Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Anne M. Cunningham"'
Autor:
Chris Davies, Simon Thompson, Sinead Brophy, Tamas Szakmany, Amy Mizen, Richard Fry, Jan Davies, Gareth John, Chris Orton, James Rafferty, Christopher Williams, Gareth I Davies, Rowena Bailey, Joseph Hollinghurst, Samantha L Turner, Lee Au-Yeung, Lynsey Cross, Mike B Gravenor, Biagio Lucini, Daniel Rh Thomas, Chris Emmerson, Simon Cottrell, Thomas R Connor, Chris Taylor, Richard J Pugh, Simon Scourfield, Joe Hunt, Anne M Cunningham, Kathryn Helliwell
Publikováno v:
BMJ Open, Vol 10, Iss 10 (2020)
Introduction The emergence of the novel respiratory SARS-CoV-2 and subsequent COVID-19 pandemic have required rapid assimilation of population-level data to understand and control the spread of infection in the general and vulnerable populations. Rap
Externí odkaz:
https://doaj.org/article/75895aaf285949d881a072d8d245b518
Autor:
Maria Kavallaris, David E. Hibbs, Anne M. Cunningham, Matthew J. McKay, Noeris K. Salam, Tracy Y.E. Liaw
Supplementary Table S1 from Class I β-tubulin mutations in 2-methoxyestradiol-resistant acute lymphoblastic leukemia cells: implications for drug-target interactions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dc5255bfdd043cfb47d789371ea28fe
https://doi.org/10.1158/1535-7163.22482140
https://doi.org/10.1158/1535-7163.22482140
Autor:
Maria Kavallaris, David E. Hibbs, Anne M. Cunningham, Matthew J. McKay, Noeris K. Salam, Tracy Y.E. Liaw
Supplementary Fig. S1 legend from Class I β-tubulin mutations in 2-methoxyestradiol-resistant acute lymphoblastic leukemia cells: implications for drug-target interactions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::772be5d99c224f0df854eba7c1844d63
https://doi.org/10.1158/1535-7163.22482143
https://doi.org/10.1158/1535-7163.22482143
Autor:
Maria Kavallaris, David E. Hibbs, Anne M. Cunningham, Matthew J. McKay, Noeris K. Salam, Tracy Y.E. Liaw
2-Methoxyestradiol (2ME2) is a naturally occurring derivative of estradiol that has been shown to be an active small molecule that has antitumor and antiangiogenic properties. 2ME2 binds to β-tubulin near the colchicine-binding site, inhibits microt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06ca811deb9874fcfee4fc9dd5a5e10e
https://doi.org/10.1158/1535-7163.c.6530834
https://doi.org/10.1158/1535-7163.c.6530834
Autor:
Maria Kavallaris, David E. Hibbs, Anne M. Cunningham, Matthew J. McKay, Noeris K. Salam, Tracy Y.E. Liaw
Supplementary Fig. S1 from Class I β-tubulin mutations in 2-methoxyestradiol-resistant acute lymphoblastic leukemia cells: implications for drug-target interactions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::655078965b6c29d77fac48f5332047d6
https://doi.org/10.1158/1535-7163.22482146.v1
https://doi.org/10.1158/1535-7163.22482146.v1
Publikováno v:
Reproductive Toxicology. 78:81-89
Buprenorphine, a mu opioid receptor partial agonist and kappa opioid receptor (KOR) antagonist, is an emerging therapeutic agent for maternal opioid dependence in pregnancy and neonatal abstinence syndrome. However, the endogenous opioid system plays
Autor:
Katherine Bryant, Stephen J. Harrop, Lawrence K. Lee, Anthony P. Duff, Kieran F. Scott, Richard P. Harvey, Michael H. Gelb, Pei Wen Lei, Romaric Bouveret, W. Bret Church, Edwin P. Huang, Anne M. Cunningham, Peter P. Gray, Paul M. G. Curmi
Publikováno v:
Journal of Biological Chemistry. 288:15269-15279
Human group IIA secreted phospholipase A2 (hGIIA) promotes tumor growth and inflammation and can act independently of its well described catalytic lipase activity via an alternative poorly understood signaling pathway. With six chemically diverse inh
Autor:
James S. Wilmott, Selina K. Sutton, A Malyukova, Glenn M. Marshall, Patrick Y. Kim, Jessica L. Bell, Carla D’andreti, Jessica Koach, Charlotte M. Proby, Eric Sekyere, Anne M. Cunningham, Richard A. Scolyer, Michelle Haber, Murray D. Norris, Maria Kavallaris, Belamy B. Cheung, Irene M. Leigh, Owen Tan, Gary M. Halliday, Caroline L. Cooper
Publikováno v:
The Journal of Pathology
Retinoid therapy is used for chemo-prevention in immuno-suppressed patients at high risk of developing skin cancer. The retinoid signalling molecule, tripartite motif protein 16 (TRIM16), is a regulator of keratinocyte differentiation and a tumour su
Publikováno v:
Journal of Neurosurgery: Spine. 14:573-582
Object Endogenous stem cells theoretically could replace lost tissue and repair deficits caused by syringes. In this study the authors quantitatively examined 1) whether neural progenitor cells exist in an adult rat model of posttraumatic syringomyel
Autor:
Eric Sekyere, Anne M. Cunningham, Patrick Y. Kim, A Malyukova, Jessica Koach, Belamy B. Cheung, Jessica L. Bell, Wayne Thomas, Tao Liu, Maria Kavallaris, Murray D. Norris, Vivienne Tobias, Glenn M. Marshall, Michelle Haber, Owen Tan
Publikováno v:
Oncogene
The family of tripartite-motif (TRIM) proteins are involved in diverse cellular processes, but are often characterized by critical protein-protein interactions necessary for their function. TRIM16 is induced in different cancer types, when the cancer