Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Anne Margrete Øyan"'
Autor:
Yaping Hua, Xing Yuan, Yun-heng Shen, Jinxin Wang, Waqas Azeem, Shuo Yang, Alexandra Gade, Seyed Mohammad Lellahi, Anne Margrete Øyan, Xisong Ke, Wei-dong Zhang, Karl-Henning Kalland
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Our drug discovery model has identified two novel STAT3 SH2 domain inhibitors 323–1 and 323–2 (delavatine A stereoisomers) in a series of experiments. In silico computational modeling, drug affinity responsive target stability (DARTS), and fluore
Externí odkaz:
https://doaj.org/article/480e443ab8d44490b85f8aa0b7dc914b
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The transcription factor β-catenin is able to induce tolerogenic/anti-inflammatory features in different types of dendritic cells (DCs). Monocyte-derived dendritic cells (moDCs) have been widely used in dendritic cell-based cancer therapy, but so fa
Externí odkaz:
https://doaj.org/article/62ac5584547a4938b5aea5d686aa41d9
Autor:
Waqas Azeem, Jan Roger Olsen, Margrete Reime Hellem, Yaping Hua, Kristo Marvyin, Xisong Ke, Anne Margrete Øyan, Karl-Henning Kalland
Publikováno v:
Biomedicines, Vol 10, Iss 2, p 473 (2022)
GATA2 has been shown to be an important transcription factor together with androgen receptor (AR) in prostate cancer cells. Less is known about GATA2 in benign prostate epithelial cells. We have investigated if GATA2 exogenous expression in prostate
Externí odkaz:
https://doaj.org/article/8df1866ef7084d4086ab35156a649e34
Autor:
Waqas Azeem, Ragnhild Maukon Bakke, Benjamin Gabriel, Silke Appel, Anne Margrete Øyan, Karl-Henning Kalland
Publikováno v:
Biomedicines, Vol 9, Iss 8, p 949 (2021)
Modulation of β-catenin signaling has attractive therapeutic potential in cancer immunotherapy. Several studies have found that β-catenin can mediate immune evasion in cancer and promote anti-inflammatory features of antigen-presenting dendritic ce
Externí odkaz:
https://doaj.org/article/f3554cdd195d4398b479dfe788feb3f4
Autor:
Waqas Azeem, Margrete Reime Hellem, Jan Roger Olsen, Yaping Hua, Kristo Marvyin, Yi Qu, Biaoyang Lin, Xisong Ke, Anne Margrete Øyan, Karl-Henning Kalland
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0177861 (2017)
The androgen receptor (AR) transcription factor plays a key role in the development and progression of prostate cancer, as is evident from the efficacy of androgen-deprivation therapy, AR is also the most frequently mutated gene, in castration resist
Externí odkaz:
https://doaj.org/article/3a63f1dfd7674a55960d2cc38fba377f
Autor:
Ingrid Moen, Anne Margrete Øyan, Karl-Henning Kalland, Karl Johan Tronstad, Lars Andreas Akslen, Martha Chekenya, Per Øystein Sakariassen, Rolf Kåre Reed, Linda Elin Birkhaug Stuhr
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6381 (2009)
Tumor hypoxia is relevant for tumor growth, metabolism and epithelial-to-mesenchymal transition (EMT). We report that hyperbaric oxygen (HBO) treatment induced mesenchymal-to-epithelial transition (MET) in a dimethyl-alpha-benzantracene induced mamma
Externí odkaz:
https://doaj.org/article/a3884f515921482aa1211cf6f8d11c41
Autor:
Xi-Song Ke, Yi Qu, Naomi Goldfinger, Kari Rostad, Randi Hovland, Lars A Akslen, Varda Rotter, Anne Margrete Øyan, Karl-Henning Kalland
Publikováno v:
PLoS ONE, Vol 3, Iss 10, p e3368 (2008)
BACKGROUND: Epithelial to mesenchymal transition (EMT) has been connected with cancer progression in vivo and the generation of more aggressive cancer cell lines in vitro. EMT has been induced in prostate cancer cell lines, but has previously not bee
Externí odkaz:
https://doaj.org/article/1b400e4a80504f42b5dd29276dda7690
Autor:
Øystein Bruserud, Anita Ryningen, Astrid Marta Olsnes, Laila Stordrange, Anne Margrete Øyan, Karl Henning Kalland, Bjørn Tore Gjertsen
Publikováno v:
Haematologica, Vol 92, Iss 3 (2007)
Background and Objectives Chemokines are soluble mediators involved in angiogenesis, cellular growth control and immunomodulation. In the present study we investigated the effects of various chemokines on proliferation of acute myelogenous leukemia (
Externí odkaz:
https://doaj.org/article/953f0da0fac24d928a75a3bc8e975a44
Autor:
Lars Andreas Akslen, Karl-Henning Kalland, Inge Jonassen, Leroy Hood, Svein Andreas Haukaas, Sue Olsen, Laila Stordrange, Trond Hellem Bø, Hanne Puntervoll, Anne Margrete Øyan, Kari Rostad, Ole Johan Halvorsen
Purpose: The human SIM2 gene is located within the Down's syndrome critical region of chromosome 21 and encodes transcription factors involved in brain development and neuronal differentiation. SIM2 has been assigned a possible role in the pathogenes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8361f4686d4008dad244643f0e4f9e4a
https://doi.org/10.1158/1078-0432.c.6518694
https://doi.org/10.1158/1078-0432.c.6518694
Autor:
Lars Andreas Akslen, Karl-Henning Kalland, Inge Jonassen, Leroy Hood, Svein Andreas Haukaas, Sue Olsen, Laila Stordrange, Trond Hellem Bø, Hanne Puntervoll, Anne Margrete Øyan, Kari Rostad, Ole Johan Halvorsen
Supplementary Figure 2 from Increased Expression of SIM2-s Protein Is a Novel Marker of Aggressive Prostate Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06a3ed549b49a258d5366f141c9b7b87
https://doi.org/10.1158/1078-0432.22441761
https://doi.org/10.1158/1078-0432.22441761