Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Anne M. Kong"'
Autor:
Jarmon G. Lees, David W. Greening, David A. Rudd, Jonathon Cross, Ayeshah A. Rosdah, Xiangfeng Lai, Tsung Wu Lin, Ren Jie Phang, Anne M. Kong, Yali Deng, Simon Crawford, Jessica K. Holien, Derek J. Hausenloy, Hsin-Hui Shen, Shiang Y. Lim
Publikováno v:
Journal of Molecular and Cellular Cardiology Plus, Vol 9, Iss , Pp 100085- (2024)
Dynamin-related protein 1 (Drp1) is a mitochondrial fission protein and a viable target for cardioprotection against myocardial ischaemia-reperfusion injury. Here, we reported a novel Drp1 inhibitor (DRP1i1), delivered using a cardiac-targeted nanopa
Externí odkaz:
https://doaj.org/article/c5ae7e34af804835a24c75f371f23c34
NOS3 regulates angiogenic potential of human induced pluripotent stem cell-derived endothelial cells
Autor:
Anne M. Kong, Zulhusni A. Idris, Daniel Urrutia-Cabrera, Jarmon G. Lees, Ren Jie Phang, Geraldine M. Mitchell, Raymond C.B. Wong, Shiang Y. Lim
Publikováno v:
Biochemistry and Biophysics Reports, Vol 40, Iss , Pp 101876- (2024)
Incorporation of blood capillaries in engineered tissues and their functional connection to host blood vessels is essential for success in engineering vascularized tissues, a process which involves spatial patterning of endothelial cells (ECs) to for
Externí odkaz:
https://doaj.org/article/3bda5a01d9c2428a96a8000999628684
Autor:
Kiryu K. Yap, Jan Schröder, Yi-Wen Gerrand, Aleksandar Dobric, Anne M. Kong, Adrian M. Fox, Brett Knowles, Simon W. Banting, Andrew G. Elefanty, Eduoard G. Stanley, George C. Yeoh, Glen P. Lockwood, Victoria C. Cogger, Wayne A. Morrison, Jose M. Polo, Geraldine M. Mitchell
Publikováno v:
JHEP Reports, Vol 6, Iss 5, Pp 101023- (2024)
Background & Aims: Liver sinusoidal endothelial cells (LSECs) are important in liver development, regeneration, and pathophysiology, but the differentiation process underlying their tissue-specific phenotype is poorly understood and difficult to stud
Externí odkaz:
https://doaj.org/article/e8a0dc074d684146bd805a7e443ce74f
Autor:
Quanxia Lyu, Shu Gong, Jarmon G. Lees, Jialiang Yin, Lim Wei Yap, Anne M. Kong, Qianqian Shi, Runfang Fu, Qiang Zhu, Ash Dyer, Jennifer M. Dyson, Shiang Y. Lim, Wenlong Cheng
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
It is challenging to directly characterize mechanical properties of soft 3D cardiac organoids with current sensors. Here the authors report an electronic skin-based all-soft organoid-sensing system which can wirelessly monitor minute force profiles o
Externí odkaz:
https://doaj.org/article/afa1825aa9394eed867874bf4d43c70c
Autor:
Jarmon G. Lees, Anne M. Kong, Yi C. Chen, Priyadharshini Sivakumaran, Damián Hernández, Alice Pébay, Alexandra J. Harvey, David K. Gardner, Shiang Y. Lim
Publikováno v:
Stem Cells International, Vol 2019 (2019)
Human induced pluripotent stem cells (iPSCs) can be differentiated in vitro into bona fide cardiomyocytes for disease modelling and personalized medicine. Mitochondrial morphology and metabolism change dramatically as iPSCs differentiate into mesoder
Externí odkaz:
https://doaj.org/article/85ccbf95dccf420887dafb2aa41ba1df
Autor:
Anne M Kong, Shiang Y Lim, Jason A Palmer, Amanda Rixon, Yi-Wen Gerrand, Kiryu K Yap, Wayne A Morrison, Geraldine M Mitchell
Publikováno v:
Journal of tissue engineering. 13
Due to a relative paucity of studies on human lymphatic assembly in vitro and subsequent in vivo transplantation, capillary formation and survival of primary human lymphatic (hLEC) and blood endothelial cells (hBEC) ± primary human vascular smooth m
Autor:
Anne M. Kong, Gregory J. Dusting, Shiang Y. Lim, Priyadharshini Sivakumaran, Owen Burns, Damián Hernández, Robert K. Shepherd, Rodney E. Millard
Publikováno v:
Bioelectricity
Background: Cardiomyocytes derived from pluripotent stem cells are immature. Maturation of cardiomyocytes is a multifactorial dynamic process that involves various factors in vivo that cannot be fully recapitulated in vitro. Here, we report a novel t
Autor:
Elsa C Chan, Shyh-Ming Kuo, Anne M Kong, Wayne A Morrison, Gregory J Dusting, Geraldine M Mitchell, Shiang Y Lim, Guei-Sheung Liu
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149799 (2016)
Here, we describe a porous 3-dimensional collagen scaffold material that supports capillary formation in vitro, and promotes vascularization when implanted in vivo. Collagen scaffolds were synthesized from type I bovine collagen and have a uniform po
Externí odkaz:
https://doaj.org/article/a1722d3c9f8b4dffb0d1f740eed7a5c0
Autor:
Yi Ching Chen, Jarmon G Lees, David K. Gardner, Shiang Y. Lim, Alice Pébay, Anne M. Kong, Alexandra J Harvey, Damián Hernández, Priyadharshini Sivakumaran
Publikováno v:
Stem Cells International
Stem Cells International, Vol 2019 (2019)
Stem Cells International, Vol 2019 (2019)
Human induced pluripotent stem cells (iPSCs) can be differentiated in vitro into bona fide cardiomyocytes for disease modelling and personalized medicine. Mitochondrial morphology and metabolism change dramatically as iPSCs differentiate into mesoder
Autor:
Geraldine M. Mitchell, Kiryu K. Yap, Jarmon G Lees, Diego Marre, Shiang Y. Lim, Wayne A. Morrison, Jason A. Palmer, Yi-Wen Gerrand, Anne M. Kong, Alice Pébay
Publikováno v:
Acta Biomaterialia. 94:281-294
Tissue flaps are used to cover large/poorly healing wounds, but involve complex surgery and donor site morbidity. In this study a tissue flap is assembled using the mammalian body as a bioreactor to functionally connect an artery and vein to a human