Voxel-Based Statistical Analysis of 3D Immunostained Tissue Imaging

Autor: Michel E. Vandenberghe, Nicolas Souedet, Anne-Sophie Hérard, Anne-Marie Ayral, Florent Letronne, Yaël Balbastre, Elmahdi Sadouni, Philippe Hantraye, Marc Dhenain, Frédérique Frouin, Jean-Charles Lambert, Thierry Delzescaux

Publikováno v: Frontiers in Neuroscience, Vol 12 (2018)

Recently developed techniques to visualize immunostained tissues in 3D and in large samples have expanded the scope of microscopic investigations at the level of the whole brain. Here, we propose to adapt voxel-based statistical analysis to 3D high-r

Externí odkaz: https://doaj.org/article/a8dd82f630da4444b84650b7df9ba473

ADAM30 Downregulates APP-Linked Defects Through Cathepsin D Activation in Alzheimer's Disease

Autor: Pierre Dourlen, Yves Lemoine, Amandine Flaig, Frédéric Checler, Anne Marie Ayral, Jean-Charles Lambert, Kris Gevaert, Mathias Laga, Fanny Eysert, Tiago Mendes, David M. A. Mann, Linda Chami, Anne Sophie Hérard, Thierry Delzescaux, Franck Lafont, Florie Demiautte, Franck Hansmannel, Benoit Deprez, Charlotte Delay, David Hot, Florence Leroux, Bart Dermaut, Philippe Amouyel, Ludovic Huot, Yoann Sottejeau, Florence Pasquier, Nicolas Souedet, Florent Letronne, Charlotte Bauer, Marc Dhenain, Marie Lesaffre, Geoffroy Laumet, Nicolas Malmanche, David Tulasne, Claudine Berr, Rebecca Deprez, Julie Dumont, Elisabeth Werkmeister, Michel E. Vandenberghe, Jean Jacques Hauw, Julien Chapuis

Publikováno v: EBioMedicine
EBioMedicine, 2016, 9, pp.278-292. ⟨10.1016/j.ebiom.2016.06.002⟩
Letronne, F, Laumet, G, Ayral, A-M, Chapuis, J, Demiautte, F, Laga, M, Vandenberghe, M, Malmanche, N, Leroux, F, Eysert, F, Sottejeau, Y, Chami, L, Flaig, A, Bauer, C, Dourlen, P, Lesaffre, M, Delay, C, Huot, L, Dumont, J, Werkmeister, E, Lafont, F, Mendes, T, Hansmannel, F, Dermaut, B, Deprez, B, Hérard, A-S, Dhenain, M, Souedet, N, Pasquier, F, Tulasne, D, Berr, C, Hauw, J-J, Lemoine, Y, Amouyel, P, Mann, D, Déprez, R, Checler, F, Hot, D, Delzescaux, T, Gevaert, K & Lambert, J-C 2016, ' ADAM30 Downregulates APP-Linked Defects Through Cathepsin D Activation in Alzheimer's Disease ', EBioMedicine . https://doi.org/10.1016/j.ebiom.2016.06.002
EBioMedicine, Elsevier, 2016, 9, pp.278-292. ⟨10.1016/j.ebiom.2016.06.002⟩
EBioMedicine, Vol 9, Iss C, Pp 278-292 (2016)
EBIOMEDICINE

Although several ADAMs (A disintegrin-like and metalloproteases) have been shown to contribute to the amyloid precursor protein (APP) metabolism, the full spectrum of metalloproteases involved in this metabolism remains to be established. Transcripto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a9bf8d295c4426a333c53668484f520
https://pubmed.ncbi.nlm.nih.gov/27333034

A panel of optimized primers and positive-control DNAs for PCR detection of common biological contaminants in mouse cell lines and tissue samples

Autor: Anne-Marie Ayral, Sara Wells, T. Neil Dear, Michael Cheeseman, Sarah Clarkson

Publikováno v: Lab Animal. 35:31-36

PCR-based testing for infectious agents in mouse cell lines and tissues has recently been developed as an alternative to the traditional MAP test. One drawback to currently available PCR-based assays is the lack of appropriate positive controls for P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67a442589ff649b50cf00a5adb35b6d9
https://doi.org/10.1038/laban0906-31

P3‐012: Bridging integrator 1 (BIN1) as a new partner of Tau?

Autor: Philippe Amouyel, Julien Chapuis, Bart Dermaut, Anais Mounier, Céline Bellenguez, Benjamin Grenier-Bolay, Florent Letronne, Franck Hansmannel, Anne-Marie Ayral, Jean-Charles Lambert, Florie Demiautte

Publikováno v: Alzheimer's & Dementia. 8

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::49503141744f6d538f226825c2565981
https://doi.org/10.1016/j.jalz.2012.05.1230

P2‐233: Assessment of BIN1 involvement in the Alzheimer's Disease pathophysiological process

Autor: Philippe Amouyel, Benjamin Grenier-Boley, Anne-Marie Ayral, Jean-Charles Lambert, Marie Eve Maturski, Anais Mounier, Frédéric Checler, Bart Dermaut, Florent Letronne, Franck Hansmannel, Luc Buée, Marc Gistelinck

Publikováno v: Alzheimer's & Dementia. 7

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::700fe636c3d4b66321810dbac2ffc0ff
https://doi.org/10.1016/j.jalz.2011.05.1117