Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Anne Marie Krachler"'
Autor:
Natalie Sirisaengtaksin, Eloise J. O'Donoghue, Sara Jabbari, Andrew J. Roe, Anne Marie Krachler
Publikováno v:
mSphere, Vol 8, Iss 6 (2023)
ABSTRACTOuter membrane vesicles (OMVs) are proteoliposomes shed by Gram-negative bacteria. Their secretion is enhanced by the transition into the intra-host milieu, and OMVs play critical roles during pathogenesis. Enterohemorrhagic Escherichia coli
Externí odkaz:
https://doaj.org/article/b235a442b5504fafa8012d2a6503453f
Autor:
Anne Marie Krachler, Natalie Sirisaengtaksin, Pauline Monteith, C. E. Timothy Paine, Christopher J. Coates, Jenson Lim
Publikováno v:
Virulence, Vol 12, Iss 1, Pp 638-653 (2021)
Adhesins facilitate bacterial colonization and invasion of host tissues and are considered virulence factors, but their impact on immune-mediated damage as a driver of pathogenesis remains unclear. Yersinia pseudotuberculosis encodes for a multivalen
Externí odkaz:
https://doaj.org/article/34afe04918f4471fb10f5a2419c1e324
Autor:
Selina Patel, Anne Marie Krachler
Publikováno v:
Journal of Microbiology & Biology Education, Vol 17, Iss 2, Pp 302-304 (2016)
OFSTED repeatedly finds the teaching of sexually transmitted infections in secondary schools ‘inadequate’ across the UK (3). This is thought to be due to a number of reasons, including the fact that staff teaching this topic feel inadequately pre
Externí odkaz:
https://doaj.org/article/7e0176b3836646f8a381602927b2eddb
Autor:
Rachael Collins, Anne Marie Krachler
Publikováno v:
Journal of Microbiology & Biology Education, Vol 16, Iss 2, Pp 263-265 (2015)
School students lack information about STEM based careers, a subject that is not sufficiently embedded in the national science curriculum. As a result, students feel they receive insufficient advice to support their choice of subjects at GCSE level a
Externí odkaz:
https://doaj.org/article/dfb8322ba51944148dde071a804d41f4
Autor:
Eloise J O'Donoghue, Natalie Sirisaengtaksin, Douglas F Browning, Ewa Bielska, Mohammed Hadis, Francisco Fernandez-Trillo, Luke Alderwick, Sara Jabbari, Anne Marie Krachler
Publikováno v:
PLoS Pathogens, Vol 13, Iss 11, p e1006760 (2017)
Outer membrane vesicles are nano-sized microvesicles shed from the outer membrane of Gram-negative bacteria and play important roles in immune priming and disease pathogenesis. However, our current mechanistic understanding of vesicle-host cell inter
Externí odkaz:
https://doaj.org/article/316fc782566a4c92a3ea23e9d66593a4
Autor:
Daniel H. Stones, Alexander G. J. Fehr, Laurel Thompson, Jacqueline Rocha, Nicolas Perez-Soto, Vipin T. P. Madhavan, Kerstin Voelz, Anne Marie Krachler
Publikováno v:
mSphere, Vol 2, Iss 5 (2017)
ABSTRACT Foodborne infections with enterohemorrhagic Escherichia coli (EHEC) are a major cause of diarrheal illness in humans and can lead to severe complications such as hemolytic uremic syndrome. Cattle and other ruminants are the main reservoir of
Externí odkaz:
https://doaj.org/article/78b7931a3a8f4b148433f87779e57512
Autor:
Lingling Zhang, Anne Marie Krachler, Christopher A. Broberg, Yan Li, Hamid Mirzaei, Christopher J. Gilpin, Kim Orth
Publikováno v:
Cell Reports, Vol 1, Iss 5, Pp 453-460 (2012)
Vibrio spp. are associated with infections caused by contaminated food and water. A type III secretion system (T3SS2) is a shared feature of all clinical isolates of V. parahaemolyticus and some V. cholerae strains. Despite its being responsible for
Externí odkaz:
https://doaj.org/article/fdc34c9b261c4b2aad7d2a0ad87933c9
Autor:
Jenson Lim, Daniel H Stones, Catherine Alice Hawley, Charlie Anne Watson, Anne Marie Krachler
Publikováno v:
PLoS Pathogens, Vol 10, Iss 9, p e1004421 (2014)
Vibrio parahaemolyticus is an emerging bacterial pathogen which colonizes the gastrointestinal tract and can cause severe enteritis and bacteraemia. During infection, V. parahaemolyticus primarily attaches to the small intestine, where it causes exte
Externí odkaz:
https://doaj.org/article/3eb9d9490ec443d6b6cad9fc30de5c14
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e81216 (2013)
Adhesion inhibitors that block the attachment of pathogens to host tissues may be used synergistically with or as an alternative to antibiotics. The wide-spread bacterial adhesin Multivalent Adhesion Molecule (MAM) 7 has recently emerged as a candida
Externí odkaz:
https://doaj.org/article/8c3f9ffe299146dd8f1b166b2ed54e40
Mathematical modelling of the antibiotic-induced morphological transition of Pseudomonas aeruginosa.
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 2, p e1006012 (2018)
Here we formulate a mechanistic mathematical model to describe the growth dynamics of P. aeruginosa in the presence of the β-lactam antibiotic meropenem. The model is mechanistic in the sense that carrying capacity is taken into account through the
Externí odkaz:
https://doaj.org/article/f1a4454996d94d2f986ef313b5068d04