Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Anne Marowsky"'
Autor:
Michael Arand, Anne Marowsky
Publikováno v:
mBio, Vol 8, Iss 2 (2017)
Externí odkaz:
https://doaj.org/article/9807790391874d3a807234ec6920814e
Publikováno v:
Biosensors, Vol 9, Iss 1, p 33 (2019)
In previous studies, we encountered substantial problems using the CFP_YFP Förster resonance energy transfer (FRET) pair to analyze protein proximity in the endoplasmic reticulum of live cells. Bleed-through of the donor emission into the FRET chann
Externí odkaz:
https://doaj.org/article/5b154a00d6e348129a1046ca8757751a
Autor:
Martina Decker, Magdalena Adamska, Annette Cronin, Francesca Di Giallonardo, Julia Burgener, Anne Marowsky, John R. Falck, Christophe Morisseau, Bruce D. Hammock, Artiom Gruzdev, Darryl C. Zeldin, Michael Arand
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 10, Pp 2038-2045 (2012)
Epoxide hydrolases are a small superfamily of enzymes important for the detoxification of chemically reactive xenobiotic epoxides and for the processing of endogenous epoxides that act as signaling molecules. Here, we report the identification of two
Externí odkaz:
https://doaj.org/article/22e3e40ce63244a59f9b8da9d7dde51b
Autor:
Nandkishor Mule, Anne Marowsky, Giovanni Pellegrini, Imke Meyer, Michael Arand, Kira Erismann-Ebner
Publikováno v:
Archives of Toxicology
Microsomal and soluble epoxide hydrolase (mEH and sEH) fulfill apparently distinct roles: Whereas mEH detoxifies xenobiotics, sEH hydrolyzes fatty acid (FA) signaling molecules and is thus implicated in a variety of physiological functions. These epo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a27349d4595e22bd3c566fe5d347bed
https://doi.org/10.1007/s00204-017-2060-4
https://doi.org/10.1007/s00204-017-2060-4
Autor:
Anne Marowsky, Michael Arand
Epoxide hydrolases (EHs) metabolize highly reactive epoxides with mutagenic and carcinogenic potential to the less reactive corresponding diols and are therefore traditionally viewed as detoxicating enzymes. In few instances, however, the diols thems
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d4e3a280f4c47c40719c93822a5b03b
https://doi.org/10.5167/uzh-150636
https://doi.org/10.5167/uzh-150636
Publikováno v:
Neuropharmacology. 123
Recent studies suggest a role for the arachidonic acid-derived epoxyeicosatrienoic acids (EETs) in attenuating epileptic seizures. However, their effect on neurotransmission has never been investigated in detail. Here, we studied how 11,12- and 14,15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdeb813a207f81964cd31495496d5600
https://pubmed.ncbi.nlm.nih.gov/28526610
https://pubmed.ncbi.nlm.nih.gov/28526610
Publikováno v:
Biosensors
Biosensors, Vol 9, Iss 1, p 33 (2019)
Volume 9
Issue 1
Biosensors, Vol 9, Iss 1, p 33 (2019)
Volume 9
Issue 1
In previous studies, we encountered substantial problems using the CFP_YFP Fö
rster resonance energy transfer (FRET) pair to analyze protein proximity in the endoplasmic reticulum of live cells. Bleed-through of the donor emission into the F
rster resonance energy transfer (FRET) pair to analyze protein proximity in the endoplasmic reticulum of live cells. Bleed-through of the donor emission into the F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4ff4f4e0beafdddff1a32c2c6b1e862
https://doi.org/10.3390/bios9010033
https://doi.org/10.3390/bios9010033
Autor:
Michael Arand, Diana Kindler, Sibylle Rutishauser, Ernesto Bockamp, Markus Rudin, Karen Haenel, Nandkishor Mule, Rosario Heck, Anne Marowsky
Publikováno v:
Arch Toxicol
Archives of Toxicology
Archives of Toxicology
Microsomal epoxide hydrolase (mEH) is a detoxifying enzyme for xenobiotic compounds. Enzymatic activity of mEH can be greatly increased by a point mutation, leading to an E404D amino acid exchange in its catalytic triad. Surprisingly, this variant is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::089f281e67a1283c5c5221b74e385f06
https://doi.org/10.5167/uzh-126341
https://doi.org/10.5167/uzh-126341
Publikováno v:
Journal of Neuroscience. 32:8611-8619
GABAergic inhibition in the amygdala is essential in regulating fear and anxiety. Although fast “phasic” inhibition arising through the activation of postsynaptic GABA(A) receptors (GABA(A)Rs) has been well described in the amygdala, much less is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec0b9c7d490382c22bef13366f16c20a
https://doi.org/10.1523/jneurosci.4404-11.2012
https://doi.org/10.1523/jneurosci.4404-11.2012