Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Anne M. Latour"'
Autor:
Ok Ju Sul, Anne M. Latour, Jae Hee Seo, Hee Young Park, Woon-Ki Kim, Byoung S. Kwon, Choon Soo Jeong, Byum Kyu Choi, Beverly H. Koller, Jin-Soo Park
Publikováno v:
Molecules and Cells. 31:99-104
Previous work has suggested that the LIGHT-TR2 costimulatory pathway plays a role in the acute and chronic stages of dextran sulfate sodium (DSS)-induced colitis [Steinberg et al. (2008); Wang et al. (2005)]. To clarify the role of TNFR-related 2 (TR
Autor:
Leigh A. Jania, Julie G. Ledford, John N. Snouwaert, Anne M. Latour, Virginie Bernier, Beverly H. Koller, Alex G. Therien, Amy J. Pace, Irving C. Allen, Rino Stocco
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 291:L1005-L1017
A genetic contribution to asthma susceptibility is well recognized, and linkage studies have identified a large number of genes associated with asthma pathogenesis. Recently, a locus encoding a seven-transmembrane protein was shown to be associated w
Autor:
Cristin M. Galardi, Austin J. Cooney, Bryan Goodwin, Steven A. Kliewer, Peili Gu, Beverly H. Koller, Jan A. Gossen, Roger R. Price, David A. Wheeler, Anne M. Latour, Li Peng, Arthur C.-K. Chung, Xueping Xu
Publikováno v:
Molecular and Cellular Biology. 25:3492-3505
Oct4 plays an essential role in maintaining the inner cell mass and pluripotence of embryonic stem (ES) cells. The expression of Oct4 is regulated by the proximal enhancer and promoter in the epiblast and by the distal enhancer and promoter at all ot
Autor:
MyTrang Nguyen, Peter W. Repenning, John N. Snouwaert, Zhidan Xiang, Anne M. Latour, Jaime M. Cyphert, Beverly H. Koller, Martina Kovarova
Glutathione S-transferases (GSTs) form a superfamily defined by their ability to catalyze the conjugation of glutathione with electrophilic substrates. These enzymes are proposed to play a critical role in protection of cellular components from damag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae6b94e32eb89f0fd193ad14ef1f7337
https://europepmc.org/articles/PMC4014662/
https://europepmc.org/articles/PMC4014662/
Autor:
Bryan Goodwin, Kathleen K. Brown, Yaping Liu, John F. Reinhard, Diane Hawkins-Brown, Stacey A. Jones, Curtis D. Klaassen, Jeff L. Staudinger, Kathleen I. MacKenzie, Anne M. Latour, Timothy M. Willson, Beverly H. Koller, Steven A. Kliewer
Publikováno v:
Proceedings of the National Academy of Sciences. 98:3369-3374
The pregnane X receptor (PXR) is the molecular target for catatoxic steroids such as pregnenolone 16α-carbonitrile (PCN), which induce cytochrome P450 3A ( CYP3A ) expression and protect the body from harmful chemicals. In this study, we demonstrate
Autor:
Andrew Xiao, Amy R. Mohn, John N. Snouwaert, Anne M. Latour, Beverly H. Koller, Lauren M. DiBiase, Lori C. Gowen
Publikováno v:
Oncogene. 18:7900-7907
BRCA1 is a nuclear phosphoprotein that has been classified as a tumor suppressor based on the fact that women carrying a mutated copy of the BRCA1 gene are at increased risk of developing breast and ovarian cancer. The association of BRCA1 with RAD51
Autor:
Jayne A. Keifer, Jean-Etienne Fabre, Anne M. Latour, Laurent P. Audoly, Thomas M. Coffman, MyTrang Nguyen, Beverly H. Koller
Publikováno v:
Nature Medicine. 5:1199-1202
Platelet activation is characterized by shape change, induction of fibrinogen receptor expression and release of granular contents, leading to aggregation and plug formation. While this response is essential for hemostasis, it is also important in th
Publikováno v:
Science. 281:1009-1012
The breast and ovarian cancer susceptibility geneBRCA1encodes a zinc finger protein of unknown function. Association of the BRCA1 protein with the DNA repair protein Rad51 and changes in the phosphorylation and cellular localization of the protein af
Brca1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities
Publikováno v:
Nature Genetics. 12:191-194
The breast and ovarian cancer susceptibility gene, BRCA1, has been cloned and shown to encode a zinc-finger protein of unknown function. Mutations in BRCA1 account for at least 80% of families with both breast and ovarian cancer, as well as some non-
Autor:
Ute E. Schwab, M.I. Gilmour, John N. Snouwaert, Beverly H. Koller, Elizabeth Iraj, Kristen K. Brigman, Anne M. Latour
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 151:S59-S64
We have generated a mouse line in which the cystic fibrosis transmembrane conductance regulator (CFTR) gene has been mutated by gene targeting. Like human cystic fibrosis (CF) patients, mice lacking a functional CFTR gene, referred to as CFTR(-/-) mi