Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Anne M. Crompton"'
Autor:
Lewis C. Cantley, Athar H. Chishti, C. Fu, Shirin M. Marfatia, Zhou Songyang, Alan S. Fanning, James M. Anderson, Jian Xu, Anne M. Crompton, Andrew C. Chan
Publikováno v:
Science. 275:73-77
The oriented peptide library technique was used to investigate the peptide-binding specificities of nine PDZ domains. Each PDZ domain selected peptides with hydrophobic residues at the carboxyl terminus. Individual PDZ domains selected unique optimal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a101000ca18faed76c523a80fa3aa32
https://doi.org/10.1126/science.275.5296.73
https://doi.org/10.1126/science.275.5296.73
Autor:
Daniel A. Coleman, Cynthia L. Adams, Vadim Kutsyy, Eugeni A. Vaisberg, Ge Cong, Kathleen A Elias, Anne M. Crompton, Donald R. Oestreicher, Jay Trautman
Compounds with similar target specificities and modes of inhibition cause similar cellular phenotypes. Based on this observation, we hypothesized that we could quantitatively classify compounds with diverse mechanisms of action using cellular phenoty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35ee9fc779838fac048e41eb3e61c949
https://doi.org/10.1016/s0076-6879(06)14024-0
https://doi.org/10.1016/s0076-6879(06)14024-0
Autor:
Christophe Beraud, Paul Gonzales, Jeffrey T. Finer, Evan R. Lewis, Kenneth W. Wood, Steven D. Weitman, Rebecca Turincio, Robert Moody, Anne M. Crompton, John C. Chabala, Roman Sakowicz, John Mak, Yan Lee, Stephanie Roth, Alex Fritsch
Publikováno v:
Cancer research. 64(9)
Several members of the kinesin family of microtubule motor proteins play essential roles in mitotic spindle function and are potential targets for the discovery of novel antimitotic cancer therapies. KSP, also known as HsEg5, is a kinesin that plays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c36b52b0bf53d4cdc49d7b5d7a4f6c9
https://pubmed.ncbi.nlm.nih.gov/15126370
https://pubmed.ncbi.nlm.nih.gov/15126370
Autor:
William Roscoe, Louise H. Foley, Gideon Bollag, Alexander W. Wood, David Stokoe, Marc Symons, Anne M. Crompton, Frank McCormick
Publikováno v:
The Journal of biological chemistry. 275(33)
Rho family GTPases play roles in cytoskeletal organization and cellular transformation. Tiam1 is a member of the Dbl family of guanine nucleotide exchange factors that activate Rho family GTPases. These exchange factors have in common a catalytic Dbl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acd28e28a2fabb7b91ff78917cb5b8ef
https://pubmed.ncbi.nlm.nih.gov/10835422
https://pubmed.ncbi.nlm.nih.gov/10835422
Publisher Summary This chapter describes the process of activation of Rac1 by human T-lymphoma invasion and metastasis 1 (Tiam1). The small GTPase Rac1 becomes activated via catalyzed displacement of bound GDP by a guanine nucleotide exchange factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0544da34a659020ad160bd6c842446fa
https://doi.org/10.1016/s0076-6879(00)25430-x
https://doi.org/10.1016/s0076-6879(00)25430-x
Autor:
Lucia E. Rameh, Michael P. Czech, Steven J. Burakoff, Anthony D. Couvillon, Kodimangalam S. Ravichandran, Lewis C. Cantley, Da Sheng Wang, Barbara VanRenterghem, Ann Kristin Arvidsson, Gary Rathbun, Ching Shih Chen, Anne M. Crompton, Kermit L. Carraway
Publikováno v:
The Journal of biological chemistry. 272(35)
Pleckstrin homology (PH) and phosphotyrosine binding (PTB) domains are structurally related regulatory modules that are present in a variety of proteins involved in signal transduction, such as kinases, phospholipases, GTP exchange proteins, and adap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3153d0831e8a1b30a7f7b2ae3d9a0465
https://pubmed.ncbi.nlm.nih.gov/9268346
https://pubmed.ncbi.nlm.nih.gov/9268346