Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Anne McLaren-Douglas"'
Autor:
Hayley E. Francies, Andrew Barthorpe, Anne McLaren-Douglas, William J. Barendt, Mathew J. Garnett
Drug sensitivity testing utilizing preclinical disease models such as cancer cell lines is an important and widely used tool for drug development. Importantly, when combined with molecular data such as gene copy number variation or somatic coding mut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e679483ed56661d005803324b930d15d
https://doi.org/10.17504/protocols.io.bpsgmnbw
https://doi.org/10.17504/protocols.io.bpsgmnbw
Autor:
Hayley E. Francies, Andrew Barthorpe, Anne McLaren-Douglas, William J. Barendt, Mathew J. Garnett
Publikováno v:
Methods in Molecular Biology ISBN: 9781493976164
Drug sensitivity testing utilizing preclinical disease models such as cancer cell lines is an important and widely used tool for drug development. Importantly, when combined with molecular data such as gene copy number variation or somatic coding mut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f17cb3f98cc72d6ea7e81453ebbc526
https://europepmc.org/articles/PMC6527507/
https://europepmc.org/articles/PMC6527507/
Autor:
Alejandra Bruna, Oscar M. Rueda, Wendy Greenwood, Ankita Sati Batra, Maurizio Callari, Rajbir Nath Batra, Katherine Pogrebniak, Jose Sandoval, John W. Cassidy, Ana Tufegdzic-Vidakovic, Stephen-John Sammut, Linda Jones, Elena Provenzano, Richard Baird, Peter Eirew, James Hadfield, Matthew Eldridge, Anne McLaren-Douglas, Andrew Barthorpe, Howard Lightfoot, Mark J. O’Connor, Joe Gray, Javier C
Publikováno v:
Cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=r3c4b2081b22::429ede094ddacfeac1f7281b5cf0bf62
Autor:
Xeni Mitropoulos, Jae Won Chang, Daniel A. Haber, Jeffrey Settleman, Wanjuan Yang, I. Richard Thompson, Julio Saez-Rodriguez, Nathanael S. Gray, Olivier Delattre, Jeffrey A. Engelman, Qingsong Liu, Sonja J. Heidorn, José Baselga, Michael R. Stratton, Karl P. Lawrence, Helen Davies, Stephen R. Lutz, Li Chen, Helen Thi, Graham R. Bignell, Randy J. Milano, Anne McLaren-Douglas, Anahita Dastur, Sridhar Ramaswamy, Sreenath V. Sharma, Jesse A. Stevenson, Patricia Greninger, Jessica L. Boisvert, King Wai Lau, Xi Luo, Tatiana Mironenko, Xianming Deng, Christopher Greenman, Fiona Kogera, P. Andrew Futreal, Tinghu Zhang, Patrick O’Brien, Syd Barthorpe, F Jewitt, Ultan McDermott, Hwan Geun Choi, Mathew J. Garnett, Ivan Stamenkovic, Francesco Iorio, Wooyoung Hur, Stacey Price, Jorge Soares, Laura Richardson, Wenjun Zhou, Cyril H. Benes, Ah Ting Tam, Adam Butler, Elena J. Edelman, Didier Surdez
Publikováno v:
Nature
Nature, vol. 483, no. 7391, pp. 570-575
Nature, vol. 483, no. 7391, pp. 570-575
Clinical responses to anticancer therapies are often restricted to a subset of patients. In some cases, mutated cancer genes are potent biomarkers for responses to targeted agents. Here, to uncover new biomarkers of sensitivity and resistance to canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d30c7a49863ef53126248c5b26aafba
http://europepmc.org/articles/PMC3349233
http://europepmc.org/articles/PMC3349233
Autor:
Apollo Pronk, Julio Saez-Rodriguez, Sina Bartfeld, Anne McLaren-Douglas, Marc van de Wetering, Michael R. Stratton, Hayley E. Francies, Joost van Gorp, Lee Lichtenstein, Vivian S. W. Li, Scott L. Carter, Gergana Bounova, Peter van Sluis, Joyce Blokker, Winan J. van Houdt, Aaron McKenna, Joshua M. Francis, Chandra Sekhar Pedamallu, Lodewyk F. A. Wessels, Matthew Meyerson, Gad Getz, Amaro Taylor-Weiner, Robert G.J. Vries, Alexander van Oudenaarden, Hans Clevers, Jan Koster, Sara Seepo, Chip Stewart, Francesco Iorio, Richard Volckman, Ultan McDermott, Sridevi Jaksani, Mathew J. Garnett, Rogier Versteeg, Lennart Kester, Michael S. Lawrence, Kristian Cibulskis
Publikováno v:
Cell, 161(4), 933-45. Elsevier B.V.
Cell, 161(4), 933-945. Cell Press
Cell, 161(4), 933. Cell Press
Cell, 161(4), 933-945. Cell Press
Cell, 161(4), 933. Cell Press
SummaryIn Rspondin-based 3D cultures, Lgr5 stem cells from multiple organs form ever-expanding epithelial organoids that retain their tissue identity. We report the establishment of tumor organoid cultures from 20 consecutive colorectal carcinoma (CR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a4e7a4be1e42b63ed70dda87f1c635a
https://dspace.library.uu.nl/handle/1874/333261
https://dspace.library.uu.nl/handle/1874/333261