Výsledky vyhledávání - "Anne M. van Abbema"

Supplementary Data from Combinatorial efficacy of anti-CS1 monoclonal antibody elotuzumab (HuLuc63) and bortezomib against multiple myeloma

Autor: Daniel E.H. Afar, Shmuel Yaccoby, Bart Barlogie, John D. Shaughnessy, Fenghuang Zhan, Audie G. Rice, Debra Chao, Bishwa Ganguly, Balaji Balasa, Rui Yun, Amberly M. Moreno-Bost, JuMei Shi, Tarun K. Garg, Mary K. Stone, Xin Li, Anne M. van Abbema, Myles Dillon, Susann M. Szmania, Frits van Rhee

Supplementary Data from Combinatorial efficacy of anti-CS1 monoclonal antibody elotuzumab (HuLuc63) and bortezomib against multiple myeloma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22ceb3c738108976650d682599b1dbd3
https://doi.org/10.1158/1535-7163.22486031

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Data from Combinatorial efficacy of anti-CS1 monoclonal antibody elotuzumab (HuLuc63) and bortezomib against multiple myeloma

Monoclonal antibody (mAb) therapy for multiple myeloma, a malignancy of plasma cells, has not been clinically efficacious in part due to a lack of appropriate targets. We recently reported that the cell surface glycoprotein CS1 (CD2 subset 1, CRACC,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ef3d3e9283c21d752107367ae7e8ce8
https://doi.org/10.1158/1535-7163.c.6532202

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Rapid parallel synthesis applied to the optimization of a series of potent nonpeptide neuropeptide Y-1 receptor antagonists

Autor: Dennis M. Zimmerman, Miles Goodman Siegel, Gary A. Koppel, David C. Hunden, Patric James Hahn, Michael P. Clay, Robert F. Bruns, Anne M. Van Abbema, Donald R. Gehlert, Paul L. Ornstein, Douglas W. Johnson, Hamideh Zarrinmayeh, Douglas A. Schober, Michael O. Chaney, Buddy E. Cantrell

Publikováno v: Tetrahedron. 55:11619-11639

This study describes the integrated application of parallel synthesis and computational chemistry to the design of potent nonpeptide antagonists for the neuropeptide Y-1 (NPY1) receptor. A lead molecule was modeled in the active site of the NPY1 rece

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::316f9687be5a7143efde2baaa0d17744
https://doi.org/10.1016/s0040-4020(99)00683-3

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The Neuropeptide Y Y1 Antagonist, 1229U91, A Potent Agonist for the Human Pancreatic Polypeptide-Preferring (NPY Y4) Receptor

Autor: Robert F. Bruns, Anne M. Van Abbema, David L. Smiley, Douglas A. Schober, Donald R. Gehlert

Publikováno v: Peptides. 19:537-542

Schober, D. A., A. M. Van Abbema, D. L. Smiley, R. F. Bruns and D. R. Gehlert. The neuropeptide Y Y1 antagonist, 1229U91, a potent agonist for the human pancreatic polypeptide-preferring (NPY Y4) receptor. Peptides 19(3) 537–542, 1998.—Recently,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb00db7a5c2013c40017ece270404a2e
https://doi.org/10.1016/s0196-9781(97)00455-5

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