Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Anne M. Evans"'
Autor:
Nilanjana Ghosh, Carl Lejonberg, Tomasz Czuba, Koen Dekkers, Richard Robinson, Johan Ärnlöv, Olle Melander, Maya Landenhed Smith, Anne M. Evans, Olof Gidlöf, Robert E. Gerszten, Lars Lind, Gunnar Engström, Tove Fall, J. Gustav Smith
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Plasma metabolomics holds potential for precision medicine, but limited information is available to compare the performance of such methods across multiple cohorts. We compared plasma metabolite profiles after an overnight fast in 11,309 par
Externí odkaz:
https://doaj.org/article/07c3b0b4011d4fd3972f0e6ac665caac
Autor:
Karen L. DeBalsi, John H. Newman, Laura J. Sommerville, John A. Phillips, Rizwan Hamid, Joy Cogan, Joshua P. Fessel, Anne M. Evans, Undiagnosed Diseases Network, Adam D. Kennedy
Publikováno v:
Metabolites, Vol 13, Iss 3, p 399 (2023)
We present a case study of a 20-year-old male with an unknown neurodegenerative disease who was referred to the Undiagnosed Diseases Network Vanderbilt Medical Center site. A previous metabolic panel showed that the patient had a critical deficiency
Externí odkaz:
https://doaj.org/article/121161c89d9a46c4b9ec32cc3cba8184
Autor:
Sivapriya Ramamoorthy, Shira Levy, Masouma Mohamed, Alaa Abdelghani, Anne M. Evans, Luke A. D. Miller, Lopa Mehta, Sean Moore, Elizaveta Freinkman, Suchitra K. Hourigan
Publikováno v:
BMC Microbiology, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Stool metabolites provide essential insights into the function of the gut microbiome. The current gold standard for storage of stool samples for metabolomics is flash-freezing at − 80 °C which can be inconvenient and expensive.
Externí odkaz:
https://doaj.org/article/10db1355326c4899bcb0816039dc4230
Autor:
Ruifang Li-Gao, Kirk Grubbs, Alain G. Bertoni, Kristi L. Hoffman, Joseph F. Petrosino, Gautam Ramesh, Martin Wu, Jerome I. Rotter, Yii-Der Ida Chen, Anne M. Evans, Richard J. Robinson, Laura Sommerville, Dennis Mook-Kanamori, Mark O. Goodarzi, Gregory A. Michelotti, Patricia A. Sheridan
Publikováno v:
Metabolites, Vol 12, Iss 9, p 787 (2022)
Non-O blood groups are associated with decreased insulin sensitivity and risk of type 2 diabetes. A recent study pinpointed the associations between ABO blood groups and gut microbiome, which may serve as potential mediators for the observed increase
Externí odkaz:
https://doaj.org/article/ddca9e3a9b9d42d2b7dc7d8fc4a1edaa
Autor:
Adam D Kennedy, Lisa Ford, Bryan Wittmann, Jesse Conner, Jacob Wulff, Matthew Mitchell, Anne M Evans, Douglas R Toal
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0249797 (2021)
IntroductionAnalysis of blood for the evaluation of clinically relevant biomarkers requires precise collection and sample handling by phlebotomists and laboratory staff. An important consideration for the clinical application of metabolomics are the
Externí odkaz:
https://doaj.org/article/e2d1db67b3934997bbe2525e1c2b71fa
Autor:
Gaurav Thareja, Anne M. Evans, Spencer D. Wood, Nisha Stephan, Shaza Zaghlool, Anna Halama, Gabi Kastenmüller, Aziz Belkadi, Omar M. E. Albagha, The Qatar Genome Program Research Consortium, Karsten Suhre
Publikováno v:
Metabolites, Vol 12, Iss 6, p 496 (2022)
Genome-wide association studies (GWAS) with non-targeted metabolomics have identified many genetic loci of biomedical interest. However, metabolites with a high degree of missingness, such as drug metabolites and xenobiotics, are often excluded from
Externí odkaz:
https://doaj.org/article/8ae1076577854fff893f9f63a2fbdfe7
Autor:
Karsten Suhre, Nisha Stephan, Shaza Zaghlool, Chris R. Triggle, Richard J. Robinson, Anne M. Evans, Anna Halama
Publikováno v:
Metabolites, Vol 12, Iss 3, p 249 (2022)
Modern metabolomics platforms are able to identify many drug-related metabolites in blood samples. Applied to population-based biobank studies, the detection of drug metabolites can then be used as a proxy for medication use or serve as a validation
Externí odkaz:
https://doaj.org/article/7bd89b5539774584aa815a32d6c9d07d
Autor:
Adam D. Kennedy, Kirk L. Pappan, Taraka Donti, Mauricio R. Delgado, Marwan Shinawi, Toni S. Pearson, Seema R. Lalani, William J. Craigen, V. Reid Sutton, Anne M. Evans, Qin Sun, Lisa T. Emrick, Sarah H. Elsea
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2020)
Externí odkaz:
https://doaj.org/article/17451995e3364e8288022166b2a33f82
Autor:
Adam D. Kennedy, Kirk L. Pappan, Taraka Donti, Mauricio R. Delgado, Marwan Shinawi, Toni S. Pearson, Seema R. Lalani, William J. Craigen, V. Reid Sutton, Anne M. Evans, Qin Sun, Lisa T. Emrick, Sarah H. Elsea
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Broad-scale untargeted biochemical phenotyping is a technology that supplements widely accepted assays, such as organic acid, amino acid, and acylcarnitine analyses typically utilized for the diagnosis of inborn errors of metabolism. In this study, w
Externí odkaz:
https://doaj.org/article/fa885f19fefe4f869890129fee0605d5
Autor:
Kelli Goodman, Megan R. Showalter, Anne M. Evans, Matthew W. Mitchell, Rangaprasad Sarangarajan
Publikováno v:
Cancer Research. 83:6607-6607
The COVID19 pandemic accelerated opportunities for innovation within the decentralization process of clinical trials with opportunities for implementation of patient-centric workflows for efficiency and cost-reduction. Decentralized sample collection