Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Anne M. Zimmer"'
Autor:
Bruno Pradier, Anne M. Zimmer, Ildiko Racz, Andreas Zimmer, A.-L. Klauke, Jürg Gertsch, Astrid Markert
Publikováno v:
European Neuropsychopharmacology. 24:608-620
The widespread plant volatile beta-caryophyllene (BCP) was recently identified as a natural selective agonist of the peripherally expressed cannabinoid receptor 2 (CB2). It is found in relatively high concentrations in many spices and food plants. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f5c40cfe2fc725bea77f63444baf377
https://doi.org/10.1016/j.euroneuro.2013.10.008
https://doi.org/10.1016/j.euroneuro.2013.10.008
Publikováno v:
Learning & Memory. 17:18-22
Cannabinoid CB1 receptor is abundantly expressed throughout the CNS and is implicated in numerous physiological and behavioral functions, including appetite and feeding. In the present study, wild-type and CB1 heterozygous and homozygous knockout mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb176c7b00adabc815548f4d3e031af9
https://doi.org/10.1101/lm.1610510
https://doi.org/10.1101/lm.1610510
Autor:
Ian Kitchen, Anne M. Zimmer, Daniel Weber, Andreas Zimmer, Susanna M.O. Hourani, Alexis Bailey
Publikováno v:
Brain Research. 1025:1-9
There is a large body of evidence indicating important interactions between the adenosine and the opioid systems in regulating pain, opioid dependence and withdrawal. Mice lacking the proenkephalin gene and therefore lacking the endogenous enkephalin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c0b891b3425ba2bacf76ee0082edb13
https://doi.org/10.1016/j.brainres.2004.06.088
https://doi.org/10.1016/j.brainres.2004.06.088
Autor:
Christopher S. Breivogel, W. Kirk Rorrer, Anne M. Zimmer, Dana E. Selley, Laura J. Sim-Selley, Andreas Zimmer, Billy R. Martin
Publikováno v:
Journal of Neurochemistry. 77:1048-1057
Heterozygous CB1 receptor knockout mice were used to examine the effect of reduced CB1 receptor density on G-protein activation in membranes prepared from four brain regions: cerebellum, hippocampus, striatum/globus pallidus (striatum/GP) and cingula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4bc3da95cfdf515d086db04753959278
https://doi.org/10.1046/j.1471-4159.2001.00308.x
https://doi.org/10.1046/j.1471-4159.2001.00308.x
Autor:
Roland Kappler, Ulrike Müller, Heidi Hahn, Andreas Zimmer, Elenore Samson, Diana Potter, Anne M. Zimmer, Julia Calzada-Wack, Leticia Quintanilla-Martinez, Leszek Wojnowski, Katja Specht
Publikováno v:
Journal of Biological Chemistry. 275:28341-28344
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children (Dagher, R., and Helman, L. (1999) Oncologist 4, 34-44), whereas medulloblastoma, a highly malignant tumor of the cerebellum, accounts for 20% of childhood brain tumors (Goodri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::763f8120ff9c1e320aadb2f61d4b1ca7
https://doi.org/10.1074/jbc.c000352200
https://doi.org/10.1074/jbc.c000352200
Autor:
Anne M. Zimmer, Andreas Zimmer, Raj K. Razdan, Jens A. Wagner, Billy R. Martin, Nancy E. Buckley, George Kunos, Tom I. Bonner, Zoltán Járai, Károly Varga, Kristy D. Lake, D R Compton, Eva Mezey
Publikováno v:
Proceedings of the National Academy of Sciences. 96:14136-14141
Cannabinoids, including the endogenous ligand arachidonyl ethanolamide (anandamide), elicit not only neurobehavioral but also cardiovascular effects. Two cannabinoid receptors, CB1 and CB2, have been cloned, and studies with the selective CB1 recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7194453a4598c35a33ba9b07e60433e
https://doi.org/10.1073/pnas.96.24.14136
https://doi.org/10.1073/pnas.96.24.14136
Publikováno v:
Proceedings of the National Academy of Sciences. 96:5780-5785
Δ 9 -Tetrahydrocannabinol (Δ 9 -THC), the major psychoactive ingredient in preparations of Cannabis sativa (marijuana, hashish), elicits central nervous system (CNS) responses, including cognitive alterations and euphoria. These responses account f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::561728072d1d2adff19bd4ba0a49e64f
https://doi.org/10.1073/pnas.96.10.5780
https://doi.org/10.1073/pnas.96.10.5780
Autor:
Ulf R. Rapp, Anne M. Zimmer, Andreas Zimmer, Louis F. Stancato, Andrew C. Larner, Leszek Wojnowski, Heidi Hahn, Thomas William Beck
Publikováno v:
Mechanisms of Development. 76:141-149
The three mammalian Raf serine/threonine protein kinases mediate the transduction of proliferative and differentiative signals from a variety of cell surface receptors to the nucleus. We report here that Craf-1 is essential for mouse development, as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaaccd3dba42feb995eaecfedba02412
https://doi.org/10.1016/s0925-4773(98)00111-7
https://doi.org/10.1016/s0925-4773(98)00111-7
Autor:
Heidi Hahn, Andreas Zimmer, Jennifer L. Hall, Georgina F. Miller, Leszek Wojnowski, Anne M. Zimmer
Publikováno v:
Nature Medicine. 4:619-622
Gorlin (or nevoid basal cell carcinoma) syndrome is characterized by a variety of clinical problems including generalized overgrowth of the body, cysts, developmental abnormalities of the skeleton and a predisposition to benign and malignant tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::583bf04b3ef4d0a1e7550dadbe2e5207
https://doi.org/10.1038/nm0598-619
https://doi.org/10.1038/nm0598-619
Autor:
Ricardo A. Bernal, Anne M. Zimmer, Ulf R. Rapp, Leszek Wojnowski, Heidi Hahn, Andreas Zimmer, Thomas William Beck
Publikováno v:
Nature Genetics. 16:293-297
Tyrosine kinase growth factor receptors and Ras/Raf/MEK/MAPK signalling have been implicated in the suppression1–3 as well as augmentation of programmed cell death4. In addition, a Ras-independent role for Raf as a suppressor of programmed cell dea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6059636ab78b75cf12b41057f95b3d6
https://doi.org/10.1038/ng0797-293
https://doi.org/10.1038/ng0797-293