Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Anne M. Grifiths"'
Autor:
Tzipi Braun, Katya E. Sosnovski, Amnon Amir, Marina BenShoshan, Kelli L. VanDussen, Rebekah Karns, Nina Levhar, Haya Abbas-Egbariya, Rotem Hadar, Gilat Efroni, David Castel, Camila Avivi, Michael J. Rosen, Anne M. Grifiths, Thomas D. Walters, David R. Mack, Brendan M. Boyle, Syed Asad Ali, Sean R. Moore, Melanie Schirmer, Ramnik J. Xavier, Subra Kugathasan, Anil G. Jegga, Batya Weiss, Chen Mayer, Iris Barshack, Shomron Ben-Horin, Igor Ulitsky, Anthony Beucher, Jorge Ferrer, Jeffrey S. Hyams, Lee A. Denson, Yael Haberman
Publikováno v:
JCI Insight, Vol 8, Iss 14 (2023)
Ulcerative colitis (UC), Crohn’s disease (CD), and celiac disease are prevalent intestinal inflammatory disorders with nonsatisfactory therapeutic interventions. Analyzing patient data-driven cohorts can highlight disease pathways and new targets f
Externí odkaz:
https://doaj.org/article/175d48f8e9c64094a115fe7ffb8e26b5
Autor:
Yael Haberman, Rebekah Karns, Phillip J. Dexheimer, Melanie Schirmer, Judith Somekh, Ingrid Jurickova, Tzipi Braun, Elizabeth Novak, Laura Bauman, Margaret H. Collins, Angela Mo, Michael J. Rosen, Erin Bonkowski, Nathan Gotman, Alison Marquis, Mason Nistel, Paul A. Rufo, Susan S. Baker, Cary G. Sauer, James Markowitz, Marian D. Pfefferkorn, Joel R. Rosh, Brendan M. Boyle, David R. Mack, Robert N. Baldassano, Sapana Shah, Neal S. Leleiko, Melvin B. Heyman, Anne M. Grifiths, Ashish S. Patel, Joshua D. Noe, Bruce J. Aronow, Subra Kugathasan, Thomas D. Walters, Greg Gibson, Sonia Davis Thomas, Kevin Mollen, Shai Shen-Orr, Curtis Huttenhower, Ramnik J. Xavier, Jeffrey S. Hyams, Lee A. Denson
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
The severity of ulcerative colitis, and response to treatment, is highly variable. Here, the authors examine rectal gene expression signatures and faecal microbiomes of children and adults with the disease and provide new insights in to pathogenesis.
Externí odkaz:
https://doaj.org/article/cbe3d637f8854aa08026fcc4f3d0a9e7
Autor:
Susan S. Baker, Melanie Schirmer, Alison Marquis, Joel R. Rosh, Cary G. Sauer, Laura Bauman, Mason Nistel, Phillip J. Dexheimer, James Markowitz, Kevin P. Mollen, Sapana Shah, Neal S. Leleiko, Anne M. Grifiths, Paul A. Rufo, Robert N. Baldassano, Rebekah Karns, Elizabeth Novak, Ashish S. Patel, Melvin B. Heyman, Judith Somekh, Yael Haberman, Erin Bonkowski, Ingrid Jurickova, Thomas D. Walters, Brendan M. Boyle, Tzipi Braun, Nathan Gotman, Angela Mo, Jeffrey S. Hyams, Curtis Huttenhower, Sonia Davis Thomas, Subra Kugathasan, Ramnik J. Xavier, Lee A. Denson, Marian D. Pfefferkorn, Greg Gibson, Joshua D. Noe, Bruce J. Aronow, Michael J. Rosen, Shai S. Shen-Orr, Margaret H. Collins, David R. Mack
Publikováno v:
Nature communications, vol 10, iss 1
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Molecular mechanisms driving disease course and response to therapy in ulcerative colitis (UC) are not well understood. Here, we use RNAseq to define pre-treatment rectal gene expression, and fecal microbiota profiles, in 206 pediatric UC patients re