Shuyan Du, Scott M. Palmer, Morten Karsdal, Yi Luo, Anne Minnich
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-12 (2022)
Abstract Background Idiopathic pulmonary fibrosis (IPF) is a debilitating lung disease with limited treatment options. A phase 2 trial (NCT01766817) showed that twice-daily treatment with BMS-986020, a lysophosphatidic acid receptor 1 (LPA1) antagoni
Externí odkaz:
https://doaj.org/article/f5eb12194dce4c0a95bc6daf33d7db46
Autor:
Joelle M. Onorato, Petia Shipkova, Anne Minnich, Anne-Françoise Aubry, John Easter, Adrienne Tymiak
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 8, Pp 1784-1796 (2014)
Lysophosphatidic acids (LPAs) are biologically active signaling molecules involved in the regulation of many cellular processes and have been implicated as potential mediators of fibroblast recruitment to the pulmonary airspace, pointing to possible
Externí odkaz:
https://doaj.org/article/7b3b0a4eeddf4490922069ee646f0c8c
Autor:
Elizabeth M King, Joanna E Chivers, Christopher F Rider, Anne Minnich, Mark A Giembycz, Robert Newton
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53936 (2013)
Binding of glucocorticoid to the glucocorticoid receptor (GR/NR3C1) may repress inflammatory gene transcription via direct, protein synthesis-independent processes (transrepression), or by activating transcription (transactivation) of multiple anti-i
Externí odkaz:
https://doaj.org/article/af55fea600b245048ca795fb24f2ed93
Autor:
Tamera J Corte, Lisa Lancaster, Jeffrey J Swigris, Toby M Maher, Jonathan G Goldin, Scott M Palmer, Takafumi Suda, Takashi Ogura, Anne Minnich, Xiaojiang Zhan, Giridhar S Tirucherai, Brandon Elpers, Hong Xiao, Hideaki Watanabe, R Adam Smith, Edgar D Charles, Aryeh Fischer
Publikováno v:
BMJ Open Respiratory Research
BMJ Open Respiratory Research, vol 8, iss 1
BMJ Open Respiratory Research, vol 8, iss 1
IntroductionIdiopathic pulmonary fibrosis (IPF) and non-IPF, progressive fibrotic interstitial lung diseases (PF-ILD), are associated with a progressive loss of lung function and a poor prognosis. Treatment with antifibrotic agents can slow, but not
Autor:
Benjamin E, Decato, Diana Julie, Leeming, Jannie Marie Bülow, Sand, Aryeh, Fischer, Shuyan, Du, Scott M, Palmer, Morten, Karsdal, Yi, Luo, Anne, Minnich
Publikováno v:
Respiratory research. 23(1)
Idiopathic pulmonary fibrosis (IPF) is a debilitating lung disease with limited treatment options. A phase 2 trial (NCT01766817) showed that twice-daily treatment with BMS-986020, a lysophosphatidic acid receptor 1 (LPASerum levels of nine ECM-neoepi
Autor:
Li Chen, Elizabeth Brown, Anne Minnich, Vipul Baxi, Dimple Pandya, Shuyan Du, Edgar Charles, Zachary Goodman, Mathieu Petitjean, Arun Sanyal
Publikováno v:
Journal of Hepatology. 77:S446
Autor:
Matthew W. Foster, M. Arthur Moseley, Kent J. Weinhold, Kelly Plonk, Jamie L. Todd, Anne Minnich, Laurie D. Snyder, Robert M. Townsend, Lake Morrison, J. Will Thompson, Erik J. Soderblom
Publikováno v:
Journal of Proteome Research. 14:1238-1249
The proteomic analysis of bronchoalveolar lavage fluid (BALF) can give insight into pulmonary disease pathology and response to therapy. Here, we describe the first gel-free quantitative analysis of BALF in idiopathic pulmonary fibrosis (IPF), a chro
Autor:
Xin Chen, Poli Gregory B, Joseph T. Tsay, Jiesheng Kang, Ying Zhang, Anne Minnich, Keith Sides, Qingping Wang, Yong Mi Choi-Sledeski, Patrick Wai-Kwok Shum, Guyan Liang, Vasant Kumar
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:1606-1610
Tropanylamide was investigated as a possible scaffold for β-tryptase inhibitors with a basic benzylamine P1 group and a substituted thiophene P4 group. Comparing to piperidinylamide, the tropanylamide scaffold is much more rigid, which presents less
Autor:
Anne-Françoise Aubry, Petia Shipkova, Anne Minnich, John A. Easter, Adrienne A. Tymiak, Joelle M. Onorato
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 8, Pp 1784-1796 (2014)
Lysophosphatidic acids (LPAs) are biologically active signaling molecules involved in the regulation of many cellular processes and have been implicated as potential mediators of fibroblast recruitment to the pulmonary airspace, pointing to possible
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c59e12919e197f8d56b2c1254af4c77b
https://europepmc.org/articles/PMC4109772/
https://europepmc.org/articles/PMC4109772/